Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50033410
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universidad Nacional De Colombia

Curated by ChEMBL
LigandPNGBDBM50293015(Methyl 4-((4-(2-(6,7-Dimethoxy-1,2,3,4-tetrahydroi...)
Affinity DataIC50: 59nMAssay Description:Inhibition of ABCG2 expressed in human MCF7/Topo cells by Hoechst microplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universidad Nacional De Colombia

Curated by ChEMBL
LigandPNGBDBM50206310(ELACRIDAR HYDROCHLORIDE | N-4-[2-(1,2,3,4-Tetrahyd...)
Affinity DataIC50: 127nMAssay Description:Inhibition of ABCG2 expressed in human MCF7/Topo cells by Hoechst microplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universidad Nacional De Colombia

Curated by ChEMBL
LigandPNGBDBM50344753(N-{4-[2-(6-Methoxy-7-{2-[2-(2-methoxy-ethoxy)-etho...)
Affinity DataIC50: 130nMAssay Description:Inhibition of ABCG2 expressed in human MCF7/Topo cells by Hoechst microplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universidad Nacional De Colombia

Curated by ChEMBL
LigandPNGBDBM50293013(Methyl 4-((4-(2-(6,7-dimethoxy-1,2,3,4-tetrahydroi...)
Affinity DataIC50: 172nMAssay Description:Inhibition of ABCG2 expressed in human MCF7/Topo cells by Hoechst microplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universidad Nacional De Colombia

Curated by ChEMBL
LigandPNGBDBM50344755(N-{4-[2-(7-Methoxy-6-{2-[2-(2-methoxy-ethoxy)-etho...)
Affinity DataIC50: 183nMAssay Description:Inhibition of ABCG2 expressed in human MCF7/Topo cells by Hoechst microplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universidad Nacional De Colombia

Curated by ChEMBL
LigandPNGBDBM50206310(ELACRIDAR HYDROCHLORIDE | N-4-[2-(1,2,3,4-Tetrahyd...)
Affinity DataIC50: 193nMAssay Description:Inhibition of ABCB1 expressed in Kb-V1 cells after 10 mins by calcein-AM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent translocase ABCB1(Human)
Universidad Nacional De Colombia

Curated by ChEMBL
LigandPNGBDBM50075373(CHEMBL348475 | 1N-{4-[2-(6,7-dimethoxy-1,2,3,4-tet...)
Affinity DataIC50: 223nMAssay Description:Inhibition of ABCB1 expressed in Kb-V1 cells after 10 mins by calcein-AM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universidad Nacional De Colombia

Curated by ChEMBL
LigandPNGBDBM50344754(N-{4-[2-(7-Methoxy-6-{2-[2-(2-methoxy-ethoxy)-etho...)
Affinity DataIC50: 390nMAssay Description:Inhibition of ABCG2 expressed in human MCF7/Topo cells by Hoechst microplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universidad Nacional De Colombia

Curated by ChEMBL
LigandPNGBDBM50344752(methyl 4-(4-(2-(6-methoxy-7-(2-(2-(2-methoxyethoxy...)
Affinity DataIC50: 508nMAssay Description:Inhibition of ABCG2 expressed in human MCF7/Topo cells by Hoechst microplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universidad Nacional De Colombia

Curated by ChEMBL
LigandPNGBDBM50075373(CHEMBL348475 | 1N-{4-[2-(6,7-dimethoxy-1,2,3,4-tet...)
Affinity DataIC50: 526nMAssay Description:Inhibition of ABCG2 expressed in human MCF7/Topo cells by Hoechst microplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent translocase ABCB1(Human)
Universidad Nacional De Colombia

Curated by ChEMBL
LigandPNGBDBM50344760(N-{4-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ABCB1 expressed in Kb-V1 cells after 10 mins by calcein-AM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universidad Nacional De Colombia

Curated by ChEMBL
LigandPNGBDBM50344761(N-{4-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of ABCG2 expressed in human MCF7/Topo cells by Hoechst microplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universidad Nacional De Colombia

Curated by ChEMBL
LigandPNGBDBM50344757(N-{4-[2-(6-Methoxy-7-{2-[2-(2-methoxy-ethoxy)-etho...)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of ABCG2 expressed in human MCF7/Topo cells by Hoechst microplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universidad Nacional De Colombia

Curated by ChEMBL
LigandPNGBDBM50293013(Methyl 4-((4-(2-(6,7-dimethoxy-1,2,3,4-tetrahydroi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ABCB1 expressed in Kb-V1 cells after 10 mins by calcein-AM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universidad Nacional De Colombia

Curated by ChEMBL
LigandPNGBDBM50293015(Methyl 4-((4-(2-(6,7-Dimethoxy-1,2,3,4-tetrahydroi...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of ABCB1 expressed in Kb-V1 cells after 10 mins by calcein-AM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universidad Nacional De Colombia

Curated by ChEMBL
LigandPNGBDBM50344761(N-{4-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ABCB1 expressed in Kb-V1 cells after 10 mins by calcein-AM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universidad Nacional De Colombia

Curated by ChEMBL
LigandPNGBDBM50344752(methyl 4-(4-(2-(6-methoxy-7-(2-(2-(2-methoxyethoxy...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ABCB1 expressed in Kb-V1 cells after 10 mins by calcein-AM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universidad Nacional De Colombia

Curated by ChEMBL
LigandPNGBDBM50344753(N-{4-[2-(6-Methoxy-7-{2-[2-(2-methoxy-ethoxy)-etho...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ABCB1 expressed in Kb-V1 cells after 10 mins by calcein-AM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universidad Nacional De Colombia

Curated by ChEMBL
LigandPNGBDBM50344759(N-{4-[2-(7-Methoxy-6-{2-[2-(2-methoxy-ethoxy)-etho...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ABCG2 expressed in human MCF7/Topo cells by Hoechst microplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universidad Nacional De Colombia

Curated by ChEMBL
LigandPNGBDBM50344758(N-{4-[2-(7-Methoxy-6-{2-[2-(2-methoxy-ethoxy)-etho...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ABCG2 expressed in human MCF7/Topo cells by Hoechst microplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universidad Nacional De Colombia

Curated by ChEMBL
LigandPNGBDBM50344756(N-{4-[2-(6-Methoxy-7-{2-[2-(2-methoxy-ethoxy)-etho...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ABCG2 expressed in human MCF7/Topo cells by Hoechst microplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universidad Nacional De Colombia

Curated by ChEMBL
LigandPNGBDBM50344755(N-{4-[2-(7-Methoxy-6-{2-[2-(2-methoxy-ethoxy)-etho...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ABCB1 expressed in Kb-V1 cells after 10 mins by calcein-AM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universidad Nacional De Colombia

Curated by ChEMBL
LigandPNGBDBM50344756(N-{4-[2-(6-Methoxy-7-{2-[2-(2-methoxy-ethoxy)-etho...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ABCB1 expressed in Kb-V1 cells after 10 mins by calcein-AM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universidad Nacional De Colombia

Curated by ChEMBL
LigandPNGBDBM50344758(N-{4-[2-(7-Methoxy-6-{2-[2-(2-methoxy-ethoxy)-etho...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ABCB1 expressed in Kb-V1 cells after 10 mins by calcein-AM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universidad Nacional De Colombia

Curated by ChEMBL
LigandPNGBDBM50344754(N-{4-[2-(7-Methoxy-6-{2-[2-(2-methoxy-ethoxy)-etho...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ABCB1 expressed in Kb-V1 cells after 10 mins by calcein-AM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universidad Nacional De Colombia

Curated by ChEMBL
LigandPNGBDBM50344760(N-{4-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ABCG2 expressed in human MCF7/Topo cells by Hoechst microplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universidad Nacional De Colombia

Curated by ChEMBL
LigandPNGBDBM50344757(N-{4-[2-(6-Methoxy-7-{2-[2-(2-methoxy-ethoxy)-etho...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ABCB1 expressed in Kb-V1 cells after 10 mins by calcein-AM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universidad Nacional De Colombia

Curated by ChEMBL
LigandPNGBDBM50344759(N-{4-[2-(7-Methoxy-6-{2-[2-(2-methoxy-ethoxy)-etho...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ABCB1 expressed in Kb-V1 cells after 10 mins by calcein-AM assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed