Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50034220
TargetMonoglyceride lipase(Rat)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50359050(CHEMBL1922513)
Affinity DataIC50: 59nMAssay Description:Inhibition of rat recombinant N-terminal his-tagged MAGL expressed in Escherichia coli DH5alpha assessed as 2-oleoylglycerol hydrolysis after 10 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50359049(CHEMBL1922512)
Affinity DataIC50: 88nMAssay Description:Inhibition of rat recombinant N-terminal his-tagged MAGL expressed in Escherichia coli DH5alpha assessed as 2-oleoylglycerol hydrolysis after 10 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50359049(CHEMBL1922512)
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant MAGL assessed as inhibition of 2-oleoylglycerol hydrolysis preincubated for 10 mins by LC/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50359051(CHEMBL1922515)
Affinity DataIC50: 410nMAssay Description:Inhibition of human recombinant MAGL assessed as [3H]oleoylglycerol hydrolysis after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50359050(CHEMBL1922513)
Affinity DataIC50: 660nMAssay Description:Inhibition of human recombinant MAGL assessed as inhibition of 2-oleoylglycerol hydrolysis preincubated for 10 mins by LC/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50359049(CHEMBL1922512)
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of human recombinant MAGL assessed as [3H]oleoylglycerol hydrolysis after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50359050(CHEMBL1922513)
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of human recombinant MAGL assessed as [3H]oleoylglycerol hydrolysis after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50359049(CHEMBL1922512)
Affinity DataIC50: 1.89E+4nMAssay Description:Inhibition of human recombinant FAAH assessed as conversion of [3H]AEA to [3H]ethanolamine after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50359051(CHEMBL1922515)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant FAAH assessed as conversion of [3H]AEA to [3H]ethanolamine after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50359053(CHEMBL1922518)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of human recombinant FAAH assessed as conversion of [3H]AEA to [3H]ethanolamine after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50359050(CHEMBL1922513)
Affinity DataIC50: 3.52E+4nMAssay Description:Inhibition of human recombinant FAAH assessed as conversion of [3H]AEA to [3H]ethanolamine after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50359052(CHEMBL1922517)
Affinity DataIC50: 4.47E+4nMAssay Description:Inhibition of human recombinant FAAH assessed as conversion of [3H]AEA to [3H]ethanolamine after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50359053(CHEMBL1922518)
Affinity DataIC50: 6.79E+4nMAssay Description:Inhibition of human recombinant MAGL assessed as [3H]oleoylglycerol hydrolysis after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50359054(CHEMBL1922521)
Affinity DataIC50: 1.29E+5nMAssay Description:Inhibition of human recombinant FAAH assessed as conversion of [3H]AEA to [3H]ethanolamine after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50359052(CHEMBL1922517)
Affinity DataIC50: 2.75E+5nMAssay Description:Inhibition of human recombinant MAGL assessed as [3H]oleoylglycerol hydrolysis after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50359055(CHEMBL1922522)
Affinity DataIC50: 3.09E+5nMAssay Description:Inhibition of human recombinant FAAH assessed as conversion of [3H]AEA to [3H]ethanolamine after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed