Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50033045
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338718(2-(6-fluorochroman-3-yl)-8-methoxy-6-(1H-pyrazol-4...)
Affinity DataIC50: 1nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50026330(CHEMBL1684210)
Affinity DataIC50: 1nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50026332(CHEMBL1684209)
Affinity DataIC50: 1nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338703(N-cyclopropyl-3-(4-oxo-6-(1H-pyrazol-4-yl)-3,4-dih...)
Affinity DataIC50: 1nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50026328(CHEMBL1684207)
Affinity DataIC50: 1nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338722(8-methoxy-2-((3-methoxyphenoxy)methyl)-6-(1H-pyraz...)
Affinity DataIC50: 1nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50026327(CHEMBL1684206)
Affinity DataIC50: 1nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50026346(CHEMBL1684201)
Affinity DataIC50: 1nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50026347(CHEMBL1684197)
Affinity DataIC50: 1nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338714(8-methoxy-2-(6-methoxychroman-3-yl)-6-(1H-pyrazol-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338698(2-(6-methoxychroman-3-yl)-6-(1H-pyrazol-4-yl)quina...)
Affinity DataIC50: 2nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338695(2-(chroman-2-yl)-6-(1H-pyrazol-4-yl)quinazolin-4(3...)
Affinity DataIC50: 2nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338721(2-(2,3-dihydrobenzo[b][1,4]dioxin-2-yl)-8-methoxy-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338713(3-(4-(2-(dimethylamino)ethylthio)-6-(1H-pyrazol-4-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338712(3-(4-(2-(dimethylamino)ethylthio)-6-(1H-pyrazol-4-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338701(2-(6-fluorochroman-3-yl)-6-(1H-pyrazol-4-yl)quinaz...)
Affinity DataIC50: 3nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338719(8-methoxy-2-(6-methylchroman-3-yl)-6-(1H-pyrazol-4...)
Affinity DataIC50: 5nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338700(2-(6-methylchroman-3-yl)-6-(1H-pyrazol-4-yl)quinaz...)
Affinity DataIC50: 6nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338707(2-(2-(6-methoxychroman-3-yl)-6-(1H-pyrazol-4-yl)qu...)
Affinity DataIC50: 6nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338711(N-cyclopropyl-3-(4-(2-(dimethylamino)ethylthio)-6-...)
Affinity DataIC50: 6nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338720(8-methoxy-2-(7-methoxy-1,2,3,4-tetrahydronaphthale...)
Affinity DataIC50: 11nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338717(8-(2-(dimethylamino)ethoxy)-2-(6-methoxychroman-3-...)
Affinity DataIC50: 16nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338702(2-(6-(cyclopropanecarbonyl)chroman-3-yl)-6-(1H-pyr...)
Affinity DataIC50: 18nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338716(8-((2-(dimethylamino)ethyl)(methyl)amino)-2-(6-met...)
Affinity DataIC50: 21nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338708(2-((2-(6-methoxychroman-3-yl)-6-(1H-pyrazol-4-yl)q...)
Affinity DataIC50: 22nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338696(2-(5-methoxychroman-3-yl)-6-(1H-pyrazol-4-yl)quina...)
Affinity DataIC50: 31nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338705(2-((3-methoxyphenoxy)methyl)-6-(1H-pyrazol-4-yl)qu...)
Affinity DataIC50: 33nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338699((S)-2-(6-methoxychroman-3-yl)-6-(1H-pyrazol-4-yl)q...)
Affinity DataIC50: 87nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338715(8-fluoro-2-(6-methoxychroman-3-yl)-6-(1H-pyrazol-4...)
Affinity DataIC50: 104nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338706(2-cyclopropyl-6-(1H-pyrazol-4-yl)quinazolin-4(3H)-...)
Affinity DataIC50: 123nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338704(2-((2-methoxyphenoxy)methyl)-6-(1H-pyrazol-4-yl)qu...)
Affinity DataIC50: 188nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338709(N1-(2-(6-methoxychroman-3-yl)-6-(1H-pyrazol-4-yl)q...)
Affinity DataIC50: 358nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338697(2-(8-methoxychroman-3-yl)-6-(1H-pyrazol-4-yl)quina...)
Affinity DataIC50: 423nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338710(2-(6-methoxychroman-3-yl)-6-(1H-pyrazol-4-yl)-N-(p...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338694(2-(2H-chromen-3-yl)-6-(1H-pyrazol-4-yl)quinazolin-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed