Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50033403
TargetD(1A) dopamine receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50170660(CHEMBL521582 | [2-(4-Methoxy-3-phenethyloxy-phenyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]SCH233930 from human D1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50170660(CHEMBL521582 | [2-(4-Methoxy-3-phenethyloxy-phenyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(2) dopamine receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50170660(CHEMBL521582 | [2-(4-Methoxy-3-phenethyloxy-phenyl...)
Affinity DataKi:  1.03nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(4) dopamine receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]N-methylspiperone from human D4 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50344628(N-(2-(2-methoxy-5-methylbenzamido)ethyl)-4-azahexa...)
Affinity DataKi:  7.60nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50344629(N-(2-(4-methoxy-3-phenethoxyphenyl)ethyl)-4-azahex...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]SCH233930 from human D1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50344630(N-(4-(4-Fluoro)butyrophenone)-4-azahexacyclo[5.4.1...)
Affinity DataKi:  27nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  48nMAssay Description:Displacement of [3H]SCH233930 from human D5 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50344630(N-(4-(4-Fluoro)butyrophenone)-4-azahexacyclo[5.4.1...)
Affinity DataKi:  93nMAssay Description:Displacement of [3H]N-methylspiperone from human D4 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50344630(N-(4-(4-Fluoro)butyrophenone)-4-azahexacyclo[5.4.1...)
Affinity DataKi:  209nMAssay Description:Displacement of [3H]SCH233930 from human D1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50344630(N-(4-(4-Fluoro)butyrophenone)-4-azahexacyclo[5.4.1...)
Affinity DataKi:  1.72E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50344630(N-(4-(4-Fluoro)butyrophenone)-4-azahexacyclo[5.4.1...)
Affinity DataKi:  1.96E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50344630(N-(4-(4-Fluoro)butyrophenone)-4-azahexacyclo[5.4.1...)
Affinity DataKi:  2.37E+3nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50137617(N-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-y...)
Affinity DataKi:  2.85E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50137617(N-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-y...)
Affinity DataKi:  3.76E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50344628(N-(2-(2-methoxy-5-methylbenzamido)ethyl)-4-azahexa...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50344629(N-(2-(4-methoxy-3-phenethoxyphenyl)ethyl)-4-azahex...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50344628(N-(2-(2-methoxy-5-methylbenzamido)ethyl)-4-azahexa...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50344630(N-(4-(4-Fluoro)butyrophenone)-4-azahexacyclo[5.4.1...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH233930 from human D5 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50344629(N-(2-(4-methoxy-3-phenethoxyphenyl)ethyl)-4-azahex...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH233930 from human D1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50137617(N-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-y...)
Affinity DataKi:  1.04E+4nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed