Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50040841
TargetPeroxisome proliferator-activated receptor alpha(Human)
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL
LigandPNGBDBM28762((2R)-2-(4-{2-[1,3-benzoxazol-2-yl(heptyl)amino]eth...)
Affinity DataEC50:  3nMAssay Description:Agonist activity at human GAL4-fused PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL
LigandPNGBDBM50401013(CHEMBL477312)
Affinity DataEC50:  90nMAssay Description:Agonist activity at human GAL4-fused PPARdelta ligand binding domain expressed in COS-1 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL
LigandPNGBDBM50401012(CHEMBL2206302)
Affinity DataEC50:  130nMAssay Description:Agonist activity at human GAL4-fused PPARdelta ligand binding domain expressed in COS-1 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL
LigandPNGBDBM50401011(CHEMBL2206303)
Affinity DataEC50:  850nMAssay Description:Agonist activity at human GAL4-fused PPARdelta ligand binding domain expressed in COS-1 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL
LigandPNGBDBM50401010(CHEMBL2206304)
Affinity DataEC50:  570nMAssay Description:Agonist activity at human GAL4-fused PPARdelta ligand binding domain expressed in COS-1 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL
LigandPNGBDBM50085041({4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]...)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human GAL4-fused PPARdelta ligand binding domain expressed in COS-1 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor gamma(Human)
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL
LigandPNGBDBM28762((2R)-2-(4-{2-[1,3-benzoxazol-2-yl(heptyl)amino]eth...)
Affinity DataKd:  270nMAssay Description:Binding affinity to PPARgamma ligand binding domain by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor gamma(Human)
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL
LigandPNGBDBM28763((2S)-2-(4-{2-[1,3-benzoxazol-2-yl(heptyl)amino]eth...)
Affinity DataKd:  2.00E+3nMAssay Description:Binding affinity to PPARgamma ligand binding domain by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL
LigandPNGBDBM50401013(CHEMBL477312)
Affinity DataKd:  4.50E+3nMAssay Description:Binding affinity to PPARgamma ligand binding domain by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor gamma(Human)
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL
LigandPNGBDBM50401012(CHEMBL2206302)
Affinity DataKd:  1.50E+3nMAssay Description:Binding affinity to PPARgamma ligand binding domain by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL
LigandPNGBDBM50401011(CHEMBL2206303)
Affinity DataKd:  3.30E+3nMAssay Description:Binding affinity to PPARgamma ligand binding domain by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL
LigandPNGBDBM50401010(CHEMBL2206304)
Affinity DataKd:  7.70E+3nMAssay Description:Binding affinity to PPARgamma ligand binding domain by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL
LigandPNGBDBM28681(cid_5281055 | [3H]rosiglitazone | CHEMBL121 | ROSI...)
Affinity DataKd:  120nMAssay Description:Binding affinity to PPARgamma ligand binding domain by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL
LigandPNGBDBM28681(cid_5281055 | [3H]rosiglitazone | CHEMBL121 | ROSI...)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human GAL4-fused PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL
LigandPNGBDBM28763((2S)-2-(4-{2-[1,3-benzoxazol-2-yl(heptyl)amino]eth...)
Affinity DataEC50:  56nMAssay Description:Agonist activity at human GAL4-fused PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL
LigandPNGBDBM24566(JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at human GAL4-fused PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor gamma(Human)
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL
LigandPNGBDBM50401008(CHEMBL2206306)
Affinity DataEC50:  1.70E+3nMAssay Description:Agonist activity at human GAL4-fused PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL
LigandPNGBDBM50401009(CHEMBL2206305)
Affinity DataEC50:  2.70E+3nMAssay Description:Agonist activity at human GAL4-fused PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL
LigandPNGBDBM50401010(CHEMBL2206304)
Affinity DataEC50:  800nMAssay Description:Agonist activity at human GAL4-fused PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL
LigandPNGBDBM50401011(CHEMBL2206303)
Affinity DataEC50:  2.30E+3nMAssay Description:Agonist activity at human GAL4-fused PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL
LigandPNGBDBM50401012(CHEMBL2206302)
Affinity DataEC50:  150nMAssay Description:Agonist activity at human GAL4-fused PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL
LigandPNGBDBM50401013(CHEMBL477312)
Affinity DataEC50:  110nMAssay Description:Agonist activity at human GAL4-fused PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor gamma(Human)
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL
LigandPNGBDBM28763((2S)-2-(4-{2-[1,3-benzoxazol-2-yl(heptyl)amino]eth...)
Affinity DataEC50:  590nMAssay Description:Agonist activity at human GAL4-fused PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL
LigandPNGBDBM28762((2R)-2-(4-{2-[1,3-benzoxazol-2-yl(heptyl)amino]eth...)
Affinity DataEC50:  70nMAssay Description:Agonist activity at human GAL4-fused PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor alpha(Human)
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL
LigandPNGBDBM50401013(CHEMBL477312)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human GAL4-fused PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL
LigandPNGBDBM50401009(CHEMBL2206305)
Affinity DataEC50:  1.72E+3nMAssay Description:Agonist activity at human GAL4-fused PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL
LigandPNGBDBM50401010(CHEMBL2206304)
Affinity DataEC50:  122nMAssay Description:Agonist activity at human GAL4-fused PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL
LigandPNGBDBM50401011(CHEMBL2206303)
Affinity DataEC50:  620nMAssay Description:Agonist activity at human GAL4-fused PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL
LigandPNGBDBM50401012(CHEMBL2206302)
Affinity DataEC50:  25nMAssay Description:Agonist activity at human GAL4-fused PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL
LigandPNGBDBM28681(cid_5281055 | [3H]rosiglitazone | CHEMBL121 | ROSI...)
Affinity DataKi:  74nMAssay Description:Displacement of [3H]rosiglitazone from N-terminal His-tagged human PPARgamma ligand binding domain expressed in Escherichia coli BL21 DE3 cells by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL
LigandPNGBDBM28762((2R)-2-(4-{2-[1,3-benzoxazol-2-yl(heptyl)amino]eth...)
Affinity DataKi:  88nMAssay Description:Displacement of [3H]rosiglitazone from N-terminal His-tagged human PPARgamma ligand binding domain expressed in Escherichia coli BL21 DE3 cells by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor gamma(Human)
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL
LigandPNGBDBM28763((2S)-2-(4-{2-[1,3-benzoxazol-2-yl(heptyl)amino]eth...)
Affinity DataKi:  971nMAssay Description:Displacement of [3H]rosiglitazone from N-terminal His-tagged human PPARgamma ligand binding domain expressed in Escherichia coli BL21 DE3 cells by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed