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Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50033894
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353432(CHEMBL1829876 | US10196373, Compound 45O)
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353440(CHEMBL1829864 | US10196373, Compound 45F)
Affinity DataIC50: 2.46E+4nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353442(CHEMBL1829871 | US10196373, Compound 45E)
Affinity DataIC50: 2.88E+4nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353439(CHEMBL1829872 | US10196373, Compound 45G)
Affinity DataIC50: 2.88E+4nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353441(CHEMBL1829786)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353445(CHEMBL1829862 | US10196373, Compound 45B)
Affinity DataIC50: 5.19E+4nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353433(CHEMBL1829868 | US10196373, Compound 45N)
Affinity DataIC50: 6.22E+4nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353444(CHEMBL1829870 | US10196373, Compound 45C)
Affinity DataIC50: 6.54E+4nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353435(CHEMBL1829874 | US10196373, Compound 45K)
Affinity DataIC50: 6.72E+4nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353447(CHEMBL1829875 | US10196373, Compound 45M)
Affinity DataIC50: 6.74E+4nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353443(CHEMBL1829863 | US10196373, Compound 45D)
Affinity DataIC50: 7.92E+4nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353436(CHEMBL1829866 | US10196373, Compound 45J)
Affinity DataIC50: 9.03E+4nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353446(CHEMBL1829869 | US10196373, Compound 45A)
Affinity DataIC50: 1.19E+5nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353437(CHEMBL1829873 | US10196373, Compound 45I)
Affinity DataIC50: 1.26E+5nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353438(CHEMBL1829865 | US10196373, Compound 45H)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353434(CHEMBL1829867 | US10196373, Compound 45L)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353444(CHEMBL1829870 | US10196373, Compound 45C)
Affinity DataKi:  6.20E+3nMAssay Description:Inhibition of STAT3 using fluorescent probe 5-carboxyfluorescein-GpYLPQTV-NH2 after 15 mins by fluorescence polarisation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353445(CHEMBL1829862 | US10196373, Compound 45B)
Affinity DataKi:  8.00E+3nMAssay Description:Inhibition of STAT3 using fluorescent probe 5-carboxyfluorescein-GpYLPQTV-NH2 after 15 mins by fluorescence polarisation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353435(CHEMBL1829874 | US10196373, Compound 45K)
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition of STAT3 using fluorescent probe 5-carboxyfluorescein-GpYLPQTV-NH2 after 15 mins by fluorescence polarisation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353432(CHEMBL1829876 | US10196373, Compound 45O)
Affinity DataKi:  1.28E+4nMAssay Description:Inhibition of STAT3 using fluorescent probe 5-carboxyfluorescein-GpYLPQTV-NH2 after 15 mins by fluorescence polarisation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353439(CHEMBL1829872 | US10196373, Compound 45G)
Affinity DataKi:  1.33E+4nMAssay Description:Inhibition of STAT3 using fluorescent probe 5-carboxyfluorescein-GpYLPQTV-NH2 after 15 mins by fluorescence polarisation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353441(CHEMBL1829786)
Affinity DataKi:  1.50E+4nMAssay Description:Inhibition of mouse STAT3 SH2 domain using fluorescent probe 5-carboxyfluorescein-GpYLPQTV-NH2 after 30 mins by fluorescence polarisation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353441(CHEMBL1829786)
Affinity DataKi:  1.55E+4nMAssay Description:Inhibition of STAT3 using fluorescent probe 5-carboxyfluorescein-GpYLPQTV-NH2 after 15 mins by fluorescence polarisation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 1(Mouse)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353441(CHEMBL1829786)
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of mouse STAT1 using fluorescent probe 5-carboxyfluorescein-GpYLPQTV-NH2 after 30 mins by fluorescence polarisation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353442(CHEMBL1829871 | US10196373, Compound 45E)
Affinity DataKi:  2.65E+4nMAssay Description:Inhibition of STAT3 using fluorescent probe 5-carboxyfluorescein-GpYLPQTV-NH2 after 15 mins by fluorescence polarisation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353437(CHEMBL1829873 | US10196373, Compound 45I)
Affinity DataKi:  3.06E+4nMAssay Description:Inhibition of STAT3 using fluorescent probe 5-carboxyfluorescein-GpYLPQTV-NH2 after 15 mins by fluorescence polarisation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353440(CHEMBL1829864 | US10196373, Compound 45F)
Affinity DataKi:  4.10E+4nMAssay Description:Inhibition of STAT3 using fluorescent probe 5-carboxyfluorescein-GpYLPQTV-NH2 after 15 mins by fluorescence polarisation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353438(CHEMBL1829865 | US10196373, Compound 45H)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of STAT3 using fluorescent probe 5-carboxyfluorescein-GpYLPQTV-NH2 after 15 mins by fluorescence polarisation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed