Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50034035
TargetOrexin receptor type 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50355815(CHEMBL1911942)
Affinity DataIC50: 3.30nMAssay Description:Antagonist activity at OX2R expressed in dihydrofolate reductase deficient CHO cells assessed as inhibition of orexin A-induced intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50355814(CHEMBL1911941)
Affinity DataIC50: 87nMAssay Description:Antagonist activity at OX2R expressed in dihydrofolate reductase deficient CHO cells assessed as inhibition of orexin A-induced intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50355813(CHEMBL1911940)
Affinity DataIC50: 130nMAssay Description:Antagonist activity at OX2R expressed in dihydrofolate reductase deficient CHO cells assessed as inhibition of orexin A-induced intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50419320(CHEMBL2092734)
Affinity DataIC50: 170nMAssay Description:Antagonist activity at OX2R expressed in dihydrofolate reductase deficient CHO cells assessed as inhibition of orexin A-induced intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50419321(CHEMBL2092888)
Affinity DataIC50: 220nMAssay Description:Antagonist activity at OX2R expressed in dihydrofolate reductase deficient CHO cells assessed as inhibition of orexin A-induced intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50355809(CHEMBL1911936)
Affinity DataIC50: 230nMAssay Description:Antagonist activity at OX2R expressed in dihydrofolate reductase deficient CHO cells assessed as inhibition of orexin A-induced intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50419320(CHEMBL2092734)
Affinity DataIC50: 280nMAssay Description:Antagonist activity at OX1R expressed in dihydrofolate reductase deficient CHO cells assessed as inhibition of orexin A-induced intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50355810(CHEMBL1911937)
Affinity DataIC50: 710nMAssay Description:Antagonist activity at OX2R expressed in dihydrofolate reductase deficient CHO cells assessed as inhibition of orexin A-induced intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50355812(CHEMBL1911939)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at OX2R expressed in dihydrofolate reductase deficient CHO cells assessed as inhibition of orexin A-induced intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50355815(CHEMBL1911942)
Affinity DataIC50: 1.50E+3nMAssay Description:Antagonist activity at OX1R expressed in dihydrofolate reductase deficient CHO cells assessed as inhibition of orexin A-induced intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50355809(CHEMBL1911936)
Affinity DataIC50: 1.60E+3nMAssay Description:Antagonist activity at OX1R expressed in dihydrofolate reductase deficient CHO cells assessed as inhibition of orexin A-induced intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50355814(CHEMBL1911941)
Affinity DataIC50: 1.60E+3nMAssay Description:Antagonist activity at OX1R expressed in dihydrofolate reductase deficient CHO cells assessed as inhibition of orexin A-induced intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50355813(CHEMBL1911940)
Affinity DataIC50: 2.30E+3nMAssay Description:Antagonist activity at OX1R expressed in dihydrofolate reductase deficient CHO cells assessed as inhibition of orexin A-induced intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50419321(CHEMBL2092888)
Affinity DataIC50: 2.50E+3nMAssay Description:Antagonist activity at OX1R expressed in dihydrofolate reductase deficient CHO cells assessed as inhibition of orexin A-induced intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50355810(CHEMBL1911937)
Affinity DataIC50: 6.30E+3nMAssay Description:Antagonist activity at OX1R expressed in dihydrofolate reductase deficient CHO cells assessed as inhibition of orexin A-induced intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50355812(CHEMBL1911939)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at OX1R expressed in dihydrofolate reductase deficient CHO cells assessed as inhibition of orexin A-induced intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed