Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 50033226
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341643(3-morpholino-N-(3-nitrobenzy l)-7-(trifluoromethyl...)
Affinity DataIC50: 0.720nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341648(Ethyl 2-(4-(5-(3-nitrobenzylamino)-7-(trifluoromet...)
Affinity DataIC50: 0.770nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341647(3-(4-(Methylsulfonyl)piperazin-1-yl)-N-(3-nitroben...)
Affinity DataIC50: 0.820nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341646(3-(4-(Cyclopropylsulfonyl)piperazin-1-yl)-N-(3-nit...)
Affinity DataIC50: 0.840nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341627(3-(4-Methylpiperazin-1-yl)-5-(3-nitrobenzylamino)-...)
Affinity DataIC50: 0.930nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341628(3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-...)
Affinity DataIC50: 0.950nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341629(3-(4-Ethylpiperazin-1-yl)-5-(3-nitrobenzylamino)-7...)
Affinity DataIC50: 1nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341631(N-(3-Nitrobenzyl)-3-(piperazin-1-yl)-7-(trifluorom...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341645(3-(4-Methylpiperazin-1-yl)-5-(3-nitrobenzyloxy)-7-...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341642(3-(piperidin-1-yl)-N-(3-nitrobenzyl)-7-(trifluorom...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341617(2-(4-(5-(3-Nitrobenzylamino)-7-(trifluoromethyl)qu...)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341632(3-(4-ethylpiperazin-1-yl)-N-(3-cyanobenzyl)-7-(tri...)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341630(tert-Butyl4-(5-(3-Nitrobenzylamino)-7-(trifluorome...)
Affinity DataIC50: 11nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341636((3Z)-N-(3-CHLOROPHENYL)-3-({3,5-DIMETHYL-4-[(4-MET...)
Affinity DataIC50: 14nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341649(Methyl 4-(5-(3-nitrobenzylamino)-7-(trifluoromethy...)
Affinity DataIC50: 43nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341644(N-(3-(4-Methylpiperazin-1-yl)-7-(trifluoromethyl)q...)
Affinity DataIC50: 99nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341618(3-(4-Acetylpiperazin-1-yl)-N-(3-nitrobenzyl)quinol...)
Affinity DataIC50: 110nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341637(5-(3-Nitrobenzyloxy)-3-(4-methylpiperazin-1-yl)qui...)
Affinity DataIC50: 140nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341641(3-(4-methylpiperazin-1-yl)-N-(pyridin-3-ylmethyl)-...)
Affinity DataIC50: 160nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341640(3-(4-Methylpiperazin-1-yl)-N-(3-nitrobenzyl)quinol...)
Affinity DataIC50: 166nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341633(3-(4-ethylpiperazin-1-yl)-N-(3-hydroxybenzyl)-7-(t...)
Affinity DataIC50: 230nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341635(3-(4-methylpiperazin-1-yl)-N-(3-fluorobenzyl)-7-(t...)
Affinity DataIC50: 450nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341639(3-(4-Methylpiperazin-1-yl)quinolin-5-yl 3-Nitroben...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341626(3-(4-Methylpiperazin-1-yl)-5-(3-nitrophenyl)quinol...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341621(N-(3-(4-acetylpiperazin-1-yl)quinolin-5-yl)-3-nitr...)
Affinity DataIC50: 2.56E+3nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341619(N-(3-(4-Methylpiperazin-1-yl)quinolin-5-yl)-3-nitr...)
Affinity DataIC50: 3.44E+3nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341620(1-(4-fluorophenyl)-N-(3-(4-methylpiperazin-1-yl)qu...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341623(3-(4-Methylpiperazin-1-yl)-5-(naphthalen-2-yl)quin...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341628(3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EPH-A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341628(3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341628(3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EPH-B2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341628(3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341628(3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341628(3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of RONMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341628(3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341628(3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341628(3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341628(3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of RETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341628(3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDGFRalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341628(3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-KitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341628(3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341628(3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Flt-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341634(3-(4-ethylpiperazin-1-yl)-N-(4-fluorobenzyl)-7-(tr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341638(5-(3-Cyanobenzyloxy)-3-(4-methylpiperazin-1-yl)qui...)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341624(5-(Furan-2-yl)-3-(4-methylpiperazin-1-yl)quinoline...)
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341625(3-(4-Methylpiperazin-1-yl)-5-(thiophen-2-yl)quinol...)
Affinity DataIC50: 1.43E+4nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341622(1-(3-(4-acetylpiperazin-1-yl)quinolin-5-yl)-3-(3-n...)
Affinity DataIC50: 2.24E+4nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed