Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50034226
TargetBeta-secretase 1(Human)
Research Informatics & Integrative Genomics

Curated by ChEMBL
LigandPNGBDBM50359203(CHEMBL1923297)
Affinity DataIC50: 25nMAssay Description:Inhibition of human BACE1-mediated amyloid beta TOT secretion in human SKNBE2 cells expressing human APP695 after 18 hrs by sandwich alphalisa assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Research Informatics & Integrative Genomics

Curated by ChEMBL
LigandPNGBDBM50359203(CHEMBL1923297)
Affinity DataIC50: 28nMAssay Description:Inhibition of human BACE1-mediated amyloid beta 42 secretion in human SKNBE2 cells expressing human APP695 after 18 hrs by sandwich alphalisa assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Research Informatics & Integrative Genomics

Curated by ChEMBL
LigandPNGBDBM50359198(CHEMBL1923160)
Affinity DataIC50: 36nMAssay Description:Inhibition of human BACE1-mediated amyloid beta 42 secretion in human SKNBE2 cells expressing human APP695 after 18 hrs by sandwich alphalisa assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Research Informatics & Integrative Genomics

Curated by ChEMBL
LigandPNGBDBM50359198(CHEMBL1923160)
Affinity DataIC50: 37nMAssay Description:Inhibition of human BACE1-mediated amyloid beta TOT secretion in human SKNBE2 cells expressing human APP695 after 18 hrs by sandwich alphalisa assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Research Informatics & Integrative Genomics

Curated by ChEMBL
LigandPNGBDBM50359203(CHEMBL1923297)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant BACE1 using fluorescent Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dnp)-OH peptide as substrate after 1 hr by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Research Informatics & Integrative Genomics

Curated by ChEMBL
LigandPNGBDBM50359200(CHEMBL1923295)
Affinity DataIC50: 68nMAssay Description:Inhibition of human BACE1-mediated amyloid beta 42 secretion in human SKNBE2 cells expressing human APP695 after 18 hrs by sandwich alphalisa assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Research Informatics & Integrative Genomics

Curated by ChEMBL
LigandPNGBDBM50359196(CHEMBL1923158)
Affinity DataIC50: 78nMAssay Description:Inhibition of human BACE1-mediated amyloid beta TOT secretion in human SKNBE2 cells expressing human APP695 after 18 hrs by sandwich alphalisa assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Research Informatics & Integrative Genomics

Curated by ChEMBL
LigandPNGBDBM50359200(CHEMBL1923295)
Affinity DataIC50: 79nMAssay Description:Inhibition of human BACE1-mediated amyloid beta TOT secretion in human SKNBE2 cells expressing human APP695 after 18 hrs by sandwich alphalisa assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Research Informatics & Integrative Genomics

Curated by ChEMBL
LigandPNGBDBM50359196(CHEMBL1923158)
Affinity DataIC50: 98nMAssay Description:Inhibition of human BACE1-mediated amyloid beta 42 secretion in human SKNBE2 cells expressing human APP695 after 18 hrs by sandwich alphalisa assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Research Informatics & Integrative Genomics

Curated by ChEMBL
LigandPNGBDBM50359202(CHEMBL1921816)
Affinity DataIC50: 107nMAssay Description:Inhibition of human BACE1-mediated amyloid beta TOT secretion in human SKNBE2 cells expressing human APP695 after 18 hrs by sandwich alphalisa assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Research Informatics & Integrative Genomics

Curated by ChEMBL
LigandPNGBDBM50359202(CHEMBL1921816)
Affinity DataIC50: 115nMAssay Description:Inhibition of human BACE1-mediated amyloid beta 42 secretion in human SKNBE2 cells expressing human APP695 after 18 hrs by sandwich alphalisa assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Research Informatics & Integrative Genomics

Curated by ChEMBL
LigandPNGBDBM50359199(CHEMBL1923294)
Affinity DataIC50: 151nMAssay Description:Inhibition of human BACE1-mediated amyloid beta TOT secretion in human SKNBE2 cells expressing human APP695 after 18 hrs by sandwich alphalisa assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Research Informatics & Integrative Genomics

Curated by ChEMBL
LigandPNGBDBM50359199(CHEMBL1923294)
Affinity DataIC50: 186nMAssay Description:Inhibition of human BACE1-mediated amyloid beta 42 secretion in human SKNBE2 cells expressing human APP695 after 18 hrs by sandwich alphalisa assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Research Informatics & Integrative Genomics

Curated by ChEMBL
LigandPNGBDBM50359198(CHEMBL1923160)
Affinity DataIC50: 324nMAssay Description:Inhibition of human recombinant BACE1 using fluorescent Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dnp)-OH peptide as substrate after 1 hr by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Research Informatics & Integrative Genomics

Curated by ChEMBL
LigandPNGBDBM50359196(CHEMBL1923158)
Affinity DataIC50: 447nMAssay Description:Inhibition of human recombinant BACE1 using fluorescent Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dnp)-OH peptide as substrate after 1 hr by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Research Informatics & Integrative Genomics

Curated by ChEMBL
LigandPNGBDBM50359202(CHEMBL1921816)
Affinity DataIC50: 550nMAssay Description:Inhibition of human recombinant BACE1 using fluorescent Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dnp)-OH peptide as substrate after 1 hr by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Research Informatics & Integrative Genomics

Curated by ChEMBL
LigandPNGBDBM50359199(CHEMBL1923294)
Affinity DataIC50: 813nMAssay Description:Inhibition of human recombinant BACE1 using fluorescent Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dnp)-OH peptide as substrate after 1 hr by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Research Informatics & Integrative Genomics

Curated by ChEMBL
LigandPNGBDBM50359201(CHEMBL1923296)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of human BACE1-mediated amyloid beta TOT secretion in human SKNBE2 cells expressing human APP695 after 18 hrs by sandwich alphalisa assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Research Informatics & Integrative Genomics

Curated by ChEMBL
LigandPNGBDBM50359201(CHEMBL1923296)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of human BACE1-mediated amyloid beta 42 secretion in human SKNBE2 cells expressing human APP695 after 18 hrs by sandwich alphalisa assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Research Informatics & Integrative Genomics

Curated by ChEMBL
LigandPNGBDBM50359200(CHEMBL1923295)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of human recombinant BACE1 using fluorescent Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dnp)-OH peptide as substrate after 1 hr by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Research Informatics & Integrative Genomics

Curated by ChEMBL
LigandPNGBDBM50359201(CHEMBL1923296)
Affinity DataIC50: 7.08E+3nMAssay Description:Inhibition of human recombinant BACE1 using fluorescent Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dnp)-OH peptide as substrate after 1 hr by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Research Informatics & Integrative Genomics

Curated by ChEMBL
LigandPNGBDBM50359197(CHEMBL1923159)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human BACE1-mediated amyloid beta TOT secretion in human SKNBE2 cells expressing human APP695 after 18 hrs by sandwich alphalisa assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Research Informatics & Integrative Genomics

Curated by ChEMBL
LigandPNGBDBM50359197(CHEMBL1923159)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human BACE1-mediated amyloid beta 42 secretion in human SKNBE2 cells expressing human APP695 after 18 hrs by sandwich alphalisa assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Research Informatics & Integrative Genomics

Curated by ChEMBL
LigandPNGBDBM50359197(CHEMBL1923159)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant BACE1 using fluorescent Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dnp)-OH peptide as substrate after 1 hr by spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed