Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50033508
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Cemm-Research Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50178769(6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...)
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant GST-tagged SIRT1 expressed in 293T cells by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Cemm-Research Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50216689(2-cyano-3-(5-(2,5-dichlorophenyl)furan-2-yl)-N-(qu...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of SIRT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Cemm-Research Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50346541(CHEMBL1797749)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of SIRT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Cemm-Research Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50178769(6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxa...)
Affinity DataIC50: 1.96E+4nMAssay Description:Inhibition of human recombinant GST-tagged SIRT2 by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Cemm-Research Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50156760(2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of human recombinant GST-tagged SIRT2 using acetylated HeLa histones substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Cemm-Research Center For Molecular Medicine of The Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50156760(2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...)
Affinity DataIC50: 6.80E+4nMAssay Description:Inhibition of human recombinant GST-tagged SIRT1 using acetylated HeLa histones substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed