Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50033013
TargetC-C chemokine receptor type 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338145((1S,4S)-tert-butyl 5-((1S,3R)-1-isopropyl-3-((3S,4...)
Affinity DataIC50: 2.90nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 1 hrs by human whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337619(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxytetrahydr...)
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]MCP1 from human CCR2 by human whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338141((1S,4S)-cyclopentyl 5-((1S,3R)-3-(3-fluorotetrahyd...)
Affinity DataIC50: 3.10nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338135((1S,4S)-1,1,1-trifluoropropan-2-yl 5-((1S,3R)-3-(3...)
Affinity DataIC50: 3.20nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338129((1S,4S)-1,1,1-trifluoropropan-2-yl 5-((1S,3R)-1-is...)
Affinity DataIC50: 3.5nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338125((1S,4S)-tert-butyl 5-((1S,3R)-3-(3-fluorotetrahydr...)
Affinity DataIC50: 4.20nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 1 hrs by human whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338142((1S,4S)-isobutyl 5-((1S,3R)-3-(3-fluorotetrahydro-...)
Affinity DataIC50: 4.30nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338146((1S,4S)-tert-butyl 5-((1S,3R)-1-isopropyl-3-(tetra...)
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 1 hrs by human whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338124(((1S,4S)-5-benzoyl-2,5-diazabicyclo[2.2.1]heptan-2...)
Affinity DataIC50: 6.5nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 1 hrs by human whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338123(((1S,4S)-5-(cyclopentanecarbonyl)-2,5-diazabicyclo...)
Affinity DataIC50: 8.5nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 1 hrs by human whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338123(((1S,4S)-5-(cyclopentanecarbonyl)-2,5-diazabicyclo...)
Affinity DataIC50: 11.1nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338128(((1S,4S)-5-(cyclohexanecarbonyl)-2,5-diazabicyclo[...)
Affinity DataIC50: 11.6nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338122(((1S,4S)-5-(cyclobutanecarbonyl)-2,5-diazabicyclo[...)
Affinity DataIC50: 11.7nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 1 hrs by human whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338124(((1S,4S)-5-benzoyl-2,5-diazabicyclo[2.2.1]heptan-2...)
Affinity DataIC50: 12nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338120(((1S,4S)-5-(cyclopentanecarbonyl)-2,5-diazabicyclo...)
Affinity DataIC50: 12.2nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 1 hrs by human whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338136(4,4,4-trifluoro-1-((1S,4S)-5-((1S,3R)-3-(3-fluorot...)
Affinity DataIC50: 12.8nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338130(4,4,4-trifluoro-1-((1S,4S)-5-((1S,3R)-1-isopropyl-...)
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338134(((1S,4S)-5-(cyclopentanecarbonyl)-2,5-diazabicyclo...)
Affinity DataIC50: 13.9nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338131(4,4,4-trifluoro-1-((1S,4S)-5-((1S,3R)-1-isopropyl-...)
Affinity DataIC50: 14.6nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338138(2-cyclopentyl-1-((1S,4S)-5-((1S,3R)-3-(3-fluorotet...)
Affinity DataIC50: 14.7nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338143(((1S,4S)-5-(cyclohexanecarbonyl)-2,5-diazabicyclo[...)
Affinity DataIC50: 15.2nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338121(1-((1S,4S)-5-((1S,3R)-1-isopropyl-3-((3S,4S)-3-met...)
Affinity DataIC50: 17nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 1 hrs by human whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338137(4,4,4-trifluoro-1-((1S,4S)-5-((1S,3R)-3-(3-fluorot...)
Affinity DataIC50: 17.3nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338139(((1S,4S)-5-benzoyl-2,5-diazabicyclo[2.2.1]heptan-2...)
Affinity DataIC50: 17.5nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338121(1-((1S,4S)-5-((1S,3R)-1-isopropyl-3-((3S,4S)-3-met...)
Affinity DataIC50: 24.2nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338140((1S,4S)-N-tert-butyl-5-((1S,3R)-3-(3-fluorotetrahy...)
Affinity DataIC50: 28nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338119(((1S,4S)-5-(cyclobutanecarbonyl)-2,5-diazabicyclo[...)
Affinity DataIC50: 32nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 1 hrs by human whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338147(1-((1S,4S)-5-((1S,3R)-1-isopropyl-3-(tetrahydro-2H...)
Affinity DataIC50: 36.9nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 1 hrs by human whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338133(((1S,4S)-5-(cyclobutanecarbonyl)-2,5-diazabicyclo[...)
Affinity DataIC50: 38.4nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338132(1-((1S,4S)-5-((1S,3R)-3-(3-fluorotetrahydro-2H-pyr...)
Affinity DataIC50: 39.5nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338144(((1S,4S)-5-((1S,3R)-3-(3-fluorotetrahydro-2H-pyran...)
Affinity DataIC50: 75.9nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338127(((1S,4S)-5-(cyclopropanecarbonyl)-2,5-diazabicyclo...)
Affinity DataIC50: 130nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338126(tert-butyl 4-((1S,3R)-1-isopropyl-3-((3S,4S)-3-met...)
Affinity DataIC50: 251nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated 1 hrs by human whole cell binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
LigandPNGBDBM50337619(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxytetrahydr...)
Affinity DataIC50: 1.70E+3nMAssay Description:Displacement of dofetilide from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed