Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50033602
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348092(CHEMBL1800273)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of SHP2 catalytic domain assessed as inhibition of pNPP to p-nitrophenol conversion after 5 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348092(CHEMBL1800273)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of SHP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348091(GNF-PF-1973 | CHEMBL579363)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348093(CHEMBL1800274)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of SHP2 catalytic domain assessed as inhibition of pNPP to p-nitrophenol conversion after 5 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348091(GNF-PF-1973 | CHEMBL579363)
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of SHP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348092(CHEMBL1800273)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of LMW-PTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 22(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348092(CHEMBL1800273)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of VHXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348092(CHEMBL1800273)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of LARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348092(CHEMBL1800273)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CD45More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348092(CHEMBL1800273)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of TC-PTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348092(CHEMBL1800273)
Affinity DataIC50: 1.18E+5nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348090(CHEMBL1800272)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348094(CHEMBL214303)
Affinity DataIC50: 1.55E+5nMAssay Description:Inhibition of SHP2 catalytic domain assessed as inhibition of pNPP to p-nitrophenol conversion after 5 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348090(CHEMBL1800272)
Affinity DataIC50: 1.60E+5nMAssay Description:Inhibition of SHP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348091(GNF-PF-1973 | CHEMBL579363)
Affinity DataIC50: 1.76E+5nMAssay Description:Inhibition of SHP2 catalytic domain assessed as inhibition of pNPP to p-nitrophenol conversion after 5 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348090(CHEMBL1800272)
Affinity DataIC50: 1.81E+5nMAssay Description:Inhibition of SHP2 catalytic domain assessed as inhibition of pNPP to p-nitrophenol conversion after 5 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348092(CHEMBL1800273)
Affinity DataKi:  4.60E+3nMAssay Description:Competitive inhibition at SHP2 catalytic domain assessed as inhibition of pNPP to p-nitrophenol conversion by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50348092(CHEMBL1800273)
Affinity DataKi:  4.60E+3nMAssay Description:Reversible inhibition at SHP2 catalytic domain assessed as inhibition of pNPP to p-nitrophenol conversion by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed