Compile Data Set for Download or QSAR
Report error Found 61 Enz. Inhib. hit(s) with all data for entry = 50034167
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50358186(CHEMBL1921956)
Affinity DataEC50:  6.40E+3nMAssay Description:Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50358180(CHEMBL1921852)
Affinity DataEC50:  226nMAssay Description:Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50358181(CHEMBL1921853)
Affinity DataEC50:  402nMAssay Description:Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50358182(CHEMBL1921854)
Affinity DataEC50:  765nMAssay Description:Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50358174(CHEMBL1921855)
Affinity DataEC50:  136nMAssay Description:Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50358183(CHEMBL1921948)
Affinity DataEC50:  1.80E+3nMAssay Description:Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50358175(CHEMBL1921950)
Affinity DataEC50:  179nMAssay Description:Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50358176(CHEMBL1921951)
Affinity DataEC50:  353nMAssay Description:Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50358177(CHEMBL1921952)
Affinity DataEC50:  104nMAssay Description:Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50358184(CHEMBL1921954)
Affinity DataEC50:  1.10E+3nMAssay Description:Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50358185(CHEMBL1921955)
Affinity DataEC50:  1.80E+3nMAssay Description:Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM55091(N-[3-chloranyl-4-[(1S,5R)-6,6-dimethyl-2,4-bis(oxi...)
Affinity DataEC50:  435nMAssay Description:Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM55086(N-[4-[1,3-bis(oxidanylidene)isoindol-2-yl]-3-chlor...)
Affinity DataEC50:  59.4nMAssay Description:Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM55087(VU0405623-1 | N-[3-chloranyl-4-[4-chloranyl-1,3-bi...)
Affinity DataEC50:  41.9nMAssay Description:Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50358178(CHEMBL1921959)
Affinity DataEC50:  370nMAssay Description:Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50358187(CHEMBL1921960)
Affinity DataEC50:  1.30E+3nMAssay Description:Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50358179(CHEMBL1921961)
Affinity DataEC50:  291nMAssay Description:Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50358179(CHEMBL1921961)
Affinity DataEC50:  1.70E+3nMAssay Description:Positive allosteric modulator activity at rat mGlu5 receptor expressed in human HEK293 at 10 uM by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50358179(CHEMBL1921961)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulator activity at human mGlu6 receptor at 10 uM by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50358179(CHEMBL1921961)
Affinity DataEC50:  2.90E+3nMAssay Description:Positive allosteric modulator activity at rat mGlu7 receptor at 10 uM by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM55085(N-[3-chloro-4-(2,5-dioxopyrrolidin-1-yl)phenyl]pyr...)
Affinity DataEC50:  6.20E+3nMAssay Description:Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50358177(CHEMBL1921952)
Affinity DataEC50:  105nMAssay Description:Positive allosteric modulator activity at rat mGlu4 receptor by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM55095(cid_46869952 | N-[3-chloranyl-4-[3-methyl-2,5-bis(...)
Affinity DataEC50:  536nMAssay Description:Positive allosteric modulator activity at rat mGlu4 receptor by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM55093(cid_46869951 | N-[3-chloro-4-(1,3-dioxo-2-azaspiro...)
Affinity DataEC50:  397nMAssay Description:Positive allosteric modulator activity at rat mGlu4 receptor by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM55091(N-[3-chloranyl-4-[(1S,5R)-6,6-dimethyl-2,4-bis(oxi...)
Affinity DataEC50:  686nMAssay Description:Positive allosteric modulator activity at rat mGlu4 receptor by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50358173(CHEMBL1921962)
Affinity DataEC50:  246nMAssay Description:Positive allosteric modulator activity at rat mGlu4 receptor by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50358179(CHEMBL1921961)
Affinity DataEC50:  376nMAssay Description:Positive allosteric modulator activity at rat mGlu4 receptor by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50358178(CHEMBL1921959)
Affinity DataEC50:  645nMAssay Description:Positive allosteric modulator activity at rat mGlu4 receptor by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM55087(VU0405623-1 | N-[3-chloranyl-4-[4-chloranyl-1,3-bi...)
Affinity DataEC50:  34.9nMAssay Description:Positive allosteric modulator activity at rat mGlu4 receptor by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM55086(N-[4-[1,3-bis(oxidanylidene)isoindol-2-yl]-3-chlor...)
Affinity DataEC50:  66.8nMAssay Description:Positive allosteric modulator activity at rat mGlu4 receptor by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM55094(N-[3-chloro-4-(2,5-dioxo-3-phenyl-1-pyrrolidinyl)p...)
Affinity DataEC50:  491nMAssay Description:Positive allosteric modulator activity at rat mGlu4 receptor by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50358176(CHEMBL1921951)
Affinity DataEC50:  201nMAssay Description:Positive allosteric modulator activity at rat mGlu4 receptor by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50358175(CHEMBL1921950)
Affinity DataEC50:  242nMAssay Description:Positive allosteric modulator activity at rat mGlu4 receptor by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50358174(CHEMBL1921855)
Affinity DataEC50:  165nMAssay Description:Positive allosteric modulator activity at rat mGlu4 receptor by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM55095(cid_46869952 | N-[3-chloranyl-4-[3-methyl-2,5-bis(...)
Affinity DataEC50:  771nMAssay Description:Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM55094(N-[3-chloro-4-(2,5-dioxo-3-phenyl-1-pyrrolidinyl)p...)
Affinity DataEC50:  674nMAssay Description:Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM55093(cid_46869951 | N-[3-chloro-4-(1,3-dioxo-2-azaspiro...)
Affinity DataEC50:  158nMAssay Description:Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM55092(cid_46869950 | N-[3-chloro-4-(3,3-dimethyl-2,5-dio...)
Affinity DataEC50:  1.40E+3nMAssay Description:Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50358173(CHEMBL1921962)
Affinity DataEC50:  287nMAssay Description:Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM55094(N-[3-chloro-4-(2,5-dioxo-3-phenyl-1-pyrrolidinyl)p...)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using 4-hydroxydiclofenac as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM55094(N-[3-chloro-4-(2,5-dioxo-3-phenyl-1-pyrrolidinyl)p...)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using acetaminophen as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM55094(N-[3-chloro-4-(2,5-dioxo-3-phenyl-1-pyrrolidinyl)p...)
Affinity DataIC50: 1.76E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50358179(CHEMBL1921961)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextrophan tartarate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50358174(CHEMBL1921855)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using 4-hydroxydiclofenac as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50358179(CHEMBL1921961)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using 4-hydroxydiclofenac as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM55093(cid_46869951 | N-[3-chloro-4-(1,3-dioxo-2-azaspiro...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using 4-hydroxydiclofenac as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM55093(cid_46869951 | N-[3-chloro-4-(1,3-dioxo-2-azaspiro...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50358179(CHEMBL1921961)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50293721(cid_44191096 | CHEMBL562551 | N-(4-chloro-3-methox...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using 4-hydroxydiclofenac as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50358174(CHEMBL1921855)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextrophan tartarate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
Displayed 1 to 50 (of 61 total ) | Next | Last >>
Jump to: