Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50033089
TargetProteinase-activated receptor 2(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50339244(2-amino-N-((4S,7S,13S,16S)-13-sec-butyl-4-carbamoy...)
Affinity DataEC50:  142nMAssay Description:Agonist activity at PAR2 in human 16HBE14o cells assessed as increase in intracellular calcium levels measured every 15 second for 2 hrs by xCelligen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50339245(6-amino-N-((4S,7S,13S,16S)-13-sec-butyl-4-carbamoy...)
Affinity DataEC50:  311nMAssay Description:Agonist activity at PAR2 in human 16HBE14o cells assessed as increase in intracellular calcium levels measured every 15 second for 2 hrs by xCelligen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50339246(allyl(3S,6S,12S,15S,18S)-6-sec-butyl-18-carbamoyl-...)
Affinity DataEC50:  138nMAssay Description:Agonist activity at PAR2 in human 16HBE14o cells assessed as increase in intracellular calcium levels measured every 15 second for 2 hrs by xCelligen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50339244(2-amino-N-((4S,7S,13S,16S)-13-sec-butyl-4-carbamoy...)
Affinity DataEC50:  1.77E+3nMAssay Description:Agonist activity at PAR2 in human 16HBE14o cells assessed as increase in intracellular calcium levels by in vitro physiological response assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50339245(6-amino-N-((4S,7S,13S,16S)-13-sec-butyl-4-carbamoy...)
Affinity DataEC50:  2.60E+3nMAssay Description:Agonist activity at PAR2 in human 16HBE14o cells assessed as increase in intracellular calcium levels by in vitro physiological response assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50339247(6-amino-N-((4S,7S,13S,16S)-13-sec-butyl-4-carbamoy...)
Affinity DataEC50:  3.50E+3nMAssay Description:Agonist activity at PAR2 in human 16HBE14o cells assessed as increase in intracellular calcium levels by in vitro physiological response assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50339248(4-amino-N-((4S,7S,13S,16S)-13-sec-butyl-4-carbamoy...)
Affinity DataEC50:  6.59E+3nMAssay Description:Agonist activity at PAR2 in human 16HBE14o cells assessed as increase in intracellular calcium levels by in vitro physiological response assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50339246(allyl(3S,6S,12S,15S,18S)-6-sec-butyl-18-carbamoyl-...)
Affinity DataEC50:  840nMAssay Description:Agonist activity at PAR2 in human 16HBE14o cells assessed as increase in intracellular calcium levels by in vitro physiological response assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed