Compile Data Set for Download or QSAR
Report error Found 108 Enz. Inhib. hit(s) with all data for entry = 50034171
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358214(CHEMBL454617)
Affinity DataIC50: 40nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358213(CHEMBL1922219 | US8846696, (2R3S)-3-{9-Isopropyl-6...)
Affinity DataIC50: 107nMAssay Description:Inhibition of CDK9 in human HT29 cells assessed as reduction in RNA polymerase 2 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358213(CHEMBL1922219 | US8846696, (2R3S)-3-{9-Isopropyl-6...)
Affinity DataIC50: 110nMAssay Description:Inhibition of CDK9/cyclin T1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358211(CHEMBL1922212 | US8846696, (3S)-3-{9-Isopropyl-6-[...)
Affinity DataIC50: 160nMAssay Description:Inhibition of CDK9/cyclin T1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358220(CHEMBL455389)
Affinity DataIC50: 180nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358210(CHEMBL1922123 | US8846696, (3R)-3-{9-Isopropyl-6-[...)
Affinity DataIC50: 210nMAssay Description:Inhibition of CDK9/cyclin T1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358212(CHEMBL1922218 | US8846696, (2S3R)-3-{9-Isopropyl-6...)
Affinity DataIC50: 260nMAssay Description:Inhibition of CDK9/cyclin T1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358225(CHEMBL1922199)
Affinity DataIC50: 390nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358212(CHEMBL1922218 | US8846696, (2S3R)-3-{9-Isopropyl-6...)
Affinity DataIC50: 500nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 520nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358215(CHEMBL1922114)
Affinity DataIC50: 550nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358238(CHEMBL1922213)
Affinity DataIC50: 690nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358224(CHEMBL455641)
Affinity DataIC50: 740nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358221(CHEMBL1922120 | US8846696, (3RS,4R)-4-{9-Isopropyl...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358239(CHEMBL1922214)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358216(CHEMBL1922115)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358226(CHEMBL1922200)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358213(CHEMBL1922219 | US8846696, (2R3S)-3-{9-Isopropyl-6...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of CDK7 in human HT29 cells assessed as reduction in RNA polymerase 2 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358213(CHEMBL1922219 | US8846696, (2R3S)-3-{9-Isopropyl-6...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358235(CHEMBL1922209 | US8846696, (3RS,4S)-4-{9-Isopropyl...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358223(CHEMBL1922122 | US8846696, (3RS,4R)-4-{9-Isopropyl...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358242(CHEMBL1922217)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358222(CHEMBL1922121 | US8846696, (3RS,4R)-4-{9-Isopropyl...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358213(CHEMBL1922219 | US8846696, (2R3S)-3-{9-Isopropyl-6...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of CDK1/cyclin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358218(CHEMBL1922117)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358211(CHEMBL1922212 | US8846696, (3S)-3-{9-Isopropyl-6-[...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358230(CHEMBL1922204)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358231(CHEMBL1922205)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358240(CHEMBL1922215)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358210(CHEMBL1922123 | US8846696, (3R)-3-{9-Isopropyl-6-[...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358232(CHEMBL1922206)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358236(CHEMBL1922210 | US8846696, (3RS,4S)-4-{9-Isopropyl...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358237(CHEMBL1922211 | US8846696, (3RS,4S)-4-{9-Isopropyl...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358228(CHEMBL1922202)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358229(CHEMBL1922203)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358217(CHEMBL1922116)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358214(CHEMBL454617)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of CDK1/cyclin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358219(CHEMBL1922118)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358234(CHEMBL1921805)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358241(CHEMBL1922216)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358227(CHEMBL1922201)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358211(CHEMBL1922212 | US8846696, (3S)-3-{9-Isopropyl-6-[...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of CDK1/cyclin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358212(CHEMBL1922218 | US8846696, (2S3R)-3-{9-Isopropyl-6...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of CDK1/cyclin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358233(CHEMBL1922207)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358210(CHEMBL1922123 | US8846696, (3R)-3-{9-Isopropyl-6-[...)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of CDK1/cyclin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358220(CHEMBL455389)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of CDK1/cyclin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358230(CHEMBL1922204)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of CDK1/cyclin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358242(CHEMBL1922217)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of CDK1/cyclin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358238(CHEMBL1922213)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of CDK1/cyclin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50358214(CHEMBL454617)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of ERK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
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