Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50033169
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329261BDBM50329261((R)-2-(4-fluoro-3,5-dimethylphenylamino)-6-(4-fluo...)
Affinity DataKi:  0.0500nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340754BDBM50340754((S)-2-(4-fluoro-3,5-dimethylbenzyl)-6-(4-fluoroben...)
Affinity DataKi:  0.130nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329265BDBM50329265((R)-2-(4-fluoro-3,5-dimethylphenylamino)-6-(4-fluo...)
Affinity DataKi:  0.240nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340755BDBM50340755((S)-2-(4-fluoro-3-methylbenzyl)-6-(4-fluorobenzyla...)
Affinity DataKi:  0.25nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340756BDBM50340756((S)-6-(4-chlorobenzylamino)-2-(4-fluoro-3-methylbe...)
Affinity DataKi:  0.360nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340757BDBM50340757((S)-2-(4-fluoro-3,5-dimethylbenzyl)-6-(4-fluoro-3-...)
Affinity DataKi:  0.390nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340758BDBM50340758((S)-6-(4-fluorobenzylamino)-2-((R)-2-(4-fluorophen...)
Affinity DataKi:  0.580nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340759BDBM50340759((R)-6-(4-fluoro-3-methylbenzylamino)-2-(4-fluoro-3...)
Affinity DataKi:  0.620nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340760BDBM50340760((R)-6-(4-chlorobenzylamino)-2-(4-fluoro-3-methylph...)
Affinity DataKi:  0.680nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340761BDBM50340761((S)-6-(4-chlorobenzylamino)-2-(4-fluoro-3,5-dimeth...)
Affinity DataKi:  0.710nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340762BDBM50340762((R)-6-(4-chlorobenzylamino)-2-(4-fluoro-3-methylph...)
Affinity DataKi:  0.75nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340763BDBM50340763((R)-2-(4-fluoro-3-methylphenylamino)-6-(4-fluorobe...)
Affinity DataKi:  0.810nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340764BDBM50340764((S)-2-((R)-2-(4-fluoro-3-methylphenyl)-2-methoxyet...)
Affinity DataKi:  0.930nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329266BDBM50329266((R)-6-(4-chlorobenzylamino)-2-(4-fluoro-3,5-dimeth...)
Affinity DataKi:  1nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340765BDBM50340765((S)-6-(4-fluorophenethylamino)-2-((R)-2-(4-fluorop...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340766BDBM50340766((R)-2-(4-fluoro-3-methylphenoxy)-6-(4-fluorobenzyl...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340767BDBM50340767((S)-6-(4-chlorobenzylamino)-2-((R)-2-(4-fluorophen...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340768BDBM50340768((R)-2-(4-fluoro-3,5-dimethylphenoxy)-6-(4-fluorobe...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340769BDBM50340769((S)-2-(4-fluoro-3-methylbenzyl)-6-(4-fluoro-3-meth...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340770BDBM50340770((S)-6-(4-fluoro-3-methylbenzylamino)-2-((R)-2-(4-f...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340771BDBM50340771((S)-6-(4-chlorobenzylamino)-2-((R)-2-(4-fluoro-3-m...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340772BDBM50340772((S)-6-(4-fluoro-3-methylbenzylamino)-2-((R)-2-(4-f...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340785BDBM50340785((R)-6-(4-chlorobenzylamino)-2-(4-fluoro-3,5-dimeth...)
Affinity DataKi:  2nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329272BDBM50329272((R)-2-(4-fluoro-3,5-dimethylphenylamino)-6-(4-fluo...)
Affinity DataKi:  2.10nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329273BDBM50329273((R)-2-(4-fluoro-3,5-dimethylphenylamino)-6-(3-(4-f...)
Affinity DataKi:  2.20nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340773BDBM50340773((R)-2-(4-fluoro-3,5-dimethylphenoxy)-6-(4-fluoro-3...)
Affinity DataKi:  2.40nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340774BDBM50340774((R)-6-(4-fluoro-3-methylbenzylamino)-2-(4-fluoro-3...)
Affinity DataKi:  3nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340782BDBM50340782((R)-2-(4-fluoro-3,5-dimethylphenoxy)-7-(4-fluorobe...)
Affinity DataKi:  3.10nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340781BDBM50340781((R)-2-(4-fluoro-3,5-dimethylphenoxy)-7-(4-fluoroph...)
Affinity DataKi:  3.30nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340786BDBM50340786((R)-2-(3-chloro-4-fluorophenylamino)-6-(4-fluorobe...)
Affinity DataKi:  3.80nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340775BDBM50340775((R)-2-(4-fluoro-3,5-dimethylphenoxy)-6-(4-fluoroph...)
Affinity DataKi:  4.60nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340784BDBM50340784((S)-7-(4-fluorobenzylamino)-2-((R)-2-(4-fluorophen...)
Affinity DataKi:  4.60nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340783BDBM50340783((S)-7-(4-fluorophenethylamino)-2-((R)-2-(4-fluorop...)
Affinity DataKi:  5nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340776BDBM50340776((S)-2-(4-fluoro-3,5-dimethylbenzyl)-6-(4-fluorophe...)
Affinity DataKi:  9.5nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50329285BDBM50329285((2S,4R)-2-(2-((3-(4-fluoro-3-methylphenyl)propyl)(...)
Affinity DataKi:  11nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340777BDBM50340777((S)-2-(4-fluoro-3,5-dimethylbenzyl)-6-(4-fluoro-3-...)
Affinity DataKi:  25nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340778BDBM50340778((R)-2-(4-fluoro-3,5-dimethylphenylamino)-6-(4-fluo...)
Affinity DataKi:  30.4nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340779BDBM50340779((R)-2-(4-fluoro-3,5-dimethylphenylamino)-8-(4-fluo...)
Affinity DataKi:  273nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Panthera Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340780BDBM50340780((S)-2-(4-fluoro-3,5-dimethylbenzyl)-8-(4-fluoro-3-...)
Affinity DataKi:  577nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as proteolysis using MCA-KKVYPYPME-Dap(Dnp)-NH2 peptide substrate after 4 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed