Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50045926
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50088501(CHEMBL3526984)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using nifedipine substrate by HPLC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50088501(CHEMBL3526984)
Affinity DataIC50: 8.22E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam substrate by HPLC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50336575(cis-(1'-Acetyl-N-{(1R)-1-[3,5-bis(trifluoromethyl)...)
Affinity DataIC50: 9.72E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using nifedipine substrate by HPLC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50336575(cis-(1'-Acetyl-N-{(1R)-1-[3,5-bis(trifluoromethyl)...)
Affinity DataIC50: 9.86E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam substrate by HPLC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50336575(cis-(1'-Acetyl-N-{(1R)-1-[3,5-bis(trifluoromethyl)...)
Affinity DataKi:  4.93E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam substrate by HPLC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed