Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50033309
TargetBeta-secretase 1(Human)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50242015(CHEMBL518543 | Kuwanon C, 4 | kuwanon C)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human recombinant BACE-1 expressed in HEK293 cells assessed as inhibition of amyloid precursor protein cleavage into amyloid beta after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50343136(Kuwanon A | CHEMBL1770312)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human recombinant BACE-1 expressed in HEK293 cells assessed as inhibition of amyloid precursor protein cleavage into amyloid beta after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-...)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of human recombinant BACE-1 expressed in HEK293 cells assessed as inhibition of amyloid precursor protein cleavage into amyloid beta after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50242014(Morusin, 3 | cid_5281671 | Morusin | CHEMBL464006 ...)
Affinity DataIC50: 5.94E+4nMAssay Description:Inhibition of human recombinant BACE-1 expressed in HEK293 cells assessed as inhibition of amyloid precursor protein cleavage into amyloid beta after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50269559(Norartocarpetin, 5 | CHEMBL463145 | 2-(2,4-dihydro...)
Affinity DataIC50: 6.06E+4nMAssay Description:Inhibition of human recombinant BACE-1 expressed in HEK293 cells assessed as inhibition of amyloid precursor protein cleavage into amyloid beta after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50343137(Cycolmorusin, 2 | CHEMBL1770313 | Cyclomorusin)
Affinity DataIC50: 1.01E+5nMAssay Description:Inhibition of human recombinant BACE-1 expressed in HEK293 cells assessed as inhibition of amyloid precursor protein cleavage into amyloid beta after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50343139(Mormin | CHEMBL1770315)
Affinity DataIC50: 1.04E+5nMAssay Description:Inhibition of human recombinant BACE-1 expressed in HEK293 cells assessed as inhibition of amyloid precursor protein cleavage into amyloid beta after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50343138(Morusinol | CHEMBL1719948)
Affinity DataIC50: 1.36E+5nMAssay Description:Inhibition of human recombinant BACE-1 expressed in HEK293 cells assessed as inhibition of amyloid precursor protein cleavage into amyloid beta after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50343140(Neocyclomorusin | CHEMBL1770314)
Affinity DataIC50: 1.46E+5nMAssay Description:Inhibition of human recombinant BACE-1 expressed in HEK293 cells assessed as inhibition of amyloid precursor protein cleavage into amyloid beta after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50242015(CHEMBL518543 | Kuwanon C, 4 | kuwanon C)
Affinity DataKi:  2.20E+3nMAssay Description:Noncompetitive inhibition of human recombinant BACE-1 by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50343136(Kuwanon A | CHEMBL1770312)
Affinity DataKi:  1.06E+4nMAssay Description:Noncompetitive inhibition of human recombinant BACE-1 by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50242014(Morusin, 3 | cid_5281671 | Morusin | CHEMBL464006 ...)
Affinity DataKi:  6.41E+4nMAssay Description:Noncompetitive inhibition of human recombinant BACE-1 by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50269559(Norartocarpetin, 5 | CHEMBL463145 | 2-(2,4-dihydro...)
Affinity DataKi:  8.26E+4nMAssay Description:Noncompetitive inhibition of human recombinant BACE-1 by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed