Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50033202
LigandPNGBDBM50341310(Isopropyl 9-anti-({5-Methyl-6-[(2-methylpyridin-3-...)
Affinity DataEC50:  228nMAssay Description:Agonist activity at rat GPR119 expressed in human HEK293 cells assessed as increase in cAMP level after 16 hrs by beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandPNGBDBM50341310(Isopropyl 9-anti-({5-Methyl-6-[(2-methylpyridin-3-...)
Affinity DataEC50:  227nMAssay Description:Agonist activity at rat GPR119 expressed in human HEK293 cells assessed as increase in cAMP level after 16 hrs by beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandPNGBDBM50341311((+/-)-isopropyl 8-(5-methyl-6-(2-methylpyridin-3-y...)
Affinity DataEC50:  1.24E+3nMAssay Description:Agonist activity at GPR119 in human HEK293 cells assessed as increase in cAMP level after 16 hrs by beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandPNGBDBM50341312((1R,5R,8R)-Isopropyl 8-(5-Methyl-6-(2-methylpyridi...)
Affinity DataEC50:  740nMAssay Description:Agonist activity at GPR119 in human HEK293 cells assessed as increase in cAMP level after 16 hrs by beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandPNGBDBM50341313((1S,5S,8S)-Isopropyl 8-(5-Methyl-6-(2-methylpyridi...)
Affinity DataEC50:  2.07E+3nMAssay Description:Agonist activity at GPR119 in human HEK293 cells assessed as increase in cAMP level after 16 hrs by beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandPNGBDBM50341309(isopropyl 4-(5-methyl-6-(2-methylpyridin-3-yloxy)p...)
Affinity DataEC50:  84nMAssay Description:Agonist activity at rat GPR119 expressed in human HEK293 cells assessed as increase in cAMP level after 16 hrs by beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandPNGBDBM50341309(isopropyl 4-(5-methyl-6-(2-methylpyridin-3-yloxy)p...)
Affinity DataEC50:  14nMAssay Description:Agonist activity at GPR119 in human HEK293 cells assessed as increase in cAMP level after 16 hrs by beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandPNGBDBM50341310(Isopropyl 9-anti-({5-Methyl-6-[(2-methylpyridin-3-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at GPR119 in human HEK293 cells assessed as increase in cAMP level after 16 hrs by beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandPNGBDBM50341310(Isopropyl 9-anti-({5-Methyl-6-[(2-methylpyridin-3-...)
Affinity DataEC50:  65nMAssay Description:Agonist activity at GPR119 in human HEK293 cells assessed as increase in cAMP level after 16 hrs by beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandPNGBDBM50341309(isopropyl 4-(5-methyl-6-(2-methylpyridin-3-yloxy)p...)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandPNGBDBM50341310(Isopropyl 9-anti-({5-Methyl-6-[(2-methylpyridin-3-...)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandPNGBDBM50341310(Isopropyl 9-anti-({5-Methyl-6-[(2-methylpyridin-3-...)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandPNGBDBM50341310(Isopropyl 9-anti-({5-Methyl-6-[(2-methylpyridin-3-...)
Affinity DataKi:  125nMAssay Description:Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandPNGBDBM50341310(Isopropyl 9-anti-({5-Methyl-6-[(2-methylpyridin-3-...)
Affinity DataKi:  125nMAssay Description:Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandPNGBDBM50341309(isopropyl 4-(5-methyl-6-(2-methylpyridin-3-yloxy)p...)
Affinity DataKi:  140nMAssay Description:Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandPNGBDBM50341312((1R,5R,8R)-Isopropyl 8-(5-Methyl-6-(2-methylpyridi...)
Affinity DataKi:  1.18E+3nMAssay Description:Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandPNGBDBM50341311((+/-)-isopropyl 8-(5-methyl-6-(2-methylpyridin-3-y...)
Affinity DataKi:  1.60E+3nMAssay Description:Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandPNGBDBM50341313((1S,5S,8S)-Isopropyl 8-(5-Methyl-6-(2-methylpyridi...)
Affinity DataKi:  2.27E+3nMAssay Description:Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed