Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50033454
TargetAromatase(Human)
Universita` Di Modena E Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM13061(CHEMBL1444 | 4-[(4-cyanophenyl)(1H-1,2,4-triazol-1...)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Universita` Di Modena E Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50345657(rac-3-((1H-imidazol-1-yl)methyl)-1-(3-tert-butyl-4...)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Universita` Di Modena E Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50345645(rac-1-(1H-imidazol-1-yl)-3-phenoxypropan-2-yl 4-me...)
Affinity DataIC50: 16.5nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Universita` Di Modena E Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50345671(rac-1-(2-((1H-imidazol-1-yl)methyl)morpholino)-2-(...)
Affinity DataIC50: 34.5nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Universita` Di Modena E Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50345672(rac-1-(2-((1H-imidazol-1-yl)methyl)morpholino)-2-(...)
Affinity DataIC50: 46.7nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Universita` Di Modena E Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50345648(rac-1-(2-((1H-imidazol-1-yl)methyl)morpholino)-2-(...)
Affinity DataIC50: 59.2nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Universita` Di Modena E Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50345665(N-(3-(1H-imidazol-1-yl)propyl)-4-methoxy-3-methylb...)
Affinity DataIC50: 61.6nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Universita` Di Modena E Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50345666(N-(3-(1H-imidazol-1-yl)propyl)-2,5-dichloro-4-meth...)
Affinity DataIC50: 63.7nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Universita` Di Modena E Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50345660(rac-1-(4-(2-((1H-imidazol-1-yl)methyl)morpholinosu...)
Affinity DataIC50: 66.5nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Universita` Di Modena E Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50345659(rac-2-((1H-imidazol-1-yl)methyl)-4-(4-methoxypheny...)
Affinity DataIC50: 78.8nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Universita` Di Modena E Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50345669(N-(3-(1H-imidazol-1-yl)propyl)-3-fluoro-4-methoxyb...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Universita` Di Modena E Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50345646(N-(3-(1H-imidazol-1-yl)propyl)-2,3-dihydrobenzo[b]...)
Affinity DataIC50: 119nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Universita` Di Modena E Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50345664(N-(3-(1H-imidazol-1-yl)propyl)-2,4,5-trimethylbenz...)
Affinity DataIC50: 172nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Universita` Di Modena E Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50345655(N-(2-(4-fluorophenoxy)phenyl)-2-(1H-imidazol-1-yl)...)
Affinity DataIC50: 248nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Universita` Di Modena E Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50345667(N-(3-(1H-imidazol-1-yl)propyl)-3-tert-butyl-4-meth...)
Affinity DataIC50: 440nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Universita` Di Modena E Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50345644(E/Z-1-(2,4-dichlorophenyl)-3-phenyl-2-(1H-1,2,4-tr...)
Affinity DataIC50: 441nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Universita` Di Modena E Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50345658(5-(8-methoxy-3,4-dihydro-2H-benzo[b][1,4]dioxepin-...)
Affinity DataIC50: 498nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Universita` Di Modena E Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50345673(N-(3-(1H-imidazol-1-yl)propyl)-2,2-dimethyl-3-oxo-...)
Affinity DataIC50: 499nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Universita` Di Modena E Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50345663(N-(3-(1H-imidazol-1-yl)propyl)-4-ethoxynaphthalene...)
Affinity DataIC50: 761nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Universita` Di Modena E Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50345650(rac-N-(1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-3-p...)
Affinity DataIC50: 991nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Universita` Di Modena E Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50345661(N-(3-(1H-imidazol-1-yl)propyl)-4-methyl-3-nitroben...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Universita` Di Modena E Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50345668(N-(3-(1H-imidazol-1-yl)propyl)-4-(N-allylmethylsul...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Universita` Di Modena E Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50345656(rac-2-((1H-1,2,4-triazol-1-yl)methyl)-N-(1-(3-fluo...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Universita` Di Modena E Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50345654(trans-3-(1H-imidazol-1-yl)-N-((4-(5-(pyridin-2-yl)...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Universita` Di Modena E Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50345653(rac-1-(1H-imidazol-1-yl)-3-(4-((2-methylpyrimidin-...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Universita` Di Modena E Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50345649(1'-(2-(1H-1,2,4-triazol-1-yl)acetyl)-7-methoxyspir...)
Affinity DataIC50: 5.79E+3nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Universita` Di Modena E Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50345662(N-(3-(1H-imidazol-1-yl)propyl)-6-methylnicotinamid...)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Universita` Di Modena E Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50345651(rac-N-(2-(1H-1,2,4-triazol-1-yl)propyl)-2-ethyl-3-...)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Universita` Di Modena E Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50345670(N-(2-(4-fluorophenoxy)phenyl)-2-methyl-2-(1H-1,2,4...)
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Universita` Di Modena E Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50345647(rac-7-(2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propoxy)...)
Affinity DataIC50: 2.17E+4nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetAromatase(Human)
Universita` Di Modena E Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50345652(rac-N-(2-(1H-1,2,4-triazol-1-yl)propyl)-2-oxo-2,5,...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed