Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50033794
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50351408(CHEMBL1819199)
Affinity DataIC50: 0.778nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction of [14C]-labeled AMG after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50351415(CHEMBL1819096)
Affinity DataIC50: 0.899nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction of [14C]-labeled AMG after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50351413(CHEMBL1819095)
Affinity DataIC50: 0.974nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction of [14C]-labeled AMG after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50351411(CHEMBL1819093)
Affinity DataIC50: 1.34nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction of [14C]-labeled AMG after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50351407(CHEMBL1819198)
Affinity DataIC50: 1.35nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction of [14C]-labeled AMG after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM20880(CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...)
Affinity DataIC50: 1.35nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction of [14C]-labeled AMG after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50351405(CHEMBL1819196)
Affinity DataIC50: 1.38nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction of [14C]-labeled AMG after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50351410(CHEMBL1819201)
Affinity DataIC50: 1.38nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction of [14C]-labeled AMG after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50351404(CHEMBL1819099)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction of [14C]-labeled AMG after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50351406(CHEMBL1819197)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction of [14C]-labeled AMG after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50351403(CHEMBL1819098)
Affinity DataIC50: 1.59nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction of [14C]-labeled AMG after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50351414(CHEMBL1817684)
Affinity DataIC50: 2.27nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction of [14C]-labeled AMG after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50351412(CHEMBL1819094)
Affinity DataIC50: 2.95nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction of [14C]-labeled AMG after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50351416(CHEMBL1819097)
Affinity DataIC50: 3.63nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction of [14C]-labeled AMG after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50351409(CHEMBL1819200)
Affinity DataIC50: 3.65nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as reduction of [14C]-labeled AMG after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed