Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50040842
TargetSodium-dependent dopamine transporter(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50401015(CHEMBL1947086)
Affinity DataKd:  9nMAssay Description:Binding affinity to rat DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50296782(CHEMBL538876 | PE2I | (1R,2S,3S,5S)-methyl 8-((E)-...)
Affinity DataKd:  4nMAssay Description:Binding affinity to rat DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50296249((1R,2S,3S,5S)-methyl 8-(4-fluorobut-2-ynyl)-3-p-to...)
Affinity DataIC50: 1.93nMAssay Description:Displacement of [3H]WIN35,428 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50296249((1R,2S,3S,5S)-methyl 8-(4-fluorobut-2-ynyl)-3-p-to...)
Affinity DataIC50: 3.26nMAssay Description:Displacement of [3H]DA from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50296249((1R,2S,3S,5S)-methyl 8-(4-fluorobut-2-ynyl)-3-p-to...)
Affinity DataIC50: 22.5nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50296249((1R,2S,3S,5S)-methyl 8-(4-fluorobut-2-ynyl)-3-p-to...)
Affinity DataIC50: 31.0nMAssay Description:Displacement of [3H]NE from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50296249((1R,2S,3S,5S)-methyl 8-(4-fluorobut-2-ynyl)-3-p-to...)
Affinity DataIC50: 108nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50296249((1R,2S,3S,5S)-methyl 8-(4-fluorobut-2-ynyl)-3-p-to...)
Affinity DataIC50: 240nMAssay Description:Displacement of [3H]5-HT from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50401014(CHEMBL2206307)
Affinity DataKi:  8nMAssay Description:Binding affinity to DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed