Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50033969
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Shanghai Pharmaceutical Holding

Curated by ChEMBL
LigandPNGBDBM50354745(CHEMBL1834084)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human 11beta HSD1 expressed in HEK293 cells assessed as assessed as inhibition of [1,2-(n)3H]cortisone to [3H]-cortisol after 60 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Shanghai Pharmaceutical Holding

Curated by ChEMBL
LigandPNGBDBM50233538(3beta-hydroxy-11-oxoolean-12-en-30-oic acid | glyc...)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of human 11beta HSD1 expressed in HEK293 cells assessed as assessed as inhibition of [1,2-(n)3H]cortisone to [3H]-cortisol after 60 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Shanghai Pharmaceutical Holding

Curated by ChEMBL
LigandPNGBDBM32546(arylsulfonylpiperazine, 18)
Affinity DataIC50: 11nMAssay Description:Inhibition of human 11beta HSD1 expressed in HEK293 cells assessed as assessed as inhibition of [1,2-(n)3H]cortisone to [3H]-cortisol after 60 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Shanghai Pharmaceutical Holding

Curated by ChEMBL
LigandPNGBDBM32547(arylsulfonylpiperazine, 19)
Affinity DataIC50: 13nMAssay Description:Inhibition of human 11beta HSD1 expressed in HEK293 cells assessed as assessed as inhibition of [1,2-(n)3H]cortisone to [3H]-cortisol after 60 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Shanghai Pharmaceutical Holding

Curated by ChEMBL
LigandPNGBDBM50117901(2-[2-(3-Chloro-2-methyl-benzenesulfonylamino)-thia...)
Affinity DataIC50: 28.4nMAssay Description:Inhibition of human 11beta HSD1 expressed in HEK293 cells assessed as assessed as inhibition of [1,2-(n)3H]cortisone to [3H]-cortisol after 60 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Shanghai Pharmaceutical Holding

Curated by ChEMBL
LigandPNGBDBM50354740(CHEMBL1834080)
Affinity DataIC50: 28.8nMAssay Description:Inhibition of human 11beta HSD1 expressed in HEK293 cells assessed as assessed as inhibition of [1,2-(n)3H]cortisone to [3H]-cortisol after 60 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Shanghai Pharmaceutical Holding

Curated by ChEMBL
LigandPNGBDBM50354741(CHEMBL1834081)
Affinity DataIC50: 32.7nMAssay Description:Inhibition of human 11beta HSD1 expressed in HEK293 cells assessed as assessed as inhibition of [1,2-(n)3H]cortisone to [3H]-cortisol after 60 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Shanghai Pharmaceutical Holding

Curated by ChEMBL
LigandPNGBDBM50354746(CHEMBL1834085)
Affinity DataIC50: 41.3nMAssay Description:Inhibition of human 11beta HSD1 expressed in HEK293 cells assessed as assessed as inhibition of [1,2-(n)3H]cortisone to [3H]-cortisol after 60 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Shanghai Pharmaceutical Holding

Curated by ChEMBL
LigandPNGBDBM50354742(CHEMBL1834082)
Affinity DataIC50: 45nMAssay Description:Inhibition of human 11beta HSD1 expressed in HEK293 cells assessed as assessed as inhibition of [1,2-(n)3H]cortisone to [3H]-cortisol after 60 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Shanghai Pharmaceutical Holding

Curated by ChEMBL
LigandPNGBDBM72094(MLS000550742 | 1-(2,3-dihydroindol-1-yl)-2-[(5,6-d...)
Affinity DataIC50: 58.1nMAssay Description:Inhibition of human 11beta HSD1 expressed in HEK293 cells assessed as assessed as inhibition of [1,2-(n)3H]cortisone to [3H]-cortisol after 60 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Shanghai Pharmaceutical Holding

Curated by ChEMBL
LigandPNGBDBM50354743(CHEMBL1834083)
Affinity DataIC50: 66.7nMAssay Description:Inhibition of human 11beta HSD1 expressed in HEK293 cells assessed as assessed as inhibition of [1,2-(n)3H]cortisone to [3H]-cortisol after 60 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Shanghai Pharmaceutical Holding

Curated by ChEMBL
LigandPNGBDBM50354744(CHEMBL1379780)
Affinity DataIC50: 102nMAssay Description:Inhibition of human 11beta HSD1 expressed in HEK293 cells assessed as assessed as inhibition of [1,2-(n)3H]cortisone to [3H]-cortisol after 60 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Shanghai Pharmaceutical Holding

Curated by ChEMBL
LigandPNGBDBM72094(MLS000550742 | 1-(2,3-dihydroindol-1-yl)-2-[(5,6-d...)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of human 11beta HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed