Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 8239
TargetCarbonic anhydrase 2(Human)
Ataturk University

LigandPNGBDBM237302(4-Methyl-N-(2-nitrophenyl) benzenesulfonamide (7))
Affinity DataIC50: 103nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ataturk University

LigandPNGBDBM237304(N-(4-cyanophenyl)-4-methylbenzenesulfonamide (10))
Affinity DataIC50: 120nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ataturk University

LigandPNGBDBM237305(4-Methyl-N-(4-nitrophenyl) benzenesulfonamide (11))
Affinity DataIC50: 139nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ataturk University

LigandPNGBDBM237301(N-(2-cyanophenyl)-4-methylbenzenesulfonamide (6))
Affinity DataIC50: 213nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ataturk University

LigandPNGBDBM39340(MLS000069725 | cid_5336 | SMR000058213 | SULFAPYRI...)
Affinity DataIC50: 276nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Ataturk University

LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataIC50: 340nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ataturk University

LigandPNGBDBM50166571(4-amino-N-(pyrimidin-2-yl)benzenesulfonamide | 2-s...)
Affinity DataIC50: 341nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ataturk University

LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataIC50: 370nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Ataturk University

LigandPNGBDBM237300(4-Methyl-N-o-tolyl-benzenesulfonamide (5))
Affinity DataIC50: 407nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ataturk University

LigandPNGBDBM50044857(CHEMBL3311314 | CA inhibitor, 4)
Affinity DataIC50: 425nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ataturk University

LigandPNGBDBM45795(4-methyl-N-(2-naphthalenyl)benzenesulfonamide | ML...)
Affinity DataIC50: 612nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ataturk University

LigandPNGBDBM10857(aromatic sulfonamide compound 5 | CHEMBL21 | 4-ami...)
Affinity DataIC50: 628nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Ataturk University

LigandPNGBDBM10859(CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...)
Affinity DataIC50: 715nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Ataturk University

LigandPNGBDBM237303(N-(4-ethylphenyl)-4-methylbenzenesulfonamide (9))
Affinity DataIC50: 977nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ataturk University

LigandPNGBDBM237281(Carbonic anhydrase inhibitors (CAIs), 1)
Affinity DataIC50: 1.02E+3nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Ataturk University

LigandPNGBDBM237305(4-Methyl-N-(4-nitrophenyl) benzenesulfonamide (11))
Affinity DataIC50: 1.11E+3nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ataturk University

LigandPNGBDBM237305(4-Methyl-N-(4-nitrophenyl) benzenesulfonamide (11))
Affinity DataIC50: 1.13E+3nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Ataturk University

LigandPNGBDBM10857(aromatic sulfonamide compound 5 | CHEMBL21 | 4-ami...)
Affinity DataIC50: 1.21E+3nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Ataturk University

LigandPNGBDBM237304(N-(4-cyanophenyl)-4-methylbenzenesulfonamide (10))
Affinity DataIC50: 1.23E+3nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ataturk University

LigandPNGBDBM237304(N-(4-cyanophenyl)-4-methylbenzenesulfonamide (10))
Affinity DataIC50: 1.48E+3nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Ataturk University

LigandPNGBDBM237302(4-Methyl-N-(2-nitrophenyl) benzenesulfonamide (7))
Affinity DataIC50: 4.71E+3nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ataturk University

LigandPNGBDBM237302(4-Methyl-N-(2-nitrophenyl) benzenesulfonamide (7))
Affinity DataIC50: 5.38E+3nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Ataturk University

LigandPNGBDBM237301(N-(2-cyanophenyl)-4-methylbenzenesulfonamide (6))
Affinity DataIC50: 8.43E+3nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Ataturk University

LigandPNGBDBM50166571(4-amino-N-(pyrimidin-2-yl)benzenesulfonamide | 2-s...)
Affinity DataIC50: 1.16E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Ataturk University

LigandPNGBDBM50428400([(4-Methylphenyl)Sulfonyl]Phenylamine | CHEMBL1826...)
Affinity DataIC50: 1.34E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ataturk University

LigandPNGBDBM50428400([(4-Methylphenyl)Sulfonyl]Phenylamine | CHEMBL1826...)
Affinity DataIC50: 1.43E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Ataturk University

LigandPNGBDBM39340(MLS000069725 | cid_5336 | SMR000058213 | SULFAPYRI...)
Affinity DataIC50: 1.55E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ataturk University

LigandPNGBDBM237301(N-(2-cyanophenyl)-4-methylbenzenesulfonamide (6))
Affinity DataIC50: 1.82E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Ataturk University

LigandPNGBDBM10859(CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...)
Affinity DataIC50: 1.90E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ataturk University

LigandPNGBDBM10859(CHEMBL574 | 4-methylbenzene-1-sulfonamide | aromat...)
Affinity DataIC50: 2.21E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Ataturk University

LigandPNGBDBM237281(Carbonic anhydrase inhibitors (CAIs), 1)
Affinity DataIC50: 2.43E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ataturk University

LigandPNGBDBM50166571(4-amino-N-(pyrimidin-2-yl)benzenesulfonamide | 2-s...)
Affinity DataIC50: 2.62E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Ataturk University

LigandPNGBDBM237303(N-(4-ethylphenyl)-4-methylbenzenesulfonamide (9))
Affinity DataIC50: 2.65E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ataturk University

LigandPNGBDBM39340(MLS000069725 | cid_5336 | SMR000058213 | SULFAPYRI...)
Affinity DataIC50: 2.84E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Ataturk University

LigandPNGBDBM237300(4-Methyl-N-o-tolyl-benzenesulfonamide (5))
Affinity DataIC50: 2.96E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Ataturk University

LigandPNGBDBM50044857(CHEMBL3311314 | CA inhibitor, 4)
Affinity DataIC50: 3.22E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ataturk University

LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataIC50: 3.62E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 6(Human)
Ataturk University

LigandPNGBDBM45795(4-methyl-N-(2-naphthalenyl)benzenesulfonamide | ML...)
Affinity DataIC50: 4.24E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ataturk University

LigandPNGBDBM10857(aromatic sulfonamide compound 5 | CHEMBL21 | 4-ami...)
Affinity DataIC50: 4.29E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ataturk University

LigandPNGBDBM237281(Carbonic anhydrase inhibitors (CAIs), 1)
Affinity DataIC50: 5.00E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ataturk University

LigandPNGBDBM237300(4-Methyl-N-o-tolyl-benzenesulfonamide (5))
Affinity DataIC50: 1.48E+5nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ataturk University

LigandPNGBDBM50428400([(4-Methylphenyl)Sulfonyl]Phenylamine | CHEMBL1826...)
Affinity DataIC50: 2.10E+5nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ataturk University

LigandPNGBDBM50044857(CHEMBL3311314 | CA inhibitor, 4)
Affinity DataIC50: 2.49E+5nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ataturk University

LigandPNGBDBM45795(4-methyl-N-(2-naphthalenyl)benzenesulfonamide | ML...)
Affinity DataIC50: 3.22E+5nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ataturk University

LigandPNGBDBM237303(N-(4-ethylphenyl)-4-methylbenzenesulfonamide (9))
Affinity DataIC50: 4.48E+5nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed