Compile Data Set for Download or QSAR
Report error Found 87 Enz. Inhib. hit(s) with all data for entry = 50033120
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339886((S)-3-(1-(2-amino-6-(4-fluorophenyl)pyrimidin-4-yl...)
Affinity DataEC50:  20nMAssay Description:Inhibition of FAAH in human T84 cell assessed as conversion of [3H]AEA to [3H]ethanolamine by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339872((S)-3-(1-(4-(5-chlorothiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataEC50:  2nMAssay Description:Inhibition of FAAH in human T84 cell assessed as conversion of [3H]AEA to [3H]ethanolamine by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339871((S)-3-(1-(4-(5-chlorothiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataEC50:  3nMAssay Description:Inhibition of FAAH in human T84 cell assessed as conversion of [3H]AEA to [3H]ethanolamine by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339891((S)-1-ethyl-3-(1-(4-(thiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataEC50:  350nMAssay Description:Inhibition of FAAH in human T84 cell assessed as conversion of [3H]AEA to [3H]ethanolamine by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50339886((S)-3-(1-(2-amino-6-(4-fluorophenyl)pyrimidin-4-yl...)
Affinity DataEC50:  100nMAssay Description:Inhibition of FAAH in rat RBL cell assessed as conversion of [3H]AEA to [3H]ethanolamine by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50339873((S)-3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataEC50:  80nMAssay Description:Inhibition of FAAH in rat RBL cell assessed as conversion of [3H]AEA to [3H]ethanolamine by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50339872((S)-3-(1-(4-(5-chlorothiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataEC50:  100nMAssay Description:Inhibition of FAAH in rat RBL cell assessed as conversion of [3H]AEA to [3H]ethanolamine by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50339871((S)-3-(1-(4-(5-chlorothiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataEC50:  280nMAssay Description:Inhibition of FAAH in rat RBL cell assessed as conversion of [3H]AEA to [3H]ethanolamine by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50339891((S)-1-ethyl-3-(1-(4-(thiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataEC50:  1.80E+3nMAssay Description:Inhibition of FAAH in rat RBL cell assessed as conversion of [3H]AEA to [3H]ethanolamine by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339871((S)-3-(1-(4-(5-chlorothiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50244890(N-(2-fluorophenyl)-4-(3-phenyl-1,2,4-thiadiazol-5-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339872((S)-3-(1-(4-(5-chlorothiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339873((S)-3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339874(2-(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)p...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339875((S)-2-(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM26739(URB 597 | URB597 | CHEMBL184238 | 3-(3-carbamoylph...)
Affinity DataIC50: 3nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50244890(N-(2-fluorophenyl)-4-(3-phenyl-1,2,4-thiadiazol-5-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339875((S)-2-(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM26739(URB 597 | URB597 | CHEMBL184238 | 3-(3-carbamoylph...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50339871((S)-3-(1-(4-(5-chlorothiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataIC50: 4nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339876(6-bromo-N-(2-fluorophenyl)-4H-spiro[benzo[d][1,3]d...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339877(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)pipe...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339878((S)-3-(1-(4-(benzofuran-2-yl)pyrimidin-2-yl)piperi...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50339872((S)-3-(1-(4-(5-chlorothiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataIC50: 8nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339879((R)-3-(1-(4-(benzofuran-2-yl)pyrimidin-2-yl)piperi...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339880(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)pipe...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339881(2-(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)p...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339884((S)-1-ethyl-3-(1-(4-(4-fluorophenyl)pyrimidin-2-yl...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50244718(cid_2809273 | CHEMBL460273 | JNJ-1661010 | N-pheny...)
Affinity DataIC50: 10nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50339879((R)-3-(1-(4-(benzofuran-2-yl)pyrimidin-2-yl)piperi...)
Affinity DataIC50: 10nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339882((S)-3-(1-(2-amino-6-(benzofuran-2-yl)pyrimidin-4-y...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339883((S)-1-ethyl-3-(1-(2-(4-fluorophenyl)pyrimidin-4-yl...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339885(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)pipe...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339886((S)-3-(1-(2-amino-6-(4-fluorophenyl)pyrimidin-4-yl...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50161517(6-phenyl-1-(5-(pyridin-2-yl)oxazol-2-yl)hexan-1-on...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50339874(2-(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)p...)
Affinity DataIC50: 18nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339878((S)-3-(1-(4-(benzofuran-2-yl)pyrimidin-2-yl)piperi...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50161517(6-phenyl-1-(5-(pyridin-2-yl)oxazol-2-yl)hexan-1-on...)
Affinity DataIC50: 25nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50339873((S)-3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataIC50: 26nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339888(1-(1-(4-(benzofuran-2-yl)pyrimidin-2-yl)piperidin-...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50339884((S)-1-ethyl-3-(1-(4-(4-fluorophenyl)pyrimidin-2-yl...)
Affinity DataIC50: 30nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339887(1-(1-(4-(benzofuran-2-yl)pyrimidin-2-yl)piperidin-...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339889((S)-1-(1-(2-(benzofuran-2-yl)pyrimidin-4-yl)piperi...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339890((S)-1-(1-(2-(4-chlorophenyl)pyrimidin-4-yl)piperid...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339891((S)-1-ethyl-3-(1-(4-(thiophen-2-yl)pyrimidin-2-yl)...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50339876(6-bromo-N-(2-fluorophenyl)-4H-spiro[benzo[d][1,3]d...)
Affinity DataIC50: 36nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50339875((S)-2-(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-...)
Affinity DataIC50: 39nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339892((S)-1-ethyl-3-(1-(2-p-tolylpyrimidin-4-yl)piperidi...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50339886((S)-3-(1-(2-amino-6-(4-fluorophenyl)pyrimidin-4-yl...)
Affinity DataIC50: 43nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339894((S)-1-ethyl-3-(1-(2-(3-fluorophenyl)pyrimidin-4-yl...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
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