Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 8200
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

LigandChemical structure of BindingDB Monomer ID 236526BDBM236526(2-Ethoxy-10-[(2-N,N-dimethylamino-2-methyl)ethyl]b...)
Affinity DataKi:  11.1nM ΔG°:  -47.2kJ/molepH: 7.4 T: 2°CAssay Description:In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

LigandChemical structure of BindingDB Monomer ID 236524BDBM236524( 2-Methoxy-10-[(2-N,N-dimethylamino-2-methyl)ethyl...)
Affinity DataKi:  11.6nM ΔG°:  -47.1kJ/molepH: 7.4 T: 2°CAssay Description:In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

LigandChemical structure of BindingDB Monomer ID 236533BDBM236533(2-Fluoro-10-(2-N,N-dimethylaminoethyl)isoindolo[2,...)
Affinity DataKi:  24.3nM ΔG°:  -45.2kJ/molepH: 7.4 T: 2°CAssay Description:In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

LigandChemical structure of BindingDB Monomer ID 236521BDBM236521(2-Phenyl-10-(2-N,N-dimethylaminoethyl)benzo[d]isot...)
Affinity DataKi:  26.8nM ΔG°:  -45.0kJ/molepH: 7.4 T: 2°CAssay Description:In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

LigandChemical structure of BindingDB Monomer ID 236525BDBM236525(2-Methoxy-10-[(2-N,N-dimethylamino-2-ethyl)ethyl]b...)
Affinity DataKi:  28.3nM ΔG°:  -44.8kJ/molepH: 7.4 T: 2°CAssay Description:In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

LigandChemical structure of BindingDB Monomer ID 236539BDBM236539(2-Fluoro-7-chloro-10-(2-N,N-dimethylaminoethyl)iso...)
Affinity DataKi:  37.6nM ΔG°:  -44.1kJ/molepH: 7.4 T: 2°CAssay Description:In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

LigandChemical structure of BindingDB Monomer ID 236538BDBM236538(2-Methylthio-10-(2-N,N-dimethylaminoethyl)isoindol...)
Affinity DataKi:  49.7nM ΔG°:  -43.4kJ/molepH: 7.4 T: 2°CAssay Description:In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

LigandChemical structure of BindingDB Monomer ID 236522BDBM236522(2-Bromo-10-[(2-N,N-dimethylamino-2-methyl)ethyl]be...)
Affinity DataKi:  54.1nM ΔG°:  -43.1kJ/molepH: 7.4 T: 2°CAssay Description:In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

LigandChemical structure of BindingDB Monomer ID 236530BDBM236530(2-Isopropoxy-10-[(2-N,N-dimethylamino-2-methyl)eth...)
Affinity DataKi:  73.2nM ΔG°:  -42.4kJ/molepH: 7.4 T: 2°CAssay Description:In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

LigandChemical structure of BindingDB Monomer ID 236534BDBM236534(2-Chloro-10-(2-N,N-dimethylaminoethyl)isoindolo[2,...)
Affinity DataKi:  80.7nM ΔG°:  -42.1kJ/molepH: 7.4 T: 2°CAssay Description:In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

LigandChemical structure of BindingDB Monomer ID 236540BDBM236540(2-Phenyl-10-(2-N,N-dimethylaminoethyl)isoindolo[2,...)
Affinity DataKi:  84.6nM ΔG°:  -42.0kJ/molepH: 7.4 T: 2°CAssay Description:In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

LigandChemical structure of BindingDB Monomer ID 236531BDBM236531(2-Methoxy-10-(2-N,N-dimethylaminoethyl)isoindolo[2...)
Affinity DataKi:  86.7nM ΔG°:  -41.9kJ/molepH: 7.4 T: 2°CAssay Description:In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

LigandChemical structure of BindingDB Monomer ID 236520BDBM236520(10-[(2-N,N-Dimethylamino-2-methyl)ethyl]benzo[d]is...)
Affinity DataKi:  87.6nM ΔG°:  -41.9kJ/molepH: 7.4 T: 2°CAssay Description:In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

LigandChemical structure of BindingDB Monomer ID 236537BDBM236537(10-(2-N,N-dimethylaminoethyl)benzo[d]isoindolo[2,1...)
Affinity DataKi:  92.6nM ΔG°:  -41.8kJ/molepH: 7.4 T: 2°CAssay Description:In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

LigandChemical structure of BindingDB Monomer ID 236523BDBM236523(2-Methoxy-10-(2-N,N-dimethylaminoethyl)benzo[d]iso...)
Affinity DataKi:  96nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

LigandChemical structure of BindingDB Monomer ID 236527BDBM236527(2-Benzyloxy-10-[(2-N,N-dimethylamino-2-methyl)ethy...)
Affinity DataKi:  100nM ΔG°:  -41.6kJ/molepH: 7.4 T: 2°CAssay Description:In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

LigandChemical structure of BindingDB Monomer ID 236535BDBM236535(1-Chloro-10-(2-N,N-dimethylaminoethyl)-4-methyliso...)
Affinity DataKi:  104nM ΔG°:  -41.5kJ/molepH: 7.4 T: 2°CAssay Description:In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

LigandChemical structure of BindingDB Monomer ID 236517BDBM236517(10-[(2-N,N-Dimethylamino-2-methyl)ethyl]-2-fluorob...)
Affinity DataKi:  116nM ΔG°:  -41.2kJ/molepH: 7.4 T: 2°CAssay Description:In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

LigandChemical structure of BindingDB Monomer ID 236519BDBM236519(4-Chloro-10-(2-N,N-dimethylaminoethyl)benzo[d]isot...)
Affinity DataKi:  126nM ΔG°:  -41.0kJ/molepH: 7.4 T: 2°CAssay Description:In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

LigandChemical structure of BindingDB Monomer ID 236543BDBM236543(10-(2-N,N-dimethylaminoethyl)isoindolo[2,1-a]indol...)
Affinity DataKi:  135nM ΔG°:  -40.8kJ/molepH: 7.4 T: 2°CAssay Description:In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

LigandChemical structure of BindingDB Monomer ID 236536BDBM236536(2,4-Difluoro-10-(2-N,N-dimethylaminoethyl)isoindol...)
Affinity DataKi:  153nM ΔG°:  -40.5kJ/molepH: 7.4 T: 2°CAssay Description:In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

LigandChemical structure of BindingDB Monomer ID 236544BDBM236544(2-Methoxy-10-[(2-N,N-dimethylamino-2-methyl)ethyl]...)
Affinity DataKi:  197nM ΔG°:  -39.8kJ/molepH: 7.4 T: 2°CAssay Description:In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

LigandChemical structure of BindingDB Monomer ID 236528BDBM236528(2-Isopropoxy-10-[(2-N,N-dimethylamino-2-methyl)eth...)
Affinity DataKi:  239nM ΔG°:  -39.3kJ/molepH: 7.4 T: 2°CAssay Description:In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

LigandChemical structure of BindingDB Monomer ID 236515BDBM236515(10-(2-N,N-Dimethylaminoethyl)benzo[d]isothiazolo[3...)
Affinity DataKi:  246nM ΔG°:  -39.2kJ/molepH: 7.4 T: 2°CAssay Description:In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

LigandChemical structure of BindingDB Monomer ID 236516BDBM236516(10-(2-N,N-Dimethylaminoethyl)-2-fluorobenzo[d]isot...)
Affinity DataKi:  267nM ΔG°:  -39.0kJ/molepH: 7.4 T: 2°CAssay Description:In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

LigandChemical structure of BindingDB Monomer ID 236518BDBM236518(10-(2-N,N-Dimethylaminoethyl)-2-methyl-8-methoxybe...)
Affinity DataKi:  269nM ΔG°:  -39.0kJ/molepH: 7.4 T: 2°CAssay Description:In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

LigandChemical structure of BindingDB Monomer ID 236532BDBM236532(2-Methoxy-10-[(2-N,N-dimethylamino-2-methyl)ethyl]...)
Affinity DataKi:  279nM ΔG°:  -38.9kJ/molepH: 7.4 T: 2°CAssay Description:In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

LigandChemical structure of BindingDB Monomer ID 236541BDBM236541(10-[(2-N,N-Dimethylamino-2-methyl)ethyl]isoindolo[...)
Affinity DataKi:  296nM ΔG°:  -38.8kJ/molepH: 7.4 T: 2°CAssay Description:In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

LigandChemical structure of BindingDB Monomer ID 236542BDBM236542(2-Chloro-10-(2-N,N-dimethylaminoethyl)isoindolo[2,...)
Affinity DataKi:  393nM ΔG°:  -38.0kJ/molepH: 7.4 T: 2°CAssay Description:In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Suven Life Sciences

LigandChemical structure of BindingDB Monomer ID 236529BDBM236529(2-Cyclohexylmethyloxy-10-[(2-N,N-dimethylamino-2-m...)
Affinity DataKi: >1.00E+3nM ΔG°: >-35.6kJ/molepH: 7.4 T: 2°CAssay Description:In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed