Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50034629
TargetIntegrin alpha-IIb/beta-3(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50004058(N-(butylsulfonyl)-O-(4-piperidin-4-ylbutyl)-L-tyro...)
Affinity DataEC50:  13.6nMAssay Description:Inhibition of integrin alpha2bbeta3-mediated platelet aggregation in human TRAP-6-activated whole blood for 6 mins by impedence-based aggregometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50365350(CHEMBL1956154)
Affinity DataEC50:  40.8nMAssay Description:Inhibition of integrin alpha2bbeta3-mediated platelet aggregation in human TRAP-6-activated whole blood for 6 mins by impedence-based aggregometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50365352(CHEMBL1956152)
Affinity DataEC50:  276nMAssay Description:Inhibition of integrin alpha2bbeta3-mediated platelet aggregation in human TRAP-6-activated whole blood for 6 mins by impedence-based aggregometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50365354(CHEMBL1956150)
Affinity DataEC50:  7.80nMAssay Description:Inhibition of integrin alpha2bbeta3-mediated platelet aggregation in human TRAP-6-activated whole blood for 6 mins by impedence-based aggregometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50091737(2-Benzenesulfonylamino-3-[4-(2-piperidin-4-yl-etho...)
Affinity DataIC50: 0.810nMAssay Description:Displacement of extracellular matrix protein fibrinogen from human integrin alpha2bbeta3 after 1 hr by competitive ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50004058(N-(butylsulfonyl)-O-(4-piperidin-4-ylbutyl)-L-tyro...)
Affinity DataIC50: 0.950nMAssay Description:Displacement of extracellular matrix protein fibrinogen from human integrin alpha2bbeta3 after 1 hr by competitive ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50365354(CHEMBL1956150)
Affinity DataIC50: 1.20nMAssay Description:Displacement of extracellular matrix protein fibrinogen from human integrin alpha2bbeta3 after 1 hr by competitive ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50365350(CHEMBL1956154)
Affinity DataIC50: 3.30nMAssay Description:Displacement of extracellular matrix protein fibrinogen from human integrin alpha2bbeta3 after 1 hr by competitive ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50365346(CHEMBL1956158)
Affinity DataIC50: 4.40nMAssay Description:Displacement of extracellular matrix protein fibrinogen from human integrin alpha2bbeta3 after 1 hr by competitive ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50365353(CHEMBL1956151)
Affinity DataIC50: 6.30nMAssay Description:Displacement of extracellular matrix protein fibrinogen from human integrin alpha2bbeta3 after 1 hr by competitive ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50365352(CHEMBL1956152)
Affinity DataIC50: 22.7nMAssay Description:Displacement of extracellular matrix protein fibrinogen from human integrin alpha2bbeta3 after 1 hr by competitive ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50365348(CHEMBL1956156)
Affinity DataIC50: 62.5nMAssay Description:Displacement of extracellular matrix protein fibrinogen from human integrin alpha2bbeta3 after 1 hr by competitive ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50365351(CHEMBL1956153)
Affinity DataIC50: 136nMAssay Description:Displacement of extracellular matrix protein fibrinogen from human integrin alpha2bbeta3 after 1 hr by competitive ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50365349(CHEMBL1956155)
Affinity DataIC50: 1.15E+3nMAssay Description:Displacement of extracellular matrix protein fibrinogen from human integrin alpha2bbeta3 after 1 hr by competitive ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50365347(CHEMBL1956157)
Affinity DataIC50: 1.32E+3nMAssay Description:Displacement of extracellular matrix protein fibrinogen from human integrin alpha2bbeta3 after 1 hr by competitive ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed