Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50033793
TargetDipeptidyl peptidase 4(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50351399(CHEMBL1819089)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of DPP4 in human plasma assessed as formation of 7-amino-4-methylcoumarin from glycyl-L-proline 4-methylcoumaryl-7-amide by fluorescence a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM11695((2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}p...)
Affinity DataIC50: 0.580nMAssay Description:Inhibition of DPP4 in human plasma assessed as formation of 7-amino-4-methylcoumarin from glycyl-L-proline 4-methylcoumaryl-7-amide by fluorescence a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM16285(2-({6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-di...)
Affinity DataIC50: 1nMAssay Description:Inhibition of DPP4 in human plasma assessed as formation of 7-amino-4-methylcoumarin from glycyl-L-proline 4-methylcoumaryl-7-amide by fluorescence a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50351402(CHEMBL1819090)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of DPP4 in human plasma assessed as formation of 7-amino-4-methylcoumarin from glycyl-L-proline 4-methylcoumaryl-7-amide by fluorescence a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM11162(Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of DPP4 in human plasma assessed as formation of 7-amino-4-methylcoumarin from glycyl-L-proline 4-methylcoumaryl-7-amide by fluorescence a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50351401(CHEMBL1819091)
Affinity DataIC50: 26nMAssay Description:Inhibition of DPP4 in human plasma assessed as formation of 7-amino-4-methylcoumarin from glycyl-L-proline 4-methylcoumaryl-7-amide by fluorescence a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50351400(CHEMBL1819092)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of DPP4 in human plasma assessed as formation of 7-amino-4-methylcoumarin from glycyl-L-proline 4-methylcoumaryl-7-amide by fluorescence a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50351399(CHEMBL1819089)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50351399(CHEMBL1819089)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50351402(CHEMBL1819090)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to muscarinic receptor 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50351402(CHEMBL1819090)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to muscarinic receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50351402(CHEMBL1819090)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to muscarinic receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50351399(CHEMBL1819089)
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50351402(CHEMBL1819090)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50351402(CHEMBL1819090)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50351402(CHEMBL1819090)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50351402(CHEMBL1819090)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50351402(CHEMBL1819090)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C8More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50351402(CHEMBL1819090)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50351402(CHEMBL1819090)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes pre-incubated for 15 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50351402(CHEMBL1819090)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetXaa-Pro aminopeptidase 2(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50351402(CHEMBL1819090)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of aminopeptidase PMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50351402(CHEMBL1819090)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of prolyl oligopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50351402(CHEMBL1819090)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of FAPalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50351402(CHEMBL1819090)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50351402(CHEMBL1819090)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of DPP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50351402(CHEMBL1819090)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2A6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50351401(CHEMBL1819091)
Affinity DataKi:  0.0220nMAssay Description:Inhibition of CYP3A4 in human liver microsomes pre-incubated for 15 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50351399(CHEMBL1819089)
Affinity DataKi:  0.0260nMAssay Description:Inhibition of CYP3A4 in human liver microsomes pre-incubated for 15 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed