Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50033426
LigandPNGBDBM31592(PF-2545920 | substituted pyrazole, 9 | US9138494, ...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50334653(5-((1H-benzo[d]imidazol-2-yl)methylthio)-2-methyl-...)
Affinity DataIC50: 12nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345094(2-methyl-5-((1-methyl-1H-benzo[d]imidazol-2-yl)met...)
Affinity DataIC50: 14nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345091(5-(imidazo[1,2-a]pyridin-2-ylmethylthio)-2-methyl-...)
Affinity DataIC50: 15nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50319165(2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrid...)
Affinity DataIC50: 32nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345103(2-(9-bromo-2-methyl-[1,2,4]triazolo[1,5-c]quinazol...)
Affinity DataIC50: 35nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345092(5-(imidazo[1,2-a]pyrimidin-2-ylmethylthio)-2-methy...)
Affinity DataIC50: 55nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM14768((R)-6,7-Dimethoxy-4-[3-(quinoxalin-2-yloxy)-pyrrol...)
Affinity DataIC50: 64nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345086(5-((4-(4-methoxyphenyl)-1-methyl-1H-imidazol-2-yl)...)
Affinity DataIC50: 65nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345093(2-((2-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl...)
Affinity DataIC50: 110nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345089(6-((2-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl...)
Affinity DataIC50: 120nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345102(2-(9-chloro-2-methyl-[1,2,4]triazolo[1,5-c]quinazo...)
Affinity DataIC50: 130nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345087(5-((4-(2-chlorophenyl)-1-methyl-1H-imidazol-2-yl)m...)
Affinity DataIC50: 150nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345090(2-methyl-5-(quinolin-2-ylmethylthio)-[1,2,4]triazo...)
Affinity DataIC50: 160nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345110(2-(2,10-dimethyl-[1,2,4]triazolo[1,5-c]quinazolin-...)
Affinity DataIC50: 170nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345088(2-methyl-5-((1-methyl-4-phenyl-1H-imidazol-2-yl)me...)
Affinity DataIC50: 190nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM14754(CHEMBL19224 | 1-[(3,4-dimethoxyphenyl)methyl]-6,7-...)
Affinity DataIC50: 210nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50345101(2-(9-methoxy-2-methyl-[1,2,4]triazolo[1,5-c]quinaz...)
Affinity DataIC50: 250nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345121(2-(2-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5-ylt...)
Affinity DataIC50: 310nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345112(2-(8-fluoro-2-methyl-[1,2,4]triazolo[1,5-c]quinazo...)
Affinity DataIC50: 320nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345096(2-methyl-5-(pyridin-4-ylmethylthio)-[1,2,4]triazol...)
Affinity DataIC50: 380nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345107(2-(2-methyl-10-(trifluoromethyl)-[1,2,4]triazolo[1...)
Affinity DataIC50: 450nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345113(2-(9-fluoro-2-methyl-[1,2,4]triazolo[1,5-c]quinazo...)
Affinity DataIC50: 460nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345109(2-(2,9-dimethyl-[1,2,4]triazolo[1,5-c]quinazolin-5...)
Affinity DataIC50: 460nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345098(2-(8,9-dimethoxy-2-methyl-[1,2,4]triazolo[1,5-c]qu...)
Affinity DataIC50: 790nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345116(2-(2-((hydroxyimino)methyl)-[1,2,4]triazolo[1,5-c]...)
Affinity DataIC50: 960nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345095(5-((1H-imidazol-2-yl)methylthio)-2-methyl-[1,2,4]t...)
Affinity DataIC50: 990nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345106(2-(10-bromo-2-methyl-[1,2,4]triazolo[1,5-c]quinazo...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345128(5-(2-bromophenyl)-[1,2,4]triazolo[1,5-c]quinazolin...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345108(2-(2,8-dimethyl-[1,2,4]triazolo[1,5-c]quinazolin-5...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345118(2-([1,2,4]triazolo[1,5-c]quinazolin-5-ylthio)aceto...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345122(2-(2-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5-ylt...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345120(2-(2-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5-ylt...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345111(2-(7-fluoro-2-methyl-[1,2,4]triazolo[1,5-c]quinazo...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345114(2-(10-fluoro-2-methyl-[1,2,4]triazolo[1,5-c]quinaz...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345124(2-methyl-5-(methylthio)-[1,2,4]triazolo[1,5-c]quin...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345104(2-(2-methyl-8-(trifluoromethyl)-[1,2,4]triazolo[1,...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345103(2-(9-bromo-2-methyl-[1,2,4]triazolo[1,5-c]quinazol...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of PDE4d6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345105(2-(8-bromo-2-methyl-[1,2,4]triazolo[1,5-c]quinazol...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345123(5-(ethylthio)-2-methyl-[1,2,4]triazolo[1,5-c]quina...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345119(4-(2-(2-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5-...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345126((2-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5-ylsul...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345127(5-(3,4-dimethoxyphenyl)-[1,2,4]triazolo[1,5-c]quin...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50345103(2-(9-bromo-2-methyl-[1,2,4]triazolo[1,5-c]quinazol...)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of PDE5aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345099(2-(2-methyl-9-morpholino-[1,2,4]triazolo[1,5-c]qui...)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345125(2-methyl-[1,2,4]triazolo[1,5-c]quinazoline-5(6H)-t...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345100(2-(2-methyl-9-phenyl-[1,2,4]triazolo[1,5-c]quinazo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345097(1-(3,4-dichlorophenyl)-2-(2-methyl-[1,2,4]triazolo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345117(2-(2-(hydroxymethyl)-[1,2,4]triazolo[1,5-c]quinazo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
LigandPNGBDBM50345115(2-(2-((methoxyimino)methyl)-[1,2,4]triazolo[1,5-c]...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed