Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50033240
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM12576(JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...)
Affinity DataIC50: 27nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341918((2-heptylamino-1-phosphono-ethyl)-phosphonic acid ...)
Affinity DataIC50: 58nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341912(1-[(n-Dec-1-ylamino)ethyl]1,1-bisphosphonic acid |...)
Affinity DataIC50: 68nMAssay Description:Inhibition of Toxoplasma gondii FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM12576(JMC515594 Compound 64 | Risdronate | CHEMBL923 | R...)
Affinity DataIC50: 74nMAssay Description:Inhibition of Toxoplasma gondii FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341914(1-[(n-Dodec-1-ylamino)ethyl]1,1-bisphosphonic acid...)
Affinity DataIC50: 93nMAssay Description:Inhibition of Toxoplasma gondii FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341917(1-[(n-hex-1-ylamino)ethyl]-1,1-bisphosphonic acid ...)
Affinity DataIC50: 140nMAssay Description:Inhibition of Toxoplasma gondii FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetSolanesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341916(1-[(n-oct-1-ylamino)ethyl]-1,1-bisphosphonic acid ...)
Affinity DataIC50: 272nMAssay Description:Inhibition of Trypanosoma cruzi SPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341915(1-[(n-Tetradec-1-ylamino)ethyl]1,1-bisphosphonic a...)
Affinity DataIC50: 292nMAssay Description:Inhibition of Toxoplasma gondii FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341911(1-[(n-Non-1-ylamino)ethyl]1,1-bisphosphonic acid |...)
Affinity DataIC50: 430nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341911(1-[(n-Non-1-ylamino)ethyl]1,1-bisphosphonic acid |...)
Affinity DataIC50: 440nMAssay Description:Inhibition of Toxoplasma gondii FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341917(1-[(n-hex-1-ylamino)ethyl]-1,1-bisphosphonic acid ...)
Affinity DataIC50: 490nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341914(1-[(n-Dodec-1-ylamino)ethyl]1,1-bisphosphonic acid...)
Affinity DataIC50: 811nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341913(1-[(n-Undec-1-ylamino)ethyl]1,1-bisphosphonic acid...)
Affinity DataIC50: 856nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341913(1-[(n-Undec-1-ylamino)ethyl]1,1-bisphosphonic acid...)
Affinity DataIC50: 868nMAssay Description:Inhibition of Toxoplasma gondii FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341915(1-[(n-Tetradec-1-ylamino)ethyl]1,1-bisphosphonic a...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341912(1-[(n-Dec-1-ylamino)ethyl]1,1-bisphosphonic acid |...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341910(1-[(Benzylamino)ethyl]1,1-bisphosphonic acid | CHE...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341916(1-[(n-oct-1-ylamino)ethyl]-1,1-bisphosphonic acid ...)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetSolanesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341917(1-[(n-hex-1-ylamino)ethyl]-1,1-bisphosphonic acid ...)
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of Trypanosoma cruzi SPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetSolanesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341913(1-[(n-Undec-1-ylamino)ethyl]1,1-bisphosphonic acid...)
Affinity DataIC50: 3.08E+3nMAssay Description:Inhibition of Trypanosoma cruzi SPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetSolanesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341914(1-[(n-Dodec-1-ylamino)ethyl]1,1-bisphosphonic acid...)
Affinity DataIC50: 3.18E+3nMAssay Description:Inhibition of Trypanosoma cruzi SPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetSolanesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341910(1-[(Benzylamino)ethyl]1,1-bisphosphonic acid | CHE...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi SPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetSolanesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341912(1-[(n-Dec-1-ylamino)ethyl]1,1-bisphosphonic acid |...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi SPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed