Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50033025
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50338329(N-(2-{3-[(5-Chlorothiophen-2-yl)carbonylamino]meth...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of factor 10a by S2222 chromogenic substrate assay by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50338345(N-{2-[4-(3-Oxomorpholin-4-yl)benzoylamino]benzyl}-...)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of factor 10a by S2222 chromogenic substrate assay by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50338346(N-{2-[4-(3-Oxomorpholin-4-yl)phenylcarbamoyl]benzy...)
Affinity DataIC50: 9nMAssay Description:Inhibition of factor 10a by S2222 chromogenic substrate assay by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50338336(N-[2-({[(5-Chlorothiophen-2-yl)carbonyl]amino}meth...)
Affinity DataIC50: 11nMAssay Description:Inhibition of factor 10a by S2222 chromogenic substrate assay by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50338335(N-[3-({[(5-Chlorothiophen-2-yl)carbonyl]amino}meth...)
Affinity DataIC50: 12nMAssay Description:Inhibition of factor 10a by S2222 chromogenic substrate assay by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50338334(N-[4-({[(5-Chlorothiophen-2-yl)carbonyl]amino}meth...)
Affinity DataIC50: 13nMAssay Description:Inhibition of factor 10a by S2222 chromogenic substrate assay by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50338333(N-[3-({[(5-Chlorothiophen-2-yl)carbonyl]amino}meth...)
Affinity DataIC50: 18nMAssay Description:Inhibition of factor 10a by S2222 chromogenic substrate assay by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50338332(N-[(1R*,2R*)-2-({[(5-Chlorothiophen-2-yl)carbonyl]...)
Affinity DataIC50: 27nMAssay Description:Inhibition of factor 10a by S2222 chromogenic substrate assay by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50338341(N-[2-({[(4-Chloro-1H-pyrrol-2-yl)carbonyl]amino}me...)
Affinity DataIC50: 48nMAssay Description:Inhibition of factor 10a by S2222 chromogenic substrate assay by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50338344(N-[2-(5-Methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4...)
Affinity DataIC50: 59nMAssay Description:Inhibition of factor 10a by S2222 chromogenic substrate assay by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50338326(N-{3-[(5-Chlorothiophen-2-yl)carbonylamino]propyl}...)
Affinity DataIC50: 93nMAssay Description:Inhibition of factor 10a by S2222 chromogenic substrate assay by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50338347(N-(2-{[(5-Chlorothiophen-2-yl)carbonylamino]methyl...)
Affinity DataIC50: 204nMAssay Description:Inhibition of factor 10a by S2222 chromogenic substrate assay by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50338331(N-[(1R*,2S*)-2-({[(5-Chlorothiophen-2-yl)carbonyl]...)
Affinity DataIC50: 439nMAssay Description:Inhibition of factor 10a by S2222 chromogenic substrate assay by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50338343(N-(2-{2-[(5-Chloropyridin-2-yl)amino]-2-oxoethyl}p...)
Affinity DataIC50: 623nMAssay Description:Inhibition of factor 10a by S2222 chromogenic substrate assay by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50338338(N-(2-{[(4-Chlorobenzoyl)amino]methyl}phenyl)-5-met...)
Affinity DataIC50: 642nMAssay Description:Inhibition of factor 10a by S2222 chromogenic substrate assay by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50338327(N-{1-[(5-Methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,...)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of factor 10a by S2222 chromogenic substrate assay by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50338340(N-(2-{[(3-Chlorobenzoyl)amino]methyl}phenyl)-5-met...)
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of factor 10a by S2222 chromogenic substrate assay by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50338348(N-[2-(1-Isopropylpioeridin-4-ylcarbamoyl)benzyl]-5...)
Affinity DataIC50: 1.93E+3nMAssay Description:Inhibition of factor 10a by S2222 chromogenic substrate assay by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50338337(N-[2-({[(5-Chloropyridin-2-yl)carbonyl]amino}methy...)
Affinity DataIC50: 2.48E+3nMAssay Description:Inhibition of factor 10a by S2222 chromogenic substrate assay by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50338339(N-(2-{[(4-Chloropyridine-2-yl)carbonylamino]methyl...)
Affinity DataIC50: 4.15E+3nMAssay Description:Inhibition of factor 10a by S2222 chromogenic substrate assay by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50338330(N-(2-{[(5-Chlorothiophen-2-yl)carbonyl]amino}benzy...)
Affinity DataIC50: 5.68E+3nMAssay Description:Inhibition of factor 10a by S2222 chromogenic substrate assay by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50338328(N-({1-[(5-Methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5...)
Affinity DataIC50: 6.83E+3nMAssay Description:Inhibition of factor 10a by S2222 chromogenic substrate assay by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50338342(N-[2-({[(5-Chloro-1H-pyrrol-2-yl)carbonyl]amino}me...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of factor 10a by S2222 chromogenic substrate assay by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed