Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 8198
TargetCarbonic anhydrase 6(Human)
Agri Ibrahim Cecen University

LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  48nM ΔG°:  -41.8kJ/molepH: 7.4 T: 2°CAssay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a period of 3 min ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Agri Ibrahim Cecen University

LigandPNGBDBM50028970(6-Amino-5,6,7,8-tetrahydro-naphthalene-1,2-diol | ...)
Affinity DataKi:  380nM ΔG°:  -36.6kJ/molepH: 7.4 T: 2°CAssay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a period of 3 min ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Agri Ibrahim Cecen University

LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  420nM ΔG°:  -36.4kJ/molepH: 7.4 T: 2°CAssay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a period of 3 min ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Agri Ibrahim Cecen University

LigandPNGBDBM81195(cid_3153 | 6-Amino-5,6,7,8-tetrahydro-naphthalene-...)
Affinity DataKi:  440nM ΔG°:  -36.3kJ/molepH: 7.4 T: 2°CAssay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a period of 3 min ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Agri Ibrahim Cecen University

LigandPNGBDBM236511(CA inhibitor, 6)
Affinity DataKi:  580nM ΔG°:  -35.6kJ/molepH: 7.4 T: 2°CAssay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a period of 3 min ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Agri Ibrahim Cecen University

LigandPNGBDBM236510(CA inhibitor, 5)
Affinity DataKi:  780nM ΔG°:  -34.9kJ/molepH: 7.4 T: 2°CAssay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a period of 3 min ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Agri Ibrahim Cecen University

LigandPNGBDBM50028970(6-Amino-5,6,7,8-tetrahydro-naphthalene-1,2-diol | ...)
Affinity DataKi:  970nM ΔG°:  -34.3kJ/molepH: 7.4 T: 2°CAssay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a period of 3 min ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Agri Ibrahim Cecen University

LigandPNGBDBM81195(cid_3153 | 6-Amino-5,6,7,8-tetrahydro-naphthalene-...)
Affinity DataKi:  1.15E+3nM ΔG°:  -33.9kJ/molepH: 7.4 T: 2°CAssay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a period of 3 min ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Agri Ibrahim Cecen University

LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  3.64E+4nM ΔG°:  -25.3kJ/molepH: 7.4 T: 2°CAssay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a period of 3 min ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 1(Human)
Agri Ibrahim Cecen University

LigandPNGBDBM81195(cid_3153 | 6-Amino-5,6,7,8-tetrahydro-naphthalene-...)
Affinity DataKi:  4.11E+4nM ΔG°:  -25.0kJ/molepH: 7.4 T: 2°CAssay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a period of 3 min ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Agri Ibrahim Cecen University

LigandPNGBDBM50028970(6-Amino-5,6,7,8-tetrahydro-naphthalene-1,2-diol | ...)
Affinity DataKi:  4.51E+4nM ΔG°:  -24.8kJ/molepH: 7.4 T: 2°CAssay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a period of 3 min ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Agri Ibrahim Cecen University

LigandPNGBDBM236511(CA inhibitor, 6)
Affinity DataKi:  1.43E+5nM ΔG°:  -21.9kJ/molepH: 7.4 T: 2°CAssay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a period of 3 min ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Agri Ibrahim Cecen University

LigandPNGBDBM236511(CA inhibitor, 6)
Affinity DataKi:  1.61E+5nM ΔG°:  -21.7kJ/molepH: 7.4 T: 2°CAssay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a period of 3 min ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Agri Ibrahim Cecen University

LigandPNGBDBM236510(CA inhibitor, 5)
Affinity DataKi:  3.63E+5nM ΔG°:  -19.6kJ/molepH: 7.4 T: 2°CAssay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a period of 3 min ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Agri Ibrahim Cecen University

LigandPNGBDBM236510(CA inhibitor, 5)
Affinity DataKi:  4.70E+5nM ΔG°:  -19.0kJ/molepH: 7.4 T: 2°CAssay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a period of 3 min ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed