Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50040283
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50099491(cid_3392731 | CHEMBL21241 | 2-(4-{2-[3-Cyclohexyl-...)
Affinity DataEC50:  0.600nMAssay Description:Activation of PPARalpha transfected in HEK293 cells after 18 hrs by firefly luciferase reporter gene-based luminescence assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50085045(5-((4-((6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-...)
Affinity DataEC50:  400nMAssay Description:Activation of PPARgamma transfected in HEK293 cells after 18 hrs by firefly luciferase reporter gene-based luminescence assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391884(CHEMBL463574)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of sheep placental COX2 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391887(CHEMBL2147422)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of sheep placental COX2 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50006805(CHEMBL29097 | 3-(3-(tert-butylthio)-1-(4-chloroben...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of mPGES1 in IL-1beta treated human A549 cell microsomal membrane assessed as inhibition of PGE2 formation incubated for 15 mins before ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of ram seminal vesicle COX1 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | NS398 | NS-398 | N-(2-Cyclohexyloxy-4...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of sheep placental COX2 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Sheep)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391880(CHEMBL2147423)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of ram seminal vesicle COX1 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391884(CHEMBL463574)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of ram seminal vesicle COX1 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391890(CHEMBL2147420)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of ram seminal vesicle COX1 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391887(CHEMBL2147422)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of mPGES1 in IL-1beta treated human A549 cell microsomal membrane assessed as inhibition of PGE2 formation incubated for 15 mins before ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391890(CHEMBL2147420)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of sheep placental COX2 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391890(CHEMBL2147420)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of mPGES1 in IL-1beta treated human A549 cell microsomal membrane assessed as inhibition of PGE2 formation incubated for 15 mins before ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391880(CHEMBL2147423)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of sheep placental COX2 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391884(CHEMBL463574)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of mPGES1 in IL-1beta treated human A549 cell microsomal membrane assessed as inhibition of PGE2 formation incubated for 15 mins before ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391883(CHEMBL2147424)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of mPGES1 in IL-1beta treated human A549 cell microsomal membrane assessed as inhibition of PGE2 formation incubated for 15 mins before ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391880(CHEMBL2147423)
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of mPGES1 in IL-1beta treated human A549 cell microsomal membrane assessed as inhibition of PGE2 formation incubated for 15 mins before ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391887(CHEMBL2147422)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of ram seminal vesicle COX1 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391886(CHEMBL2147421)
Affinity DataIC50: 1.84E+4nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391886(CHEMBL2147421)
Affinity DataIC50: 1.95E+4nMAssay Description:Inhibition of mPGES1 in IL-1beta treated human A549 cell microsomal membrane assessed as inhibition of PGE2 formation incubated for 15 mins before ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391889(CHEMBL2147419)
Affinity DataIC50: 2.72E+4nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391888(CHEMBL2147418)
Affinity DataIC50: 3.95E+4nMAssay Description:Inhibition of mPGES1 in IL-1beta treated human A549 cell microsomal membrane assessed as inhibition of PGE2 formation incubated for 15 mins before ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391881(CHEMBL2147415)
Affinity DataIC50: 4.14E+4nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391889(CHEMBL2147419)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of mPGES1 in IL-1beta treated human A549 cell microsomal membrane assessed as inhibition of PGE2 formation incubated for 15 mins before ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391881(CHEMBL2147415)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of mPGES1 in IL-1beta treated human A549 cell microsomal membrane assessed as inhibition of PGE2 formation incubated for 15 mins before ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391880(CHEMBL2147423)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391889(CHEMBL2147419)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ram seminal vesicle COX1 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391888(CHEMBL2147418)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ram seminal vesicle COX1 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391885(CHEMBL2147417)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ram seminal vesicle COX1 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391882(CHEMBL2147416)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ram seminal vesicle COX1 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391881(CHEMBL2147415)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ram seminal vesicle COX1 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391882(CHEMBL2147416)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of mPGES1 in IL-1beta treated human A549 cell microsomal membrane assessed as inhibition of PGE2 formation incubated for 15 mins before ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391882(CHEMBL2147416)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391885(CHEMBL2147417)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of sheep placental COX2 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391885(CHEMBL2147417)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391886(CHEMBL2147421)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ram seminal vesicle COX1 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391886(CHEMBL2147421)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of sheep placental COX2 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391889(CHEMBL2147419)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of sheep placental COX2 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391888(CHEMBL2147418)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of sheep placental COX2 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391883(CHEMBL2147424)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391884(CHEMBL463574)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391882(CHEMBL2147416)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of sheep placental COX2 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391883(CHEMBL2147424)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of sheep placental COX2 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391883(CHEMBL2147424)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ram seminal vesicle COX1 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391888(CHEMBL2147418)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391887(CHEMBL2147422)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391885(CHEMBL2147417)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of mPGES1 in IL-1beta treated human A549 cell microsomal membrane assessed as inhibition of PGE2 formation incubated for 15 mins before ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391890(CHEMBL2147420)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391881(CHEMBL2147415)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of sheep placental COX2 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed