Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50033305
TargetCalpain-1 catalytic subunit(Human)
College of Pharmacy Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50167706(3-Methyl-4-oxo-4H-chromene-2-carboxylic acid ((S)-...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
College of Pharmacy Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50343071((S)-2-(3,4-dihydroxybenzylidene)-N-(4-(4-methoxyph...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
College of Pharmacy Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50343074((S)-N-(4-(benzylamino)-3,4-dioxo-1-phenylbutan-2-y...)
Affinity DataIC50: 320nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
College of Pharmacy Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50343070((S)-N-(4-(benzylamino)-3,4-dioxo-1-phenylbutan-2-y...)
Affinity DataIC50: 360nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
College of Pharmacy Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50343069((S)-3-(2-(3,4-dihydroxybenzylidene)butanamido)-N-(...)
Affinity DataIC50: 460nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
College of Pharmacy Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50343073((S)-2-(3,4-dihydroxybenzylidene)-N-(4-(4-methoxyph...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
College of Pharmacy Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50265975((S)-N-(4-amino-3,4-dioxo-1-phenylbutan-2-yl)-4-(2,...)
Affinity DataIC50: 520nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
College of Pharmacy Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50343068((S)-N-benzyl-3-(2-(3,4-dihydroxybenzylidene)butana...)
Affinity DataIC50: 610nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
College of Pharmacy Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50343075((S)-2-(4-hydroxy-3-methoxybenzylidene)-N-(4-(4-met...)
Affinity DataIC50: 630nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
College of Pharmacy Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50343072((S)-N-(4-(benzylamino)-3,4-dioxo-1-phenylbutan-2-y...)
Affinity DataIC50: 670nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
College of Pharmacy Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50343076((S)-2-(3,4-dimethoxybenzylidene)-N-(4-(4-methoxyph...)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
College of Pharmacy Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50343067((S)-N-benzyl-3-(3-(3,4-dihydroxyphenyl)acrylamido)...)
Affinity DataIC50: 6.07E+3nMAssay Description:Inhibition of human erythrocytes mu-calpain using Suc-Leu-Tyr-AMC fluorogenic substrate after 30 mins by spectrofluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed