Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 8130
TargetMatrix metalloproteinase-9(Human)
Huazhong University of Science and Technology

LigandPNGBDBM234334(GM6001)
Affinity DataIC50: 0.260nMpH: 7.5 T: 2°CAssay Description:The MMP-9 assay was performed in 50 mM Tris-HCl buffer (pH 7.5, 10mM CaCl2, 150mM NaCl, 0.05% Brij-35). Then, 30ng Active MMP-9 was added to 50 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Huazhong University of Science and Technology

LigandPNGBDBM234335(Inhibitor A)
Affinity DataIC50: 175nMpH: 9.0 T: 2°CAssay Description:The TACE assay was carried out in 25 mM Tris-HCl buffer (pH 9, 2.5 μM ZnCl2 and 0.005% Brij-35). Then, 15ng TACE was added to buffer solution co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Huazhong University of Science and Technology

LigandPNGBDBM234334(GM6001)
Affinity DataIC50: 317nMpH: 9.0 T: 2°CAssay Description:The TACE assay was carried out in 25 mM Tris-HCl buffer (pH 9, 2.5 μM ZnCl2 and 0.005% Brij-35). Then, 15ng TACE was added to buffer solution co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Huazhong University of Science and Technology

LigandPNGBDBM234335(Inhibitor A)
Affinity DataIC50: 537nMpH: 7.5 T: 2°CAssay Description:The MMP-9 assay was performed in 50 mM Tris-HCl buffer (pH 7.5, 10mM CaCl2, 150mM NaCl, 0.05% Brij-35). Then, 30ng Active MMP-9 was added to 50 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed