Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50039410
TargetSubstance-P receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50418331(SPERGUALIN)
Affinity DataIC50: 0.0794nMAssay Description:Binding affinity to human NK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50001450(Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met NH2 | ...)
Affinity DataIC50: 1.5nMAssay Description:Displacement of [125I]BH-SP from human recombinant NK1 receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50342013(N-[3,5-Bis(trifluoromethyl)benzyl]-N,2-dimethyl-6-...)
Affinity DataIC50: 4.80nMAssay Description:Displacement of [125I]BH-SP from human recombinant NK1 receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50418331(SPERGUALIN)
Affinity DataIC50: 12.6nMAssay Description:Binding affinity to gerbil NK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50140776(2-Methyl-4-phenyl-quinoline-3-carboxylic acid (3,5...)
Affinity DataIC50: 19nMAssay Description:Displacement of [125I]BH-SP from human recombinant NK1 receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50342018(N-[3,5-Bis(trifluoromethyl)benzyl]-N,2-dimethyl-4-...)
Affinity DataIC50: 32nMAssay Description:Displacement of [125I]BH-SP from human recombinant NK1 receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50342011(N-[3,5-Bis(trifluoromethyl)benzyl]-4-phenyl-N,2,6-...)
Affinity DataIC50: 41nMAssay Description:Displacement of [125I]BH-SP from human recombinant NK1 receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50140782(2-Hydroxymethyl-4-phenyl-quinoline-3-carboxylic ac...)
Affinity DataIC50: 42nMAssay Description:Displacement of [125I]BH-SP from human recombinant NK1 receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50342015(N-[3,5-Bis(trifluoromethyl)benzyl]-2-(chloromethyl...)
Affinity DataIC50: 52nMAssay Description:Displacement of [125I]BH-SP from human recombinant NK1 receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50342014(N-[3,5-Bis(trifluoromethyl)benzyl]-2-methyl-6-(4-m...)
Affinity DataIC50: 53nMAssay Description:Displacement of [125I]BH-SP from human recombinant NK1 receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50342023(N-[3,5-Bis(trifluoromethyl)benzyl]-N,5-dimethyl-7-...)
Affinity DataIC50: 53nMAssay Description:Displacement of [125I]BH-SP from human recombinant NK1 receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50342025(N-[3,5-Bis(trifluoromethyl)benzyl]-N,5-dimethyl-7-...)
Affinity DataIC50: 57nMAssay Description:Displacement of [125I]BH-SP from human recombinant NK1 receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50342017(N-[3,5-Bis(trifluoromethyl)benzyl]-6-chloro-N,2-di...)
Affinity DataIC50: 91nMAssay Description:Displacement of [125I]BH-SP from human recombinant NK1 receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50140786(4-Phenyl-quinoline-3-carboxylic acid (3,5-bis-trif...)
Affinity DataIC50: 92nMAssay Description:Displacement of [125I]BH-SP from human recombinant NK1 receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50342021(N-[3,5-Bis(trifluoromethyl)benzyl]-N,2-dimethyl-4-...)
Affinity DataIC50: 98nMAssay Description:Displacement of [125I]BH-SP from human recombinant NK1 receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50140775(4-Phenyl-quinoline-3-carboxylic acid 3,5-bis-trifl...)
Affinity DataIC50: 208nMAssay Description:Displacement of [125I]BH-SP from human recombinant NK1 receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50140783(2-Hydroxymethyl-4-phenyl-quinoline-3-carboxylic ac...)
Affinity DataIC50: 227nMAssay Description:Displacement of [125I]BH-SP from human recombinant NK1 receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50342016(N-[3,5-Bis(trifluoromethyl)benzyl]-2-(chloromethyl...)
Affinity DataIC50: 235nMAssay Description:Displacement of [125I]BH-SP from human recombinant NK1 receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50140772(2-Methyl-4-phenyl-quinoline-3-carboxylic acid 3,5-...)
Affinity DataIC50: 257nMAssay Description:Displacement of [125I]BH-SP from human recombinant NK1 receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50342019(N-[3,5-Bis(trifluoromethyl)benzyl]-6-chloro-2-meth...)
Affinity DataIC50: 270nMAssay Description:Displacement of [125I]BH-SP from human recombinant NK1 receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50342026(N-[3,5-Bis(trifluoromethyl)benzyl]-5-methyl-7-phen...)
Affinity DataIC50: 279nMAssay Description:Displacement of [125I]BH-SP from human recombinant NK1 receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50342020(N-[3,5-Bis(trifluoromethyl)benzyl]-2-methyl-4-phen...)
Affinity DataIC50: 342nMAssay Description:Displacement of [125I]BH-SP from human recombinant NK1 receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50342012(N-[3,5-Bis(trifluoromethyl)benzyl]-2,6-dimethyl-4-...)
Affinity DataIC50: 434nMAssay Description:Displacement of [125I]BH-SP from human recombinant NK1 receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50342022(N-[3,5-Bis(trifluoromethyl)benzyl]-2-methyl-4-phen...)
Affinity DataIC50: 653nMAssay Description:Displacement of [125I]BH-SP from human recombinant NK1 receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50342024(N-[3,5-Bis(trifluoromethyl)benzyl]-5-methyl-7-phen...)
Affinity DataIC50: 698nMAssay Description:Displacement of [125I]BH-SP from human recombinant NK1 receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed