Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50041934
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336144((1R,3S)-4-chloro-N-(3-hydroxycyclohexyl)-5-(4-(tri...)
Affinity DataIC50: 0.501nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418959(CHEMBL1807875)
Affinity DataIC50: 0.631nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418961(CHEMBL1807877)
Affinity DataIC50: 0.631nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418981(CHEMBL1807878)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418965(CHEMBL1807883)
Affinity DataIC50: 3.16nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418964(CHEMBL1807882)
Affinity DataIC50: 3.98nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418960(CHEMBL1807876)
Affinity DataIC50: 5.01nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418963(CHEMBL1807881)
Affinity DataIC50: 12.6nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418979(CHEMBL1807879)
Affinity DataIC50: 12.6nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418973(CHEMBL1807958)
Affinity DataIC50: 19.9nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418984(CHEMBL1807959)
Affinity DataIC50: 39.8nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50336151((1R,3S)-4-chloro-5-(4-fluorophenyl)-N-(3-hydroxycy...)
Affinity DataIC50: 50.1nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418977(CHEMBL1807964)
Affinity DataIC50: 63.1nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418183(CHEMBL1761688)
Affinity DataIC50: 63.1nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418966(CHEMBL1807885)
Affinity DataIC50: 79.4nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418983(CHEMBL1807954)
Affinity DataIC50: 126nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418970(CHEMBL1807955)
Affinity DataIC50: 158nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418974(CHEMBL1807960)
Affinity DataIC50: 158nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418962(CHEMBL1807880)
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418985(CHEMBL1807965)
Affinity DataIC50: 316nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418978(CHEMBL1807966)
Affinity DataIC50: 794nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418982(CHEMBL1807884)
Affinity DataIC50: 794nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418971(CHEMBL1807956)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418976(CHEMBL1807963)
Affinity DataIC50: 1.58E+3nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418967(CHEMBL1807886)
Affinity DataIC50: 1.58E+3nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418968(CHEMBL1807887)
Affinity DataIC50: 1.58E+3nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418980(CHEMBL1807962)
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418969(CHEMBL1807953)
Affinity DataIC50: 3.16E+3nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418975(CHEMBL1807961)
Affinity DataIC50: 5.01E+3nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418972(CHEMBL1807957)
Affinity DataIC50: 5.01E+3nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50418183(CHEMBL1761688)
Affinity DataKi:  6.31E+3nMAssay Description:Displacement of labeled-dofetilide from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed