Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50033163
TargetThymidylate synthase(Mouse)
University of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340678(1-(beta-D-2-deoxy-erythro-pentofuranosyl)-5-fluoro...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 24 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
University of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340678(1-(beta-D-2-deoxy-erythro-pentofuranosyl)-5-fluoro...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 4 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
University of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340678(1-(beta-D-2-deoxy-erythro-pentofuranosyl)-5-fluoro...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
University of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340678(1-(beta-D-2-deoxy-erythro-pentofuranosyl)-5-fluoro...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
University of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340678(1-(beta-D-2-deoxy-erythro-pentofuranosyl)-5-fluoro...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
University of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340678(1-(beta-D-2-deoxy-erythro-pentofuranosyl)-5-fluoro...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
University of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340677((5-fluorouracil)5-Fluoro-1H-pyrimidine-2,4-dione |...)
Affinity DataIC50: 20nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 24 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
University of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340677((5-fluorouracil)5-Fluoro-1H-pyrimidine-2,4-dione |...)
Affinity DataIC50: 60nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
University of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340675((S)-5-fluoro-4-hydroxy-1-(3-oxo-3,6-dihydro-2H-pyr...)
Affinity DataIC50: 63nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 24 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
University of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340675((S)-5-fluoro-4-hydroxy-1-(3-oxo-3,6-dihydro-2H-pyr...)
Affinity DataIC50: 71nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
University of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340677((5-fluorouracil)5-Fluoro-1H-pyrimidine-2,4-dione |...)
Affinity DataIC50: 220nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 4 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
University of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340676(exo-(S)-5-fluoro-4-hydroxy-1-(3-methylene-3,6-dihy...)
Affinity DataIC50: 430nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 24 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
University of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340679(exo-1-((2S,4S,5R)-4,5-dihydroxy-3-methylenetetrahy...)
Affinity DataIC50: 570nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 24 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
University of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340677((5-fluorouracil)5-Fluoro-1H-pyrimidine-2,4-dione |...)
Affinity DataIC50: 600nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
University of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340675((S)-5-fluoro-4-hydroxy-1-(3-oxo-3,6-dihydro-2H-pyr...)
Affinity DataIC50: 830nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 4 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
University of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340675((S)-5-fluoro-4-hydroxy-1-(3-oxo-3,6-dihydro-2H-pyr...)
Affinity DataIC50: 950nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
University of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340676(exo-(S)-5-fluoro-4-hydroxy-1-(3-methylene-3,6-dihy...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
University of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340679(exo-1-((2S,4S,5R)-4,5-dihydroxy-3-methylenetetrahy...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 4 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
University of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340679(exo-1-((2S,4S,5R)-4,5-dihydroxy-3-methylenetetrahy...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
University of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340679(exo-1-((2S,4S,5R)-4,5-dihydroxy-3-methylenetetrahy...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
University of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340677((5-fluorouracil)5-Fluoro-1H-pyrimidine-2,4-dione |...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
University of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340675((S)-5-fluoro-4-hydroxy-1-(3-oxo-3,6-dihydro-2H-pyr...)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
University of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340679(exo-1-((2S,4S,5R)-4,5-dihydroxy-3-methylenetetrahy...)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
University of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340676(exo-(S)-5-fluoro-4-hydroxy-1-(3-methylene-3,6-dihy...)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 4 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
University of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340676(exo-(S)-5-fluoro-4-hydroxy-1-(3-methylene-3,6-dihy...)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
University of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340675((S)-5-fluoro-4-hydroxy-1-(3-oxo-3,6-dihydro-2H-pyr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
University of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340676(exo-(S)-5-fluoro-4-hydroxy-1-(3-methylene-3,6-dihy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
University of Thessaly

Curated by ChEMBL
LigandPNGBDBM50340676(exo-(S)-5-fluoro-4-hydroxy-1-(3-methylene-3,6-dihy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed