Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50033082
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM32628(Fumitremorgin C | FTC)
Affinity DataIC50: 800nMAssay Description:Inhibition of ABCG2 expressed in human NCI-H460 cells assessed as inhibition of PhA accumulation after 2 to 20 hrs relative to fumitremorgin CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM19460(CHEMBL376915 | YS04 | (2S)-5,7-dihydroxy-2-(4-hydr...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of ABCG2 expressed in human NCI-H460 cells assessed as inhibition of PhA accumulation after 2 to 20 hrs relative to fumitremorgin CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50339152((S)-2-(3,5-dihydroxyphenyl)-5,7-dihydroxy-6,8-bis(...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of ABCG2 expressed in human NCI-H460 cells assessed as inhibition of PhA accumulation after 2 to 20 hrs relative to fumitremorgin CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50339155(6-(3,7-dimethylocta-2,6-dienyl)-3,5,7-trihydroxy-2...)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of ABCG2 expressed in human NCI-H460 cells assessed as inhibition of PhA accumulation after 2 to 20 hrs relative to fumitremorgin CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50064888(5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,7-dimeth...)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of ABCG2 expressed in human NCI-H460 cells assessed as inhibition of PhA accumulation after 2 to 20 hrs relative to fumitremorgin CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50339159(5-Hydroxy-3-(4-hydroxy-3-methyl-but-2-enyl)-8,8-di...)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of ABCG2 expressed in human NCI-H460 cells assessed as inhibition of PhA accumulation after 2 to 20 hrs relative to fumitremorgin CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50339151((2S)-5,7,3'-trihydroxy-4'-methoxy-8-(3''-methylbut...)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of ABCG2 expressed in human NCI-H460 cells assessed as inhibition of PhA accumulation after 2 to 20 hrs relative to fumitremorgin CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50339158(5,7,3'-trihydroxy-3,5'-dimethoxy-2'-(3'-methylbut-...)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of ABCG2 expressed in human NCI-H460 cells assessed as inhibition of PhA accumulation after 2 to 20 hrs relative to fumitremorgin CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of ABCG2 expressed in human NCI-H460 cells assessed as inhibition of PhA accumulation after 2 to 20 hrs relative to fumitremorgin CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50339156((S)-8-(3,7-dimethylocta-2,6-dienyl)-5,7-dihydroxy-...)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of ABCG2 expressed in human NCI-H460 cells assessed as inhibition of PhA accumulation after 2 to 20 hrs relative to fumitremorgin CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50339153((2S)-5,7,3',5'-tetrahydroxy-8-[3'',8''-dimethyloct...)
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of ABCG2 expressed in human NCI-H460 cells assessed as inhibition of PhA accumulation after 2 to 20 hrs relative to fumitremorgin CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50339157(5,4'-dihydroxy-3,7,3'-trimethoxyflavone | 5-Hydrox...)
Affinity DataIC50: 1.72E+4nMAssay Description:Inhibition of ABCG2 expressed in human NCI-H460 cells assessed as inhibition of PhA accumulation after 2 to 20 hrs relative to fumitremorgin CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50339154((2S)-5,7-dihydroxy-4'-methoxy-8-prenylflavanone | ...)
Affinity DataIC50: 2.26E+4nMAssay Description:Inhibition of ABCG2 expressed in human NCI-H460 cells assessed as inhibition of PhA accumulation after 2 to 20 hrs relative to fumitremorgin CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed