Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50034115
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM22372(Nordihydroguaiaretic Acid | CHEMBL313972 | 4-[(2S,...)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human 5-LOX in human PBML assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50357361(CHEMBL1917102)
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant human 5-LOX in human PBML assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM22369(CHEMBL122 | MK 0966 | 4-(4-methanesulfonylphenyl)-...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant COX2 expressed in Sf21 cells assessed as conversion of arachidonic acid to PGE2 preincubated for 15 mins measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50357356(CHEMBL1917097)
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant human 5-LOX in human PBML assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50357358(CHEMBL1917099)
Affinity DataIC50: 270nMAssay Description:Inhibition of human recombinant COX2 expressed in Sf21 cells assessed as conversion of arachidonic acid to PGE2 preincubated for 15 mins measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50357358(CHEMBL1917099)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant human 5-LOX in human PBML assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50357359(CHEMBL1917100)
Affinity DataIC50: 350nMAssay Description:Inhibition of recombinant human 5-LOX in human PBML assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50357357(CHEMBL1917098)
Affinity DataIC50: 360nMAssay Description:Inhibition of recombinant human 5-LOX in human PBML assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50357361(CHEMBL1917102)
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant COX2 expressed in Sf21 cells assessed as conversion of arachidonic acid to PGE2 preincubated for 15 mins measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50357360(CHEMBL1917101)
Affinity DataIC50: 680nMAssay Description:Inhibition of recombinant human 5-LOX in human PBML assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50357357(CHEMBL1917098)
Affinity DataIC50: 730nMAssay Description:Inhibition of human recombinant COX2 expressed in Sf21 cells assessed as conversion of arachidonic acid to PGE2 preincubated for 15 mins measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50357359(CHEMBL1917100)
Affinity DataIC50: 880nMAssay Description:Inhibition of human recombinant COX2 expressed in Sf21 cells assessed as conversion of arachidonic acid to PGE2 preincubated for 15 mins measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50357356(CHEMBL1917097)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant COX2 expressed in Sf21 cells assessed as conversion of arachidonic acid to PGE2 preincubated for 15 mins measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50357351(CHEMBL1917088)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant COX2 expressed in Sf21 cells assessed as conversion of arachidonic acid to PGE2 preincubated for 15 mins measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50357350(CHEMBL1917087)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human recombinant COX2 expressed in Sf21 cells assessed as conversion of arachidonic acid to PGE2 preincubated for 15 mins measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50357362(CHEMBL1917103)
Affinity DataIC50: 2.99E+3nMAssay Description:Inhibition of human recombinant COX2 expressed in Sf21 cells assessed as conversion of arachidonic acid to PGE2 preincubated for 15 mins measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50357362(CHEMBL1917103)
Affinity DataIC50: 3.09E+3nMAssay Description:Inhibition of recombinant human 5-LOX in human PBML assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50357354(CHEMBL1917086)
Affinity DataIC50: 3.45E+3nMAssay Description:Inhibition of recombinant human 5-LOX in human PBML assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50357363(CHEMBL1917105)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of recombinant human 5-LOX in human PBML assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50357355(CHEMBL1917092)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of recombinant human 5-LOX in human PBML assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50357352(CHEMBL1917090)
Affinity DataIC50: 6.05E+3nMAssay Description:Inhibition of recombinant human 5-LOX in human PBML assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50357351(CHEMBL1917088)
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of recombinant human 5-LOX in human PBML assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50357350(CHEMBL1917087)
Affinity DataIC50: 2.58E+4nMAssay Description:Inhibition of recombinant human 5-LOX in human PBML assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50357353(CHEMBL1917107)
Affinity DataIC50: 9.11E+4nMAssay Description:Inhibition of recombinant human 5-LOX in human PBML assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed