Compile Data Set for Download or QSAR
Report error Found 63 Enz. Inhib. hit(s) with all data for entry = 50033231
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341773(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataEC50:  378nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341759(2-Methyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataEC50: >2.50E+4nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341760(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataEC50:  660nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using [14C]palmitic acid by TLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM27947(2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)
Affinity DataEC50:  1.44E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341783(4-(4-{4-[(2-Phenyl-5-trifluoromethyloxazole-4-carb...)
Affinity DataEC50:  220nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341782(4-(4-{4-[(2-Phenyl-5-trifluoromethyloxazole-4-carb...)
Affinity DataEC50:  493nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341781(4-(4-{4-[(2-Phenyl-5-trifluoromethyloxazole-4-carb...)
Affinity DataEC50:  365nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341780(4-{5-[(2-Phenyl-5-trifluoromethyloxazole-4-carbony...)
Affinity DataEC50:  2.36E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341779(4-(4-{4-[(2-Phenyl-5-trifluoromethyloxazole-4-carb...)
Affinity DataEC50:  1.07E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341778(4-(4-{5-[(2-Phenyl-5-trifluoromethyloxazole-4-carb...)
Affinity DataEC50:  1.76E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341777(4-{4-[(2-Phenyl-5-trifluoromethyloxazole-4-carbony...)
Affinity DataEC50:  371nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341776(N-(4-(1-(cyclopropanecarbonyl)piperidin-4-yl)pheny...)
Affinity DataEC50:  362nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341775(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataEC50:  165nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341774(4-{4-[(2-Phenyl-5-trifluoromethyloxazole-4-carbony...)
Affinity DataEC50:  190nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341772(5-[(2-Phenyl-5-trifluoromethyloxazole-4-carbonyl)a...)
Affinity DataEC50:  219nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341771(4-{5-[(2-Phenyl-5-trifluoromethyloxazole-4-carbony...)
Affinity DataEC50:  410nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341770(4-{5-[(2-Phenyl-5-trifluoromethyloxazole-4-carbony...)
Affinity DataEC50:  93nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341769(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataEC50:  138nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341768(4-{5-[(2-Phenyl-5-trifluoromethyloxazole-4-carbony...)
Affinity DataEC50:  216nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341767((1-{5-[(2-Phenyl-5-trifluoromethyloxazole-4-carbon...)
Affinity DataEC50: >2.50E+4nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341766(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataEC50:  2.50E+4nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341765((S)-2-Phenyl-5-trifluoromethyloxazole-4-carboxylic...)
Affinity DataEC50:  5.66E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341764(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataEC50:  228nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341763(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataEC50:  534nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341762(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataEC50:  1.80E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341761(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataEC50: >2.50E+4nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341760(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataEC50:  661nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341785((1R,2R)-2-(3'-fluoro-4'-(3-phenylureido)biphenylca...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341766(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341768(4-{5-[(2-Phenyl-5-trifluoromethyloxazole-4-carbony...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341778(4-(4-{5-[(2-Phenyl-5-trifluoromethyloxazole-4-carb...)
Affinity DataIC50: 35nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341760(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataIC50: 38nMAssay Description:Inhibition of human DGAT1 using [14C]palmitic acid by TLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341760(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataIC50: 38nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341770(4-{5-[(2-Phenyl-5-trifluoromethyloxazole-4-carbony...)
Affinity DataIC50: 41nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341784(N-(2-(2-phenyl-5-(trifluoromethyl)-1H-imidazole-4-...)
Affinity DataIC50: 44nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected Sf9 cells using [14C]oleoyl-CoA after 15 mins by TLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341763(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataIC50: 48nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341782(4-(4-{4-[(2-Phenyl-5-trifluoromethyloxazole-4-carb...)
Affinity DataIC50: 57nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341769(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataIC50: 59nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341776(N-(4-(1-(cyclopropanecarbonyl)piperidin-4-yl)pheny...)
Affinity DataIC50: 67nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341764(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataIC50: 68nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341771(4-{5-[(2-Phenyl-5-trifluoromethyloxazole-4-carbony...)
Affinity DataIC50: 71nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341781(4-(4-{4-[(2-Phenyl-5-trifluoromethyloxazole-4-carb...)
Affinity DataIC50: 77nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341783(4-(4-{4-[(2-Phenyl-5-trifluoromethyloxazole-4-carb...)
Affinity DataIC50: 82nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341772(5-[(2-Phenyl-5-trifluoromethyloxazole-4-carbonyl)a...)
Affinity DataIC50: 84nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341777(4-{4-[(2-Phenyl-5-trifluoromethyloxazole-4-carbony...)
Affinity DataIC50: 84nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM27947(2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)
Affinity DataIC50: 113nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341780(4-{5-[(2-Phenyl-5-trifluoromethyloxazole-4-carbony...)
Affinity DataIC50: 128nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341773(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataIC50: 128nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341775(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataIC50: 136nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341774(4-{4-[(2-Phenyl-5-trifluoromethyloxazole-4-carbony...)
Affinity DataIC50: 165nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
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