Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50033348
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50149806(2''-Amino-6''-(2-hydroxy-phenyl)-1,2,3,4,5,6-hexah...)
Affinity DataIC50: 150nMAssay Description:Inhibition of IKK2 using 5-FAM-GRHDSGLDSMK-NH2 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343673(4-(4-(4-(morpholinosulfonyl)phenyl)pyrimidin-2-yla...)
Affinity DataIC50: 210nMAssay Description:Inhibition of p38betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343673(4-(4-(4-(morpholinosulfonyl)phenyl)pyrimidin-2-yla...)
Affinity DataIC50: 480nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343673(4-(4-(4-(morpholinosulfonyl)phenyl)pyrimidin-2-yla...)
Affinity DataIC50: 880nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343673(4-(4-(4-(morpholinosulfonyl)phenyl)pyrimidin-2-yla...)
Affinity DataIC50: 920nMAssay Description:Inhibition of IKK2 using 5-FAM-GRHDSGLDSMK-NH2 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343674(4-(4-(piperazin-1-ylsulfonyl)phenyl)-N-(piperidin-...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of IKK2 using 5-FAM-GRHDSGLDSMK-NH2 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343673(4-(4-(4-(morpholinosulfonyl)phenyl)pyrimidin-2-yla...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343671(4-(4-(morpholinosulfonyl)phenyl)-N-(piperidin-4-yl...)
Affinity DataIC50: 2.09E+3nMAssay Description:Inhibition of IKK2 using 5-FAM-GRHDSGLDSMK-NH2 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343672(N-(1-(methylsulfonyl)piperidin-4-yl)-4-(4-(morphol...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of IKK2 using 5-FAM-GRHDSGLDSMK-NH2 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343678(N-(1-(methylsulfonyl)piperidin-4-yl)-4-(4-(piperaz...)
Affinity DataIC50: 3.14E+3nMAssay Description:Inhibition of IKK2 using 5-FAM-GRHDSGLDSMK-NH2 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343667(4-(4-chlorophenyl)-N-(piperidin-4-yl)pyrimidin-2-a...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of IKK2 using 5-FAM-GRHDSGLDSMK-NH2 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343668(4-(4-chlorophenyl)-N-(1-(methylsulfonyl)piperidin-...)
Affinity DataIC50: 3.67E+3nMAssay Description:Inhibition of IKK2 using 5-FAM-GRHDSGLDSMK-NH2 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343669(4-(4-(4-chlorophenyl)pyrimidin-2-ylamino)piperidin...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of IKK2 using 5-FAM-GRHDSGLDSMK-NH2 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343679(4-(4-(4-(piperazin-1-ylsulfonyl)phenyl)pyrimidin-2...)
Affinity DataIC50: 3.85E+3nMAssay Description:Inhibition of IKK2 using 5-FAM-GRHDSGLDSMK-NH2 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343677(4-(4-(4-(4-methylpiperazin-1-ylsulfonyl)phenyl)pyr...)
Affinity DataIC50: 4.25E+3nMAssay Description:Inhibition of IKK2 using 5-FAM-GRHDSGLDSMK-NH2 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343673(4-(4-(4-(morpholinosulfonyl)phenyl)pyrimidin-2-yla...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343675(N-(1-methylpiperidin-4-yl)-4-(4-(morpholinosulfony...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of IKK2 using 5-FAM-GRHDSGLDSMK-NH2 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343676(4-(4-(4-methylpiperazin-1-ylsulfonyl)phenyl)-N-(pi...)
Affinity DataIC50: 7.02E+3nMAssay Description:Inhibition of IKK2 using 5-FAM-GRHDSGLDSMK-NH2 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343670(4-(4-chlorophenyl)-N-(1-methylpiperidin-4-yl)pyrim...)
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibition of IKK2 using 5-FAM-GRHDSGLDSMK-NH2 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343674(4-(4-(piperazin-1-ylsulfonyl)phenyl)-N-(piperidin-...)
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343673(4-(4-(4-(morpholinosulfonyl)phenyl)pyrimidin-2-yla...)
Affinity DataIC50: 2.04E+4nMAssay Description:Inhibition of IKK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343674(4-(4-(piperazin-1-ylsulfonyl)phenyl)-N-(piperidin-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343674(4-(4-(piperazin-1-ylsulfonyl)phenyl)-N-(piperidin-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343674(4-(4-(piperazin-1-ylsulfonyl)phenyl)-N-(piperidin-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343674(4-(4-(piperazin-1-ylsulfonyl)phenyl)-N-(piperidin-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of p38betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343674(4-(4-(piperazin-1-ylsulfonyl)phenyl)-N-(piperidin-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of IKK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed