Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50033803
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351543(CHEMBL1824696)
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of LPS-induced TLR4 activation in mouse RAW264.7 cells assessed as reduction in NO production after 18 to 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351544(CHEMBL1821757)
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of LPS-induced TLR4 activation in mouse RAW264.7 cells assessed as reduction in NO production after 18 to 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351543(CHEMBL1824696)
Affinity DataIC50: 1.61E+4nMAssay Description:Inhibition of LPS-induced TLR4 activation in mouse RAW264.7 cells assessed as reduction in NO production after 18 to 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351545(CHEMBL1824689)
Affinity DataIC50: 1.65E+4nMAssay Description:Inhibition of LPS-induced TLR4 activation in mouse RAW264.7 cells assessed as reduction in NO production after 18 to 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351546(CHEMBL1824688)
Affinity DataIC50: 1.98E+4nMAssay Description:Inhibition of LPS-induced TLR4 activation in mouse RAW264.7 cells assessed as reduction in NO production after 18 to 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351547(CHEMBL1223751)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as probeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351548(CHEMBL1824697)
Affinity DataIC50: 2.01E+4nMAssay Description:Inhibition of LPS-induced TLR4 activation in mouse RAW264.7 cells assessed as reduction in NO production after 18 to 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351549(CHEMBL1824690)
Affinity DataIC50: 2.18E+4nMAssay Description:Inhibition of LPS-induced TLR4 activation in mouse RAW264.7 cells assessed as reduction in NO production after 18 to 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351550(CHEMBL1824693)
Affinity DataIC50: 2.31E+4nMAssay Description:Inhibition of LPS-induced TLR4 activation in mouse RAW264.7 cells assessed as reduction in NO production after 18 to 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351551(CHEMBL1824698)
Affinity DataIC50: 2.32E+4nMAssay Description:Inhibition of LPS-induced TLR4 activation in mouse RAW264.7 cells assessed as reduction in NO production after 18 to 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351552(CHEMBL1824700)
Affinity DataIC50: 2.37E+4nMAssay Description:Inhibition of LPS-induced TLR4 activation in mouse RAW264.7 cells assessed as reduction in NO production after 18 to 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351553(CHEMBL1824687)
Affinity DataIC50: 2.43E+4nMAssay Description:Inhibition of LPS-induced TLR4 activation in mouse RAW264.7 cells assessed as reduction in NO production after 18 to 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351567(CHEMBL1824691)
Affinity DataIC50: 2.47E+4nMAssay Description:Inhibition of LPS-induced TLR4 activation in mouse RAW264.7 cells assessed as reduction in NO production after 18 to 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351554(CHEMBL1824686)
Affinity DataIC50: 2.48E+4nMAssay Description:Inhibition of LPS-induced TLR4 activation in mouse RAW264.7 cells assessed as reduction in NO production after 18 to 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351555(CHEMBL1824699)
Affinity DataIC50: 2.73E+4nMAssay Description:Inhibition of LPS-induced TLR4 activation in mouse RAW264.7 cells assessed as reduction in NO production after 18 to 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351547(CHEMBL1223751)
Affinity DataIC50: 2.78E+4nMAssay Description:Inhibition of LPS-induced TLR4 activation in mouse RAW264.7 cells assessed as reduction in NO production after 18 to 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351547(CHEMBL1223751)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using bufuralol as probeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351556(CHEMBL1824692)
Affinity DataIC50: 3.21E+4nMAssay Description:Inhibition of LPS-induced TLR4 activation in mouse RAW264.7 cells assessed as reduction in NO production after 18 to 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351547(CHEMBL1223751)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as probeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351557(CHEMBL1824694)
Affinity DataIC50: 4.46E+4nMAssay Description:Inhibition of LPS-induced TLR4 activation in mouse RAW264.7 cells assessed as reduction in NO production after 18 to 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351558(CHEMBL1824682)
Affinity DataIC50: 4.77E+4nMAssay Description:Inhibition of LPS-induced TLR4 activation in mouse RAW264.7 cells assessed as reduction in NO production after 18 to 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351559(CHEMBL1824685)
Affinity DataIC50: 4.77E+4nMAssay Description:Inhibition of LPS-induced TLR4 activation in mouse RAW264.7 cells assessed as reduction in NO production after 18 to 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351560(CHEMBL1824681)
Affinity DataIC50: 5.18E+4nMAssay Description:Inhibition of LPS-induced TLR4 activation in mouse RAW264.7 cells assessed as reduction in NO production after 18 to 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351568(CHEMBL1824701)
Affinity DataIC50: 5.27E+4nMAssay Description:Inhibition of LPS-induced TLR4 activation in mouse RAW264.7 cells assessed as reduction in NO production after 18 to 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351561(CHEMBL1824679)
Affinity DataIC50: 5.73E+4nMAssay Description:Inhibition of LPS-induced TLR4 activation in mouse RAW264.7 cells assessed as reduction in NO production after 18 to 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351562(CHEMBL1824678)
Affinity DataIC50: 6.43E+4nMAssay Description:Inhibition of LPS-induced TLR4 activation in mouse RAW264.7 cells assessed as reduction in NO production after 18 to 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351563(CHEMBL1824684)
Affinity DataIC50: 6.76E+4nMAssay Description:Inhibition of LPS-induced TLR4 activation in mouse RAW264.7 cells assessed as reduction in NO production after 18 to 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351564(CHEMBL1824680)
Affinity DataIC50: 9.25E+4nMAssay Description:Inhibition of LPS-induced TLR4 activation in mouse RAW264.7 cells assessed as reduction in NO production after 18 to 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351565(CHEMBL1824677)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of LPS-induced TLR4 activation in mouse RAW264.7 cells assessed as reduction in NO production after 18 to 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351566(CHEMBL1824683)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of LPS-induced TLR4 activation in mouse RAW264.7 cells assessed as reduction in NO production after 18 to 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351547(CHEMBL1223751)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as probeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetToll-like receptor 4(Human)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351547(CHEMBL1223751)
Affinity DataIC50: 1.11E+5nMAssay Description:Inhibition of LPS-induced TLR4 activation in human whole blood assessed as inhibition of IL-8 release preincubated for 5 to 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetToll-like receptor 4(Human)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351547(CHEMBL1223751)
Affinity DataIC50: 3.16E+5nMAssay Description:Inhibition of LPS-induced TLR4 activation in human whole blood assessed as inhibition of TNFalpha release preincubated for 5 to 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetToll-like receptor 4(Human)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50351547(CHEMBL1223751)
Affinity DataIC50: 3.18E+5nMAssay Description:Inhibition of LPS-induced TLR4 activation in human whole blood assessed as inhibition of IL-6 release preincubated for 5 to 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed