Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50004542
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483918(CHEMBL1779734)
Affinity DataIC50: 500nMAssay Description:Inhibition of HSP90 in human H1299 cells assessed as degradation of Akt protein after 24 hrs by luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483917(CHEMBL1738738)
Affinity DataIC50: 700nMAssay Description:Inhibition of HSP90 in human H1299 cells assessed as degradation of Akt protein after 24 hrs by luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483920(CHEMBL1738737)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HSP90 in human H1299 cells assessed as degradation of Akt protein after 24 hrs by luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483916(CHEMBL1779589)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of HSP90 in human H1299 cells assessed as degradation of Akt protein after 24 hrs by luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343361(4-(2-methoxyphenyl)-6-methylpyrimidin-2-amine | CH...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HSP90 in human H1299 cells assessed as degradation of Akt protein after 24 hrs by luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483915(CHEMBL1738736)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HSP90 in human H1299 cells assessed as degradation of Akt protein after 24 hrs by luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483919(CHEMBL1779582)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HSP90 in human H1299 cells assessed as degradation of Akt protein after 24 hrs by luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM81730(HSP90 Inhibitor, 4)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of HSP90 in human H1299 cells assessed as degradation of Akt protein after 24 hrs by luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483921(CHEMBL1779583)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of HSP90 in human H1299 cells assessed as degradation of Akt protein after 24 hrs by luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483914(CHEMBL1779580)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of HSP90 in human H1299 cells assessed as degradation of Akt protein after 24 hrs by luminex assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed