Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50032927
TargetSodium-dependent serotonin transporter(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM25870(CITALOPRAM HYDROBROMIDE | [3H]Escitalopram | Escit...)
Affinity DataIC50: 19nMAssay Description:Inhibition of [3H]-serotonin reuptake at human SERT expressed in HEK293 cells after 15 to 20 mins by fluorescence neurotransmitter transporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50063544(1-Methyl-2-(4-methylsulfanyl-phenyl)-ethylamine | ...)
Affinity DataIC50: 200nMAssay Description:Inhibition of [3H]-serotonin reuptake at human SERT expressed in HEK293 cells after 15 to 20 mins by fluorescence neurotransmitter transporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50005247(CHEMBL6731 | MDA | (S)-(+)-2-Benzo[1,3]dioxol-5-yl...)
Affinity DataIC50: 900nMAssay Description:Inhibition of [3H]-serotonin reuptake at human SERT expressed in HEK293 cells after 15 to 20 mins by fluorescence neurotransmitter transporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50010588(DL-(3,4-Methylenedioxy)methamphetamine | N-Methyl-...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of [3H]-serotonin reuptake at human SERT expressed in HEK293 cells after 15 to 20 mins by fluorescence neurotransmitter transporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50336553(1,3-bis(3,4-methylenedioxyphenyl)-2-propamine | CH...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of [3H]-serotonin reuptake at human SERT expressed in HEK293 cells after 15 to 20 mins by fluorescence neurotransmitter transporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50336555(1,3-Bis(4-chlorophenyl)-2-propanamine | CHEMBL1672...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of [3H]-serotonin reuptake at human SERT expressed in HEK293 cells after 15 to 20 mins by fluorescence neurotransmitter transporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50336556(2-N-Ethylamino-1,3-di(4-methylthiophenyl)propane |...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of [3H]-serotonin reuptake at human SERT expressed in HEK293 cells after 15 to 20 mins by fluorescence neurotransmitter transporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50336554(1,3-bis(4-(methylthio)phenyl)propan-2-amine | 2-Am...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of [3H]-serotonin reuptake at human SERT expressed in HEK293 cells after 15 to 20 mins by fluorescence neurotransmitter transporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50336557(2-N-Formylamino-1,3-di(4-methylthiophenyl)propane ...)
Affinity DataIC50: 1.57E+4nMAssay Description:Inhibition of [3H]-serotonin reuptake at human SERT expressed in HEK293 cells after 15 to 20 mins by fluorescence neurotransmitter transporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed