Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50033190
TargetPeroxisome proliferator-activated receptor gamma(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50341151(2-methyl-2-(3-(2-(4-methylbenzoyl)-1H-benzo[d]imid...)
Affinity DataEC50:  3.30E+3nMAssay Description:Partial agonist activity at human PPARgamma expressed in CHO cells co-transfected with Gal4-responsive luciferase reporter plasmid after 24 hrs by tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50341149((E)-2-methyl-2-(3-(2-(2-(4-methylbenzoyl)-1H-benzo...)
Affinity DataEC50:  2.40E+3nMAssay Description:Partial agonist activity at human PPARalpha expressed in CHO cells co-transfected with Gal4-responsive luciferase reporter plasmid after 24 hrs by tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50341148((E)-2-methyl-2-(3-(3-(2-(4-methylbenzoyl)-1H-benzo...)
Affinity DataEC50:  3.60E+3nMAssay Description:Partial agonist activity at human PPARalpha expressed in CHO cells co-transfected with Gal4-responsive luciferase reporter plasmid after 24 hrs by tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50341147((E)-2-methyl-2-(3-(3-(2-(4-methylbenzoyl)-4,5,6,7-...)
Affinity DataEC50:  3.60E+3nMAssay Description:Partial agonist activity at human PPARalpha expressed in CHO cells co-transfected with Gal4-responsive luciferase reporter plasmid after 24 hrs by tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50341146((E)-2-(3-(3-(4,5-dimethyl-2-(4-methylbenzoyl)-1H-i...)
Affinity DataEC50:  3.60E+3nMAssay Description:Partial agonist activity at human PPARalpha expressed in CHO cells co-transfected with Gal4-responsive luciferase reporter plasmid after 24 hrs by tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50341145((E)-2-methyl-2-(3-(3-(2-(4-methylbenzoyl)-1H-imida...)
Affinity DataEC50:  620nMAssay Description:Partial agonist activity at human PPARalpha expressed in CHO cells co-transfected with Gal4-responsive luciferase reporter plasmid after 24 hrs by tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50341144((E)-2-(3-(3-(2-(4-methylbenzoyl)-1H-benzo[d]imidaz...)
Affinity DataEC50: >1.00E+4nMAssay Description:Partial agonist activity at human PPARalpha expressed in CHO cells co-transfected with Gal4-responsive luciferase reporter plasmid after 24 hrs by tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50341143((E)-2-(3-(3-(2-(4-methylbenzoyl)-1H-imidazol-1-yl)...)
Affinity DataEC50: >1.00E+4nMAssay Description:Partial agonist activity at human PPARalpha expressed in CHO cells co-transfected with Gal4-responsive luciferase reporter plasmid after 24 hrs by tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM28700(alpha-1081 | procetofenic acid | Fenofibrate | CHE...)
Affinity DataEC50:  1.20E+4nMAssay Description:Partial agonist activity at human PPARalpha expressed in CHO cells co-transfected with Gal4-responsive luciferase reporter plasmid after 24 hrs by tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor alpha(Mouse)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50341148((E)-2-methyl-2-(3-(3-(2-(4-methylbenzoyl)-1H-benzo...)
Affinity DataEC50:  1.70E+3nMAssay Description:Partial agonist activity at mouse PPARalpha expressed in CHO cells co-transfected with Gal4-responsive luciferase reporter plasmid after 24 hrs by tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50049240((+-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)m...)
Affinity DataEC50:  390nMAssay Description:Partial agonist activity at human PPARgamma expressed in CHO cells co-transfected with Gal4-responsive luciferase reporter plasmid after 24 hrs by tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50341150(2-methyl-2-(3-((2-(4-methylbenzoyl)-1H-benzo[d]imi...)
Affinity DataEC50:  6.00E+3nMAssay Description:Partial agonist activity at human PPARgamma expressed in CHO cells co-transfected with Gal4-responsive luciferase reporter plasmid after 24 hrs by tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50341149((E)-2-methyl-2-(3-(2-(2-(4-methylbenzoyl)-1H-benzo...)
Affinity DataEC50:  130nMAssay Description:Partial agonist activity at human PPARgamma expressed in CHO cells co-transfected with Gal4-responsive luciferase reporter plasmid after 24 hrs by tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50341148((E)-2-methyl-2-(3-(3-(2-(4-methylbenzoyl)-1H-benzo...)
Affinity DataEC50:  1.70E+3nMAssay Description:Partial agonist activity at human PPARgamma expressed in CHO cells co-transfected with Gal4-responsive luciferase reporter plasmid after 24 hrs by tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50341147((E)-2-methyl-2-(3-(3-(2-(4-methylbenzoyl)-4,5,6,7-...)
Affinity DataEC50:  3.00E+3nMAssay Description:Partial agonist activity at human PPARgamma expressed in CHO cells co-transfected with Gal4-responsive luciferase reporter plasmid after 24 hrs by tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50341146((E)-2-(3-(3-(4,5-dimethyl-2-(4-methylbenzoyl)-1H-i...)
Affinity DataEC50:  4.80E+3nMAssay Description:Partial agonist activity at human PPARgamma expressed in CHO cells co-transfected with Gal4-responsive luciferase reporter plasmid after 24 hrs by tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50341145((E)-2-methyl-2-(3-(3-(2-(4-methylbenzoyl)-1H-imida...)
Affinity DataEC50:  1.20E+4nMAssay Description:Partial agonist activity at human PPARgamma expressed in CHO cells co-transfected with Gal4-responsive luciferase reporter plasmid after 24 hrs by tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50341144((E)-2-(3-(3-(2-(4-methylbenzoyl)-1H-benzo[d]imidaz...)
Affinity DataEC50:  4.60E+3nMAssay Description:Partial agonist activity at human PPARgamma expressed in CHO cells co-transfected with Gal4-responsive luciferase reporter plasmid after 24 hrs by tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50341143((E)-2-(3-(3-(2-(4-methylbenzoyl)-1H-imidazol-1-yl)...)
Affinity DataEC50: >1.00E+4nMAssay Description:Partial agonist activity at human PPARgamma expressed in CHO cells co-transfected with Gal4-responsive luciferase reporter plasmid after 24 hrs by tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed