Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50033124
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50339937(1,1',1''-(5,5',5''-(benzene-1,3,5-triyl)tris(penta...)
Affinity DataIC50: 0.560nMAssay Description:Antagonist activity at alpha9/alpha10 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiolog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50339933(1,1',1'',1'''-(5,5',5'',5'''-(benzene-1,2,4,5-tetr...)
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at alpha9/alpha10 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiolog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50339936(2,2',2''-(5,5',5''-(benzene-1,3,5-triyl)tris(penta...)
Affinity DataIC50: 3.70nMAssay Description:Antagonist activity at alpha9/alpha10 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiolog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50339934(1,1'-(3,3'-(biphenyl-4,4'-diyl)bis(propane-3,1-diy...)
Affinity DataIC50: 4.20nMAssay Description:Antagonist activity at alpha9/alpha10 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiolog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50339935(1,1',1''-(5,5',5''-(benzene-1,3,5-triyl)tris(penta...)
Affinity DataIC50: 4.80nMAssay Description:Antagonist activity at alpha9/alpha10 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiolog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50339938(1,1',1'',1'''-(5,5',5'',5'''-(benzene-1,2,4,5-tetr...)
Affinity DataIC50: 5.40nMAssay Description:Antagonist activity at alpha9/alpha10 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiolog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50339937(1,1',1''-(5,5',5''-(benzene-1,3,5-triyl)tris(penta...)
Affinity DataIC50: 8.80nMAssay Description:Antagonist activity at alpha7 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50339931(1,1'-(3,3'-(biphenyl-4,4'-diyl)bis(prop-2-yne-3,1-...)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at alpha9/alpha10 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiolog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50339936(2,2',2''-(5,5',5''-(benzene-1,3,5-triyl)tris(penta...)
Affinity DataIC50: 91nMAssay Description:Antagonist activity at alpha7 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50339938(1,1',1'',1'''-(5,5',5'',5'''-(benzene-1,2,4,5-tetr...)
Affinity DataIC50: 99nMAssay Description:Antagonist activity at alpha7 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50339935(1,1',1''-(5,5',5''-(benzene-1,3,5-triyl)tris(penta...)
Affinity DataIC50: 170nMAssay Description:Antagonist activity at alpha7 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50339933(1,1',1'',1'''-(5,5',5'',5'''-(benzene-1,2,4,5-tetr...)
Affinity DataIC50: 185nMAssay Description:Antagonist activity at alpha7 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50339932(1,1',1''-(5,5',5''-(benzene-1,3,5-triyl)tris(pent-...)
Affinity DataIC50: 670nMAssay Description:Antagonist activity at alpha9/alpha10 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiolog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50339933(1,1',1'',1'''-(5,5',5'',5'''-(benzene-1,2,4,5-tetr...)
Affinity DataIC50: 800nMAssay Description:Inhibition of alpha3beta4 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50339931(1,1'-(3,3'-(biphenyl-4,4'-diyl)bis(prop-2-yne-3,1-...)
Affinity DataIC50: 1.19E+3nMAssay Description:Antagonist activity at alpha7 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50339934(1,1'-(3,3'-(biphenyl-4,4'-diyl)bis(propane-3,1-diy...)
Affinity DataIC50: 1.51E+3nMAssay Description:Antagonist activity at alpha7 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50339933(1,1',1'',1'''-(5,5',5'',5'''-(benzene-1,2,4,5-tetr...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of alpha4beta2 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50339932(1,1',1''-(5,5',5''-(benzene-1,3,5-triyl)tris(pent-...)
Affinity DataIC50: 6.01E+3nMAssay Description:Antagonist activity at alpha7 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed