Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50034227
TargetP2X purinoceptor 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359218(CHEMBL1923313)
Affinity DataIC50: 24nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359221(CHEMBL1923316)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359223(CHEMBL1923318)
Affinity DataIC50: 28nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359225(CHEMBL1923320)
Affinity DataIC50: 39nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359227(CHEMBL1923322)
Affinity DataIC50: 45nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359231(CHEMBL1923323)
Affinity DataIC50: 50nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359219(CHEMBL1923314)
Affinity DataIC50: 52nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359230(CHEMBL1923326)
Affinity DataIC50: 55nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359212(CHEMBL1923307)
Affinity DataIC50: 85nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359217(CHEMBL1923312)
Affinity DataIC50: 91nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359229(CHEMBL1923325)
Affinity DataIC50: 95nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359220(CHEMBL1923315)
Affinity DataIC50: 101nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359222(CHEMBL1923317)
Affinity DataIC50: 104nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359211(CHEMBL1923306)
Affinity DataIC50: 107nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359214(CHEMBL1923309)
Affinity DataIC50: 108nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359224(CHEMBL1923319)
Affinity DataIC50: 110nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359212(CHEMBL1923307)
Affinity DataIC50: 121nMAssay Description:Antagonist activity at P2X7 receptor in rat whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359226(CHEMBL1923321)
Affinity DataIC50: 137nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359204(CHEMBL1923299)
Affinity DataIC50: 178nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359207(CHEMBL1923302)
Affinity DataIC50: 237nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359206(CHEMBL1923301)
Affinity DataIC50: 269nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359215(CHEMBL1923310)
Affinity DataIC50: 276nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359213(CHEMBL1923308)
Affinity DataIC50: 388nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359216(CHEMBL1923311)
Affinity DataIC50: 700nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359209(CHEMBL1923304)
Affinity DataIC50: 845nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359208(CHEMBL1923303)
Affinity DataIC50: 870nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359205(CHEMBL1923300)
Affinity DataIC50: 937nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359210(CHEMBL1923305)
Affinity DataIC50: 1.04E+3nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359228(CHEMBL1923324)
Affinity DataIC50: 1.94E+3nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed