Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50033263
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM6471(4-[(2,4-dichloro-5-methoxyphenyl)amino]-7-methoxy-...)
Affinity DataIC50: 0.460nMAssay Description:Inhibition of c-SRCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM8(trans-1,2-cyclohexanediol | (1R)-cyclohexane-1,2-d...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of c-SRCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 1nMAssay Description:Inhibition of c-SRCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM12255(CHEMBL217092 | N-(5-chloro-2H-1,3-benzodioxol-4-yl...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of c-SRCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50303801(N-benzyl-2-(5-(4-(2-morpholinoethoxy)phenyl)pyridi...)
Affinity DataIC50: 20nMAssay Description:Inhibition of c-SRCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342390(3-Amino-6-(2-dimethylamino-ethylamino)-4-phenylthi...)
Affinity DataIC50: 32nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342392(3-Amino-4-benzyl-6-(2-dimethylamino-ethylamino)-th...)
Affinity DataIC50: 40nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342393(3-Amino-6-(2-dimethylamino-ethylamino)-4-propylthi...)
Affinity DataIC50: 63nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342391(3-Amino-6-(2-dimethylamino-ethylamino)-4-phenylthi...)
Affinity DataIC50: 68nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342389(3-Amino-6-(2-dimethylamino-ethylamino)-4-phenylthi...)
Affinity DataIC50: 107nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342387(3-Amino-6-(2-dimethylamino-ethylamino)-4-methylthi...)
Affinity DataIC50: 230nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342388(3-Amino-6-(2-dimethylamino-ethylamino)-4-methylthi...)
Affinity DataIC50: 246nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342379(3-Amino-4,6-dimethyl-thieno[2,3-b]pyridine-2-carbo...)
Affinity DataIC50: 269nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342386(3-Amino-4-methyl-6-trifluoromethyl-thieno[2,3-b]py...)
Affinity DataIC50: 330nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342381(3-Amino-4,6-dimethyl-thieno[2,3-b]pyridine-2-carbo...)
Affinity DataIC50: 769nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342384(3-Amino-4,6-dimethyl-thieno[2,3-b]pyridine-2-carbo...)
Affinity DataIC50: 840nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342382(3-Amino-thieno[2,3-b]pyridine-2-carboxylic acid(3-...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342385(3-Amino-4-methyl-6-trifluoromethyl-thieno[2,3-b]py...)
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342395(3-Amino-6-(2-dimethylamino-ethylamino)-5-propylthi...)
Affinity DataIC50: 2.08E+3nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342394(3-Amino-5-benzyl-6-(2-dimethylamino-ethylamino)-th...)
Affinity DataIC50: 3.87E+3nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342383(3-Amino-4,6-dimethyl-thieno[2,3-b]pyridine-2-carbo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342380(3-Amino-thieno[2,3-b]pyridine-2-carboxylic acid na...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed