Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50039514
TargetDNA polymerase kappa(Human)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379292(CHEMBL2011646)
Affinity DataIC50: 4.86E+4nMAssay Description:Competitive inhibition of human C-terminal-His6-tagged DNA polymerase kappa expressed in Escherichia coli using dTTP as substrate by Dixon plot analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDNA polymerase iota(Mouse)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379292(CHEMBL2011646)
Affinity DataIC50: 5.02E+4nMAssay Description:Inhibition of mouse recombinant C-terminal-His6-tagged DNA polymerase iota assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDNA polymerase nu(Human)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379292(CHEMBL2011646)
Affinity DataIC50: 5.09E+4nMAssay Description:Inhibition of C-terminal-His6-tagged human pol nu expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDNA polymerase delta catalytic subunit(Human)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379292(CHEMBL2011646)
Affinity DataIC50: 5.45E+4nMAssay Description:Inhibition of human DNA polymerase delta assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDNA polymerase kappa(Human)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379293(CHEMBL2011648)
Affinity DataIC50: 5.98E+4nMAssay Description:Competitive inhibition of human C-terminal-His6-tagged DNA polymerase kappa expressed in Escherichia coli using dTTP as substrate by Dixon plot analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDNA polymerase nu(Human)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379293(CHEMBL2011648)
Affinity DataIC50: 6.31E+4nMAssay Description:Inhibition of C-terminal-His6-tagged human pol nu expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDNA polymerase iota(Mouse)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379293(CHEMBL2011648)
Affinity DataIC50: 6.38E+4nMAssay Description:Inhibition of mouse recombinant C-terminal-His6-tagged DNA polymerase iota assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDNA polymerase delta catalytic subunit(Human)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379293(CHEMBL2011648)
Affinity DataIC50: 6.80E+4nMAssay Description:Inhibition of human DNA polymerase delta assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDNA polymerase kappa(Human)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379294(CHEMBL2011647)
Affinity DataIC50: 8.89E+4nMAssay Description:Competitive inhibition of human C-terminal-His6-tagged DNA polymerase kappa expressed in Escherichia coli using dTTP as substrate by Dixon plot analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDNA polymerase iota(Mouse)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379294(CHEMBL2011647)
Affinity DataIC50: 9.10E+4nMAssay Description:Inhibition of mouse recombinant C-terminal-His6-tagged DNA polymerase iota assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDNA polymerase nu(Human)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379294(CHEMBL2011647)
Affinity DataIC50: 9.21E+4nMAssay Description:Inhibition of C-terminal-His6-tagged human pol nu expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDNA polymerase delta catalytic subunit(Human)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379294(CHEMBL2011647)
Affinity DataIC50: 9.64E+4nMAssay Description:Inhibition of human DNA polymerase delta assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDNA polymerase lambda(Human)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379294(CHEMBL2011647)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human recombinant His-tagged DNA polymerase lambda expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDNA nucleotidylexotransferase(Bovine)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379292(CHEMBL2011646)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of calf TdT assessed as inhibition of incorporation of dTTP into oligo(dT)18(3'OH) after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDNA-directed DNA/RNA polymerase mu(Human)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379293(CHEMBL2011648)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human His-tagged recombinant DNA polymerase mu expressed in Escherichia coli BL21 assessed as inhibition of incorporation of dTTP into ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDNA polymerase lambda(Human)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379293(CHEMBL2011648)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human recombinant His-tagged DNA polymerase lambda expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Mouse)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379292(CHEMBL2011646)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of mouse IMP dehydrogenase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDNA-directed DNA polymerase(Enterobacteria phage T4)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379293(CHEMBL2011648)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of T4 bacteriophage DNA polymerase assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Mouse)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379294(CHEMBL2011647)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of mouse IMP dehydrogenase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Mouse)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379293(CHEMBL2011648)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of mouse IMP dehydrogenase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDNA nucleotidylexotransferase(Bovine)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379293(CHEMBL2011648)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of calf TdT assessed as inhibition of incorporation of dTTP into oligo(dT)18(3'OH) after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDNA polymerase beta(Rat)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379293(CHEMBL2011648)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of rat DNA polymerase beta expressed in Escherichia coli JMpbeta5 assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDeoxyribonuclease-1(Bovine)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379294(CHEMBL2011647)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of bovine deoxyribonuclease 1 using [3H]-labelled DNA after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPolynucleotide kinase(Enterobacteria phage T4)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379294(CHEMBL2011647)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of T4 arnN8l pseT 1 polynucleotide kinase assessed as inhibition of Salmon sperm DNA phosphorylation using [gamma32P]ATP by liquid scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDNA-directed DNA polymerase(Enterobacteria phage T4)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379294(CHEMBL2011647)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of T4 bacteriophage DNA polymerase assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDNA nucleotidylexotransferase(Bovine)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379294(CHEMBL2011647)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of calf TdT assessed as inhibition of incorporation of dTTP into oligo(dT)18(3'OH) after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDNA-directed DNA/RNA polymerase mu(Human)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379294(CHEMBL2011647)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human His-tagged recombinant DNA polymerase mu expressed in Escherichia coli BL21 assessed as inhibition of incorporation of dTTP into ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDNA polymerase beta(Rat)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379294(CHEMBL2011647)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of rat DNA polymerase beta expressed in Escherichia coli JMpbeta5 assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDeoxyribonuclease-1(Bovine)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379292(CHEMBL2011646)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of bovine deoxyribonuclease 1 using [3H]-labelled DNA after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPolynucleotide kinase(Enterobacteria phage T4)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379292(CHEMBL2011646)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of T4 arnN8l pseT 1 polynucleotide kinase assessed as inhibition of Salmon sperm DNA phosphorylation using [gamma32P]ATP by liquid scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDNA-directed DNA polymerase(Enterobacteria phage T4)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379292(CHEMBL2011646)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of T4 bacteriophage DNA polymerase assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDeoxyribonuclease-1(Bovine)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379293(CHEMBL2011648)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of bovine deoxyribonuclease 1 using [3H]-labelled DNA after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPolynucleotide kinase(Enterobacteria phage T4)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379293(CHEMBL2011648)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of T4 arnN8l pseT 1 polynucleotide kinase assessed as inhibition of Salmon sperm DNA phosphorylation using [gamma32P]ATP by liquid scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDNA-directed DNA/RNA polymerase mu(Human)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379292(CHEMBL2011646)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human His-tagged recombinant DNA polymerase mu expressed in Escherichia coli BL21 assessed as inhibition of incorporation of dTTP into ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDNA polymerase lambda(Human)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379292(CHEMBL2011646)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human recombinant His-tagged DNA polymerase lambda expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDNA polymerase beta(Rat)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379292(CHEMBL2011646)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of rat DNA polymerase beta expressed in Escherichia coli JMpbeta5 assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDNA polymerase kappa(Human)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379292(CHEMBL2011646)
Affinity DataKi:  9.85E+3nMAssay Description:Competitive inhibition of human C-terminal-His6-tagged DNA polymerase kappa expressed in Escherichia coli using dTTP as substrate by Dixon plot analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDNA polymerase kappa(Human)
Science University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50379292(CHEMBL2011646)
Affinity DataKi:  1.81E+4nMAssay Description:Non-competitive inhibition of human C-terminal-His6-tagged DNA polymerase kappa expressed in Escherichia coli using ploy(dA)/oligo(dT)18 as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed